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Statin Intolerance.
Rev Cardiovasc Med. 2018; 19(S1):S9-S19.RC

Abstract

Statins are critical medications to prevent and treat cardiovascular disease2 and they are generally very well tolerated. In some instances, however, statin intolerance may limit use of these lifesaving medications. Statin intolerance has many definitions but is commonly diagnosed when a patient is unable to continue statin therapy due to perceived, or objectively documented, adverse effects. A very high rate of discontinuation of statin therapy warrants a closer look at the implications from the standpoint of cardiovascular risk in statin-intolerant patients, as well as an evaluation of the available options to help patients maintain their statin therapy and understand the potential benefits of such therapy.

Authors+Show Affiliations

Division of Cardiology, Advocate Heart Institute at Advocate Lutheran General Hospital, Park Ridge, IL.Departments of Medicine & Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

30207553

Citation

Brown, Alan S., and Karol E. Watson. "Statin Intolerance." Reviews in Cardiovascular Medicine, vol. 19, no. S1, 2018, pp. S9-S19.
Brown AS, Watson KE. Statin Intolerance. Rev Cardiovasc Med. 2018;19(S1):S9-S19.
Brown, A. S., & Watson, K. E. (2018). Statin Intolerance. Reviews in Cardiovascular Medicine, 19(S1), S9-S19.
Brown AS, Watson KE. Statin Intolerance. Rev Cardiovasc Med. 2018;19(S1):S9-S19. PubMed PMID: 30207553.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Statin Intolerance. AU - Brown,Alan S, AU - Watson,Karol E, PY - 2018/9/13/entrez PY - 2018/9/13/pubmed PY - 2019/7/17/medline SP - S9 EP - S19 JF - Reviews in cardiovascular medicine JO - Rev Cardiovasc Med VL - 19 IS - S1 N2 - Statins are critical medications to prevent and treat cardiovascular disease2 and they are generally very well tolerated. In some instances, however, statin intolerance may limit use of these lifesaving medications. Statin intolerance has many definitions but is commonly diagnosed when a patient is unable to continue statin therapy due to perceived, or objectively documented, adverse effects. A very high rate of discontinuation of statin therapy warrants a closer look at the implications from the standpoint of cardiovascular risk in statin-intolerant patients, as well as an evaluation of the available options to help patients maintain their statin therapy and understand the potential benefits of such therapy. SN - 1530-6550 UR - https://www.unboundmedicine.com/medline/citation/30207553/Statin_Intolerance_ L2 - https://medlineplus.gov/cholesterolmedicines.html DB - PRIME DP - Unbound Medicine ER -