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Hypermobile Ehlers-Danlos syndrome and pregnancy.
Obstet Med 2018; 11(3):104-109OM

Abstract

Ehlers-Danlos syndromes are a clinically and genetically heterogeneous group of rare inherited connective tissue disorders. Hypermobile Ehlers-Danlos syndrome is one of the common types and not infrequently encountered in pregnancy. While, in the majority of women with hypermobile Ehlers-Danlos syndrome, the pregnancy is uncomplicated, it is important to be aware of the condition in view of potential complications such as recurrent joint dislocations and history of surgical joint stabilization procedures, secondary autonomic pain and postural orthostatic tachycardia syndrome. Increased awareness of the condition and a multi-disciplinary approach to the management of these women in pregnancy result in good outcome for the mother and the baby. We report the clinical characteristics and outcome of pregnancies in eight women with hypermobile Ehlers-Danlos syndrome and present a review of the literature with particular reference to management in a pregnant woman with joint hypermobility syndrome.

Authors+Show Affiliations

Department of Obstetrics, Southend University Hospitals NHS Foundation Trust, UK.Department of Obstetrics, Southend University Hospitals NHS Foundation Trust, UK.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

30214474

Citation

Karthikeyan, Akilandeswari, and Narayanaswamy Venkat-Raman. "Hypermobile Ehlers-Danlos Syndrome and Pregnancy." Obstetric Medicine, vol. 11, no. 3, 2018, pp. 104-109.
Karthikeyan A, Venkat-Raman N. Hypermobile Ehlers-Danlos syndrome and pregnancy. Obstet Med. 2018;11(3):104-109.
Karthikeyan, A., & Venkat-Raman, N. (2018). Hypermobile Ehlers-Danlos syndrome and pregnancy. Obstetric Medicine, 11(3), pp. 104-109. doi:10.1177/1753495X18754577.
Karthikeyan A, Venkat-Raman N. Hypermobile Ehlers-Danlos Syndrome and Pregnancy. Obstet Med. 2018;11(3):104-109. PubMed PMID: 30214474.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hypermobile Ehlers-Danlos syndrome and pregnancy. AU - Karthikeyan,Akilandeswari, AU - Venkat-Raman,Narayanaswamy, Y1 - 2018/03/20/ PY - 2017/08/24/received PY - 2017/12/14/accepted PY - 2018/9/15/entrez PY - 2018/9/15/pubmed PY - 2018/9/15/medline KW - High-risk pregnancy KW - maternal-fetal medicine SP - 104 EP - 109 JF - Obstetric medicine JO - Obstet Med VL - 11 IS - 3 N2 - Ehlers-Danlos syndromes are a clinically and genetically heterogeneous group of rare inherited connective tissue disorders. Hypermobile Ehlers-Danlos syndrome is one of the common types and not infrequently encountered in pregnancy. While, in the majority of women with hypermobile Ehlers-Danlos syndrome, the pregnancy is uncomplicated, it is important to be aware of the condition in view of potential complications such as recurrent joint dislocations and history of surgical joint stabilization procedures, secondary autonomic pain and postural orthostatic tachycardia syndrome. Increased awareness of the condition and a multi-disciplinary approach to the management of these women in pregnancy result in good outcome for the mother and the baby. We report the clinical characteristics and outcome of pregnancies in eight women with hypermobile Ehlers-Danlos syndrome and present a review of the literature with particular reference to management in a pregnant woman with joint hypermobility syndrome. SN - 1753-495X UR - https://www.unboundmedicine.com/medline/citation/30214474/Hypermobile_Ehlers_Danlos_syndrome_and_pregnancy_ L2 - http://journals.sagepub.com/doi/full/10.1177/1753495X18754577?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -