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Oral supplements in atopic dermatitis.
Clin Dermatol. 2018 Sep - Oct; 36(5):653-658.CD

Abstract

Atopic dermatitis (AD) is the most common chronic inflammatory skin disorder. The disease is typified by chronic pruritus, a series of signs and symptoms associated with immune dysfunction (eg, increased immunoglobulin E mediated allergies), and abnormal skin barrier dysfunction (eg, increased response to irritants). Due to the chronic itch and reactivity, patients and parents of affected children will seek therapy. Therapies range from emollients to topical medicaments, including topical corticosteroids, and immunosuppressive agents. Due to concerns about the side effects of the available agents, patients and their loved ones will often seek "natural" agents as therapy. Oral agents that have been tried in (AD) include probiotics, vitamins, oils, and such traditional therapeutics as Chinese herbals and Ayurvedic agents. At this time probiotics may be promising, but there are inadequate data to determine their efficacy. In addition, there are significant concerns for the risks associated with Chinese herbals, which may be associated with liver failure and death, and Ayurvedic agents, which may be tainted with heavy metals. The safest and most effective natural agents are topically applied emollients.

Authors+Show Affiliations

Department of Dermatology, Mount Sinai West, New York, New York, USA.Department of Dermatology, Mount Sinai West, New York, New York, USA. Electronic address: Nanette.silverberg@mountsinai.org.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

30217278

Citation

Fenner, Justine, and Nanette B. Silverberg. "Oral Supplements in Atopic Dermatitis." Clinics in Dermatology, vol. 36, no. 5, 2018, pp. 653-658.
Fenner J, Silverberg NB. Oral supplements in atopic dermatitis. Clin Dermatol. 2018;36(5):653-658.
Fenner, J., & Silverberg, N. B. (2018). Oral supplements in atopic dermatitis. Clinics in Dermatology, 36(5), 653-658. https://doi.org/10.1016/j.clindermatol.2018.05.010
Fenner J, Silverberg NB. Oral Supplements in Atopic Dermatitis. Clin Dermatol. 2018;36(5):653-658. PubMed PMID: 30217278.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oral supplements in atopic dermatitis. AU - Fenner,Justine, AU - Silverberg,Nanette B, Y1 - 2018/06/01/ PY - 2018/9/16/entrez PY - 2018/9/16/pubmed PY - 2019/1/4/medline SP - 653 EP - 658 JF - Clinics in dermatology JO - Clin. Dermatol. VL - 36 IS - 5 N2 - Atopic dermatitis (AD) is the most common chronic inflammatory skin disorder. The disease is typified by chronic pruritus, a series of signs and symptoms associated with immune dysfunction (eg, increased immunoglobulin E mediated allergies), and abnormal skin barrier dysfunction (eg, increased response to irritants). Due to the chronic itch and reactivity, patients and parents of affected children will seek therapy. Therapies range from emollients to topical medicaments, including topical corticosteroids, and immunosuppressive agents. Due to concerns about the side effects of the available agents, patients and their loved ones will often seek "natural" agents as therapy. Oral agents that have been tried in (AD) include probiotics, vitamins, oils, and such traditional therapeutics as Chinese herbals and Ayurvedic agents. At this time probiotics may be promising, but there are inadequate data to determine their efficacy. In addition, there are significant concerns for the risks associated with Chinese herbals, which may be associated with liver failure and death, and Ayurvedic agents, which may be tainted with heavy metals. The safest and most effective natural agents are topically applied emollients. SN - 1879-1131 UR - https://www.unboundmedicine.com/medline/citation/30217278/Oral_supplements_in_atopic_dermatitis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0738-081X(18)30139-1 DB - PRIME DP - Unbound Medicine ER -