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Effect of Nitrous Oxide on Pulpal Anesthesia: A Preliminary Study.
Anesth Prog 2018; 65(3):156-161AP

Abstract

To compare the success of perceived pulpal anesthesia between groups using nitrous oxide/oxygen (N2O/O2) and oxygen (O2) in children premedicated with ibuprofen with symptomatic irreversible pulpitis permanent teeth. Thirty-three children (mean age 10.4 ± 1.9 years) with 33 symptomatic irreversible pulpitis permanent teeth were included in this preliminary study. All children were premedicated with ibuprofen and randomly assigned to receive either N2O/O2 (17 participants) or O2 (16 participants). Four percent articaine with epinephrine 1:100,000 was administered, and vital pulp therapy was performed. Children used the Wong-Baker FACES Pain Rating Scale (WBFPS) to report their pain at baseline as well as during carious dentin removal, pulpal exposure, and pulpal tissue removal steps. The success was determined when the reported WBFPS score was ≤4. The chi-square test was used to compare the success between both groups. The success of pulpal anesthesia was 71% (12/17) and 19% (3/16) in the N2O/O2 and O2 groups, respectively. The success in the N2O/O2 group was 52% higher than that in the O2 group (confidence interval = 22.9% to 80.7%; significant difference p = .003). From the result of this preliminary study, N2O/O2 significantly increased the success of perceived pulpal anesthesia in children premedicated with ibuprofen with symptomatic irreversible pulpitis permanent teeth. However, further study with a larger sample is required to confirm this result.

Authors+Show Affiliations

Division of Pediatric Dentistry, Department of Orthodontics and Pediatric Dentistry, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.Former postgraduate student in pediatric dentistry, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.Department of Family and Community Dentistry, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.Department of Family and Community Dentistry, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.Dental Research Center, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.Division of Endodontics, Department of Restorative Dentistry and Periodontology, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

30235437

Citation

Chompu-Inwai, Papimon, et al. "Effect of Nitrous Oxide On Pulpal Anesthesia: a Preliminary Study." Anesthesia Progress, vol. 65, no. 3, 2018, pp. 156-161.
Chompu-Inwai P, Simprasert S, Chuveera P, et al. Effect of Nitrous Oxide on Pulpal Anesthesia: A Preliminary Study. Anesth Prog. 2018;65(3):156-161.
Chompu-Inwai, P., Simprasert, S., Chuveera, P., Nirunsittirat, A., Sastraruji, T., & Srisuwan, T. (2018). Effect of Nitrous Oxide on Pulpal Anesthesia: A Preliminary Study. Anesthesia Progress, 65(3), pp. 156-161. doi:10.2344/anpr-65-02-08.
Chompu-Inwai P, et al. Effect of Nitrous Oxide On Pulpal Anesthesia: a Preliminary Study. Anesth Prog. 2018;65(3):156-161. PubMed PMID: 30235437.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of Nitrous Oxide on Pulpal Anesthesia: A Preliminary Study. AU - Chompu-Inwai,Papimon, AU - Simprasert,Sophon, AU - Chuveera,Patchanee, AU - Nirunsittirat,Areerat, AU - Sastraruji,Thanapat, AU - Srisuwan,Tanida, PY - 2018/9/21/entrez PY - 2018/9/21/pubmed PY - 2019/10/8/medline KW - Ibuprofen. KW - Nitrous oxide KW - Pulpal anesthesia KW - Symptomatic irreversible pulpitis SP - 156 EP - 161 JF - Anesthesia progress JO - Anesth Prog VL - 65 IS - 3 N2 - To compare the success of perceived pulpal anesthesia between groups using nitrous oxide/oxygen (N2O/O2) and oxygen (O2) in children premedicated with ibuprofen with symptomatic irreversible pulpitis permanent teeth. Thirty-three children (mean age 10.4 ± 1.9 years) with 33 symptomatic irreversible pulpitis permanent teeth were included in this preliminary study. All children were premedicated with ibuprofen and randomly assigned to receive either N2O/O2 (17 participants) or O2 (16 participants). Four percent articaine with epinephrine 1:100,000 was administered, and vital pulp therapy was performed. Children used the Wong-Baker FACES Pain Rating Scale (WBFPS) to report their pain at baseline as well as during carious dentin removal, pulpal exposure, and pulpal tissue removal steps. The success was determined when the reported WBFPS score was ≤4. The chi-square test was used to compare the success between both groups. The success of pulpal anesthesia was 71% (12/17) and 19% (3/16) in the N2O/O2 and O2 groups, respectively. The success in the N2O/O2 group was 52% higher than that in the O2 group (confidence interval = 22.9% to 80.7%; significant difference p = .003). From the result of this preliminary study, N2O/O2 significantly increased the success of perceived pulpal anesthesia in children premedicated with ibuprofen with symptomatic irreversible pulpitis permanent teeth. However, further study with a larger sample is required to confirm this result. SN - 1878-7177 UR - https://www.unboundmedicine.com/medline/citation/30235437/Effect_of_Nitrous_Oxide_on_Pulpal_Anesthesia:_A_Preliminary_Study L2 - http://www.anesthesiaprogress.org/doi/10.2344/anpr-65-02-08?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -