Tags

Type your tag names separated by a space and hit enter

[Correlation between ultrasonographic optic nerve sheath diameter and intracranial pressure].
Zhonghua Yan Ke Za Zhi 2018; 54(9):683-687ZY

Abstract

Objective:

To evaluate the association of the ultrasonographic optic nerve sheath diameter (ONSD) and intracranial pressure (ICP), and the feasibility of ultrasonographic ONSD in predicting high ICP.

Methods:

A prospective study. The outpatients who planned to measure ICP by lumbar puncture in Department of Neurology, Xuanwu Hospital, Capital Medical University were selected from January 2011 to May 2012. All the retrobulbar ONSD measurement with B-scan ultrasound was performed just before lumbar puncture. When high ICP was defined as ICP more than 200 mmH2O(1 mmH2O=0.009 8 kPa), the participants were divided into the high ICP group and the normal ICP group. The Pearson correlation coefficient analysis was used to analyze the correlation between ICP and postbulbar ONSD measurements. The difference in ONSD was compared between the high ICP and normal ICP groups with the t test. The receiver operating characteristic (ROC) curve was used to calculate the cutoff value of mean ONSD and evaluate the sensitivity and specificity of the method.

Results:

A total of 130 participants were involved in this study. There were 71 males and 59 females, aged (38±14) years.The mean ICP was (209.84±79.99) mmH2O. The mean ONSD was (5.68±0.78) mm in the right eyes, (5.78±0.78) mm in the left eyes, and (5.73±0.71) mm in both eyes. The ICP had a significant correlation with ONSD in the right eyes (r=0.54, P<0.001), ONSD in the left eyes (r=0.56, P<0.001) and ONSD in both eyes (r=0.60, P<0.001), but no correlation with age (r=-0.14, P=0.114) and gender (r=0.20, P=0.817). The ONSD in the high ICP group (n=65) was (6.11±0.66) mm, (6.22±0.56) mm and (6.17±0.50) mm in the right eyes, left eyes, and both eyes, respectively. Compared with the ONSD in the normal ICP group (n=65), which was (5.26±0.64) mm in the right eyes, (5.34±0.72) mm in the left eyes and (5.30±0.62) mm in both eyes, there was a significantly enlarged ONSD in the high ICP group (t=-7.507, -7.778, -8.779, all P<0.001). The ROC analysis showed the ONSD of 5.6 mm was the best cutoff value with a sensitivity of 86% and a specificity of 71% for identifying high ICP.

Conclusions:

There is a significantly positive correlation between ICP and postbulbar ONSD measured by ultrasound. This non-invasive method may be an alternative approach to predicting the ICP value of patients whose ICP measurement via lumbar puncture is at high risk. However, it can not replace the direct ICP measurement with the invasive method. (Chin J Ophthalmol, 2018, 54: 683-687).

Authors+Show Affiliations

Department of Ophthalmology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

chi

PubMed ID

30220184

Citation

Li, Z, et al. "[Correlation Between Ultrasonographic Optic Nerve Sheath Diameter and Intracranial Pressure]." [Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology, vol. 54, no. 9, 2018, pp. 683-687.
Li Z, Zhang XX, Yang HQ, et al. [Correlation between ultrasonographic optic nerve sheath diameter and intracranial pressure]. Zhonghua Yan Ke Za Zhi. 2018;54(9):683-687.
Li, Z., Zhang, X. X., Yang, H. Q., Zhao, L. P., Jia, J. P., Sun, F., & Liu, D. C. (2018). [Correlation between ultrasonographic optic nerve sheath diameter and intracranial pressure]. [Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology, 54(9), pp. 683-687. doi:10.3760/cma.j.issn.0412-4081.2018.09.009.
Li Z, et al. [Correlation Between Ultrasonographic Optic Nerve Sheath Diameter and Intracranial Pressure]. Zhonghua Yan Ke Za Zhi. 2018 Sep 11;54(9):683-687. PubMed PMID: 30220184.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Correlation between ultrasonographic optic nerve sheath diameter and intracranial pressure]. AU - Li,Z, AU - Zhang,X X, AU - Yang,H Q, AU - Zhao,L P, AU - Jia,J P, AU - Sun,F, AU - Liu,D C, PY - 2018/9/18/entrez PY - 2018/9/18/pubmed PY - 2019/6/27/medline KW - Intracranial pressure KW - Neurilemma KW - Optic nerve KW - Ultrasonography SP - 683 EP - 687 JF - [Zhonghua yan ke za zhi] Chinese journal of ophthalmology JO - Zhonghua Yan Ke Za Zhi VL - 54 IS - 9 N2 - Objective: To evaluate the association of the ultrasonographic optic nerve sheath diameter (ONSD) and intracranial pressure (ICP), and the feasibility of ultrasonographic ONSD in predicting high ICP. Methods: A prospective study. The outpatients who planned to measure ICP by lumbar puncture in Department of Neurology, Xuanwu Hospital, Capital Medical University were selected from January 2011 to May 2012. All the retrobulbar ONSD measurement with B-scan ultrasound was performed just before lumbar puncture. When high ICP was defined as ICP more than 200 mmH2O(1 mmH2O=0.009 8 kPa), the participants were divided into the high ICP group and the normal ICP group. The Pearson correlation coefficient analysis was used to analyze the correlation between ICP and postbulbar ONSD measurements. The difference in ONSD was compared between the high ICP and normal ICP groups with the t test. The receiver operating characteristic (ROC) curve was used to calculate the cutoff value of mean ONSD and evaluate the sensitivity and specificity of the method. Results: A total of 130 participants were involved in this study. There were 71 males and 59 females, aged (38±14) years.The mean ICP was (209.84±79.99) mmH2O. The mean ONSD was (5.68±0.78) mm in the right eyes, (5.78±0.78) mm in the left eyes, and (5.73±0.71) mm in both eyes. The ICP had a significant correlation with ONSD in the right eyes (r=0.54, P<0.001), ONSD in the left eyes (r=0.56, P<0.001) and ONSD in both eyes (r=0.60, P<0.001), but no correlation with age (r=-0.14, P=0.114) and gender (r=0.20, P=0.817). The ONSD in the high ICP group (n=65) was (6.11±0.66) mm, (6.22±0.56) mm and (6.17±0.50) mm in the right eyes, left eyes, and both eyes, respectively. Compared with the ONSD in the normal ICP group (n=65), which was (5.26±0.64) mm in the right eyes, (5.34±0.72) mm in the left eyes and (5.30±0.62) mm in both eyes, there was a significantly enlarged ONSD in the high ICP group (t=-7.507, -7.778, -8.779, all P<0.001). The ROC analysis showed the ONSD of 5.6 mm was the best cutoff value with a sensitivity of 86% and a specificity of 71% for identifying high ICP. Conclusions: There is a significantly positive correlation between ICP and postbulbar ONSD measured by ultrasound. This non-invasive method may be an alternative approach to predicting the ICP value of patients whose ICP measurement via lumbar puncture is at high risk. However, it can not replace the direct ICP measurement with the invasive method. (Chin J Ophthalmol, 2018, 54: 683-687). SN - 0412-4081 UR - https://www.unboundmedicine.com/medline/citation/30220184/[Correlation_between_ultrasonographic_optic_nerve_sheath_diameter_and_intracranial_pressure]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&amp;issn=0412-4081&amp;year=2018&amp;vol=54&amp;issue=9&amp;fpage=683 DB - PRIME DP - Unbound Medicine ER -