Tags

Type your tag names separated by a space and hit enter

Pneumococcal disease during Hajj and Umrah: Research agenda for evidence-based vaccination policy for these events.
Travel Med Infect Dis. 2019 May - Jun; 29:8-15.TM

Abstract

Pneumococcal disease is an important cause of morbidity and mortality worldwide with a significant financial burden. Pneumococcal vaccines are available and recommended in many countries for at-risk populations including young children, the elderly and those with underlying medical conditions. The Hajj and Umrah mass gatherings attract millions of Muslim pilgrims to the Kingdom of Saudi Arabia each year. These events increase the risk of pneumococcal disease especially among the large number of elderly pilgrims with co-morbidities. However, there is no unified official policy for vaccination against pneumococcal disease for pilgrims attending Hajj and Umrah, largely due to the lack of a strong evidence-base in the context of these events. Here we review knowledge gaps regarding pneumococcal disease during Hajj and Umrah and highlight important research agendas to strengthen the evidence-base to inform pneumococcal vaccination policy for pilgrims. Available data indicates that the true clinical and financial burdens of pneumococcal disease at Hajj and Umrah are still not determined. There is limited information on antimicrobial resistance among S. pneumoniae isolated from diseased pilgrims and no information on the serotypes involved. Finally, the efficacy and effectiveness of the current vaccines in the context of Hajj and Umrah have not been studied. Research agendas proposed in this article would help fill knowledge gaps regarding pneumococcal disease at Hajj and Umrah and would constitute a strong basis for an informed and potentially unified policy regarding pneumococcal vaccination for these events.

Authors+Show Affiliations

The Global Centre for Mass Gatherings Medicine, Ministry of Health, Riyadh, Saudi Arabia. Electronic address: saber.yezli@gmail.com.German National Reference Center for Streptococci, Department of Medical Microbiology, University Hospital RWTH Aachen, Aachen, Germany.National Centre for Immunisation Research and Surveillance (NCIRS), The Children's Hospital, Westmead, University of Sydney, Sydney, Australia.The Global Centre for Mass Gatherings Medicine, Ministry of Health, Riyadh, Saudi Arabia.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

30144535

Citation

Yezli, Saber, et al. "Pneumococcal Disease During Hajj and Umrah: Research Agenda for Evidence-based Vaccination Policy for These Events." Travel Medicine and Infectious Disease, vol. 29, 2019, pp. 8-15.
Yezli S, van der Linden M, Booy R, et al. Pneumococcal disease during Hajj and Umrah: Research agenda for evidence-based vaccination policy for these events. Travel Med Infect Dis. 2019;29:8-15.
Yezli, S., van der Linden, M., Booy, R., & AlOtaibi, B. (2019). Pneumococcal disease during Hajj and Umrah: Research agenda for evidence-based vaccination policy for these events. Travel Medicine and Infectious Disease, 29, 8-15. https://doi.org/10.1016/j.tmaid.2018.08.005
Yezli S, et al. Pneumococcal Disease During Hajj and Umrah: Research Agenda for Evidence-based Vaccination Policy for These Events. Travel Med Infect Dis. 2019 May - Jun;29:8-15. PubMed PMID: 30144535.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pneumococcal disease during Hajj and Umrah: Research agenda for evidence-based vaccination policy for these events. AU - Yezli,Saber, AU - van der Linden,Mark, AU - Booy,Robert, AU - AlOtaibi,Badriah, Y1 - 2018/08/23/ PY - 2018/05/03/received PY - 2018/08/21/revised PY - 2018/08/22/accepted PY - 2018/8/26/pubmed PY - 2019/7/20/medline PY - 2018/8/26/entrez KW - Hajj KW - Mass gathering KW - Pneumonia KW - Streptococcus pneumoniae KW - Umrah KW - Vaccine SP - 8 EP - 15 JF - Travel medicine and infectious disease JO - Travel Med Infect Dis VL - 29 N2 - Pneumococcal disease is an important cause of morbidity and mortality worldwide with a significant financial burden. Pneumococcal vaccines are available and recommended in many countries for at-risk populations including young children, the elderly and those with underlying medical conditions. The Hajj and Umrah mass gatherings attract millions of Muslim pilgrims to the Kingdom of Saudi Arabia each year. These events increase the risk of pneumococcal disease especially among the large number of elderly pilgrims with co-morbidities. However, there is no unified official policy for vaccination against pneumococcal disease for pilgrims attending Hajj and Umrah, largely due to the lack of a strong evidence-base in the context of these events. Here we review knowledge gaps regarding pneumococcal disease during Hajj and Umrah and highlight important research agendas to strengthen the evidence-base to inform pneumococcal vaccination policy for pilgrims. Available data indicates that the true clinical and financial burdens of pneumococcal disease at Hajj and Umrah are still not determined. There is limited information on antimicrobial resistance among S. pneumoniae isolated from diseased pilgrims and no information on the serotypes involved. Finally, the efficacy and effectiveness of the current vaccines in the context of Hajj and Umrah have not been studied. Research agendas proposed in this article would help fill knowledge gaps regarding pneumococcal disease at Hajj and Umrah and would constitute a strong basis for an informed and potentially unified policy regarding pneumococcal vaccination for these events. SN - 1873-0442 UR - https://www.unboundmedicine.com/medline/citation/30144535/Pneumococcal_disease_during_Hajj_and_Umrah:_Research_agenda_for_evidence_based_vaccination_policy_for_these_events_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1477-8939(18)30281-3 DB - PRIME DP - Unbound Medicine ER -