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Falls prevention through physical and cognitive training (falls PACT) in older adults with mild cognitive impairment: a randomized controlled trial protocol.
BMC Geriatr. 2018 08 24; 18(1):193.BG

Abstract

BACKGROUND

The presence of mild cognitive impairment (MCI) in older adults increases their fall risk. While physical exercise is effective in reducing falls rate and risk of falls, and cognitive training in improving cognitive functioning in healthy older adults, their effectiveness in preventing falls and reducing risks of falls in MCI when administered simultaneously is not yet established. Therefore, this study aims to determine the effectiveness of combined physical and cognitive training in preventing falls and decreasing risks of falls among community-dwelling older persons with MCI.

METHODS/DESIGN

This is a single-blind, multicentre, randomized controlled trial. At least ninety-three community-dwelling older adults with MCI aged 60 or above will be recruited. They will be randomly allocated into four groups: Physical Training alone (PT), Cognitive Training alone (CT), combined Physical And Cognitive Training (PACT) and Waitlist Group (WG). The PT group will perform exercises (flexibility, endurance, strengthening, and balance training) for 60-90 min three times per week for 12 weeks. The CT group will be involved in a paper-based training focusing on orientation, memory, attention and executive functioning for 60-90 min per session, once a week for 12 weeks. The PACT group will undergo cognitive training incorporated in physical exercise for 60-90 min three times per week for 12 weeks. The WG will receive the intervention, combined physical and cognitive training, at a later date. Assessors blinded to participant allocation will conduct pre-intervention, post-intervention, and 6-month follow-up assessments. The primary outcome measure will be falls rate. The secondary outcome measures will be Physiologic Profile Assessment and Falls Risk for Older Persons in the Community, and assessments that evaluate cognitive, physical and psychological factors related to falls.

DISCUSSION

Considering the possible physical, social, financial and psychological consequences of a fall, we hope to provide insights on the effectiveness of combining physical and cognitive training on falls and fall-related factors for older adults with MCI. It is projected that the combined interventions will lead to significantly lower falls rate and reduced risk of falls compared to using single or no intervention.

TRIAL REGISTRATION

ClinicalTrials.gov NCT03167840 . Registered on May 30, 2017.

Authors+Show Affiliations

Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, SAR, China. Department of Physical Therapy, College of Rehabilitation Sciences, University of Santo Tomas, Manila, Philippines.Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, SAR, China. William.Tsang@polyu.edu.hk.

Pub Type(s)

Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

30143002

Citation

Lipardo, Donald S., and William W N. Tsang. "Falls Prevention Through Physical and Cognitive Training (falls PACT) in Older Adults With Mild Cognitive Impairment: a Randomized Controlled Trial Protocol." BMC Geriatrics, vol. 18, no. 1, 2018, p. 193.
Lipardo DS, Tsang WWN. Falls prevention through physical and cognitive training (falls PACT) in older adults with mild cognitive impairment: a randomized controlled trial protocol. BMC Geriatr. 2018;18(1):193.
Lipardo, D. S., & Tsang, W. W. N. (2018). Falls prevention through physical and cognitive training (falls PACT) in older adults with mild cognitive impairment: a randomized controlled trial protocol. BMC Geriatrics, 18(1), 193. https://doi.org/10.1186/s12877-018-0868-2
Lipardo DS, Tsang WWN. Falls Prevention Through Physical and Cognitive Training (falls PACT) in Older Adults With Mild Cognitive Impairment: a Randomized Controlled Trial Protocol. BMC Geriatr. 2018 08 24;18(1):193. PubMed PMID: 30143002.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Falls prevention through physical and cognitive training (falls PACT) in older adults with mild cognitive impairment: a randomized controlled trial protocol. AU - Lipardo,Donald S, AU - Tsang,William W N, Y1 - 2018/08/24/ PY - 2017/07/04/received PY - 2018/07/31/accepted PY - 2018/8/26/entrez PY - 2018/8/26/pubmed PY - 2019/4/26/medline KW - Accidental falls KW - Cognitive training KW - Falls rate KW - Mild cognitive impairment KW - Older adults KW - Physical exercise SP - 193 EP - 193 JF - BMC geriatrics JO - BMC Geriatr VL - 18 IS - 1 N2 - BACKGROUND: The presence of mild cognitive impairment (MCI) in older adults increases their fall risk. While physical exercise is effective in reducing falls rate and risk of falls, and cognitive training in improving cognitive functioning in healthy older adults, their effectiveness in preventing falls and reducing risks of falls in MCI when administered simultaneously is not yet established. Therefore, this study aims to determine the effectiveness of combined physical and cognitive training in preventing falls and decreasing risks of falls among community-dwelling older persons with MCI. METHODS/DESIGN: This is a single-blind, multicentre, randomized controlled trial. At least ninety-three community-dwelling older adults with MCI aged 60 or above will be recruited. They will be randomly allocated into four groups: Physical Training alone (PT), Cognitive Training alone (CT), combined Physical And Cognitive Training (PACT) and Waitlist Group (WG). The PT group will perform exercises (flexibility, endurance, strengthening, and balance training) for 60-90 min three times per week for 12 weeks. The CT group will be involved in a paper-based training focusing on orientation, memory, attention and executive functioning for 60-90 min per session, once a week for 12 weeks. The PACT group will undergo cognitive training incorporated in physical exercise for 60-90 min three times per week for 12 weeks. The WG will receive the intervention, combined physical and cognitive training, at a later date. Assessors blinded to participant allocation will conduct pre-intervention, post-intervention, and 6-month follow-up assessments. The primary outcome measure will be falls rate. The secondary outcome measures will be Physiologic Profile Assessment and Falls Risk for Older Persons in the Community, and assessments that evaluate cognitive, physical and psychological factors related to falls. DISCUSSION: Considering the possible physical, social, financial and psychological consequences of a fall, we hope to provide insights on the effectiveness of combining physical and cognitive training on falls and fall-related factors for older adults with MCI. It is projected that the combined interventions will lead to significantly lower falls rate and reduced risk of falls compared to using single or no intervention. TRIAL REGISTRATION: ClinicalTrials.gov NCT03167840 . Registered on May 30, 2017. SN - 1471-2318 UR - https://www.unboundmedicine.com/medline/citation/30143002/Falls_prevention_through_physical_and_cognitive_training__falls_PACT__in_older_adults_with_mild_cognitive_impairment:_a_randomized_controlled_trial_protocol_ L2 - https://bmcgeriatr.biomedcentral.com/articles/10.1186/s12877-018-0868-2 DB - PRIME DP - Unbound Medicine ER -