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Cannabidiol attenuates delta 9-tetrahydrocannabinol-like discriminative stimulus effects of cannabinol.
Eur J Pharmacol. 1986 Jun 17; 125(2):301-4.EJ

Abstract

Interaction effects of cannabidiol (CBD) and cannabinol (CBN) were examined using a drug discrimination procedure in which rats had been trained to discriminate between 3 mg/kg of delta 9-tetrahydrocannabinol (delta 9-THC) and vehicle (2 ml/kg). The generalization effects of CBN to delta 9-THC were attenuated when CBN was administered together with CBD. The results were time- and dose-dependent.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3017729

Citation

Hiltunen, A J., and T U. Järbe. "Cannabidiol Attenuates Delta 9-tetrahydrocannabinol-like Discriminative Stimulus Effects of Cannabinol." European Journal of Pharmacology, vol. 125, no. 2, 1986, pp. 301-4.
Hiltunen AJ, Järbe TU. Cannabidiol attenuates delta 9-tetrahydrocannabinol-like discriminative stimulus effects of cannabinol. Eur J Pharmacol. 1986;125(2):301-4.
Hiltunen, A. J., & Järbe, T. U. (1986). Cannabidiol attenuates delta 9-tetrahydrocannabinol-like discriminative stimulus effects of cannabinol. European Journal of Pharmacology, 125(2), 301-4.
Hiltunen AJ, Järbe TU. Cannabidiol Attenuates Delta 9-tetrahydrocannabinol-like Discriminative Stimulus Effects of Cannabinol. Eur J Pharmacol. 1986 Jun 17;125(2):301-4. PubMed PMID: 3017729.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cannabidiol attenuates delta 9-tetrahydrocannabinol-like discriminative stimulus effects of cannabinol. AU - Hiltunen,A J, AU - Järbe,T U, PY - 1986/6/17/pubmed PY - 1986/6/17/medline PY - 1986/6/17/entrez SP - 301 EP - 4 JF - European journal of pharmacology JO - Eur J Pharmacol VL - 125 IS - 2 N2 - Interaction effects of cannabidiol (CBD) and cannabinol (CBN) were examined using a drug discrimination procedure in which rats had been trained to discriminate between 3 mg/kg of delta 9-tetrahydrocannabinol (delta 9-THC) and vehicle (2 ml/kg). The generalization effects of CBN to delta 9-THC were attenuated when CBN was administered together with CBD. The results were time- and dose-dependent. SN - 0014-2999 UR - https://www.unboundmedicine.com/medline/citation/3017729/Cannabidiol_attenuates_delta_9_tetrahydrocannabinol_like_discriminative_stimulus_effects_of_cannabinol_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0014-2999(86)90042-7 DB - PRIME DP - Unbound Medicine ER -