Tags

Type your tag names separated by a space and hit enter

Enantioselective toxic effects and digestion of furalaxyl enantiomers in Scenedesmus obliquus.
Chirality. 2018 12; 30(12):1269-1276.C

Abstract

Research on the enantioselective environmental behavior of chiral pesticides has been a hot spot of environmental chemistry recently. In this study, the acute toxicity and digestion of furalaxyl enantiomers were determined on the aquatic algae Scendesmus obliquus. After exposure for 96 hours, the EC50 values for (S)-furalaxyl and (R)-furalaxyl were 13.59 and 15.26 mg/L, respectively. In addition, enantioselectivity was observed from the determined chlorophyll contents and antioxidant enzyme (CAT and SOD) activities of algae cells after exposure to furalaxyl enantiomers for 96 hours. The digestion rate of (S)-furalaxyl and (R)-furalaxyl were almost the same in S. obliquus. On the basis of these data, the inactive enantiomers (S)- furalaxyl is more toxic than the active one on the non-target species S. obliquus, indicating that such enantiomeric differences should be taken into consideration in the study of pesticide risk assessment.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

College of Science, China Agricultural University, Beijing, China.

College of Science, China Agricultural University, Beijing, China.

College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.

College of Science, China Agricultural University, Beijing, China.

College of Science, China Agricultural University, Beijing, China.

College of Science, China Agricultural University, Beijing, China.

College of Science, China Agricultural University, Beijing, China.

College of Science, China Agricultural University, Beijing, China.

College of Science, China Agricultural University, Beijing, China.

College of Science, China Agricultural University, Beijing, China.

MeSH

AntioxidantsCatalaseChlorophyllEcotoxicologyFungicides, IndustrialFuransScenedesmusStereoisomerismSuperoxide DismutaseToxicity Tests, Acute

Pub Type(s)

Journal Article

Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

30238504

Citation

Cheng, Cheng, et al. "Enantioselective Toxic Effects and Digestion of Furalaxyl Enantiomers in Scenedesmus Obliquus." Chirality, vol. 30, no. 12, 2018, pp. 1269-1276.

Cheng C, Ma R, Lu Y, et al. Enantioselective toxic effects and digestion of furalaxyl enantiomers in Scenedesmus obliquus. Chirality. 2018;30(12):1269-1276.

Cheng, C., Ma, R., Lu, Y., Liu, C., Zhang, W., Di, S., Chen, L., Diao, J., Zhou, Z., & Hou, Y. (2018). Enantioselective toxic effects and digestion of furalaxyl enantiomers in Scenedesmus obliquus. Chirality, 30(12), 1269-1276. https://doi.org/10.1002/chir.23020

Cheng C, et al. Enantioselective Toxic Effects and Digestion of Furalaxyl Enantiomers in Scenedesmus Obliquus. Chirality. 2018;30(12):1269-1276. PubMed PMID: 30238504.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Enantioselective toxic effects and digestion of furalaxyl enantiomers in Scenedesmus obliquus. AU - Cheng,Cheng, AU - Ma,Rui, AU - Lu,Yuele, AU - Liu,Chunxiao, AU - Zhang,Wenjun, AU - Di,Shanshan, AU - Chen,Li, AU - Diao,Jinling, AU - Zhou,Zhiqiang, AU - Hou,Yuxia, Y1 - 2018/09/20/ PY - 2018/04/03/received PY - 2018/05/27/revised PY - 2018/08/30/accepted PY - 2018/9/22/pubmed PY - 2019/8/30/medline PY - 2018/9/22/entrez KW - Scendesmus obliquus KW - antioxidant enzyme (CAT, SOD) activity KW - chlorophyll KW - digestion KW - furalaxyl enantiomers SP - 1269 EP - 1276 JF - Chirality JO - Chirality VL - 30 IS - 12 N2 - Research on the enantioselective environmental behavior of chiral pesticides has been a hot spot of environmental chemistry recently. In this study, the acute toxicity and digestion of furalaxyl enantiomers were determined on the aquatic algae Scendesmus obliquus. After exposure for 96 hours, the EC50 values for (S)-furalaxyl and (R)-furalaxyl were 13.59 and 15.26 mg/L, respectively. In addition, enantioselectivity was observed from the determined chlorophyll contents and antioxidant enzyme (CAT and SOD) activities of algae cells after exposure to furalaxyl enantiomers for 96 hours. The digestion rate of (S)-furalaxyl and (R)-furalaxyl were almost the same in S. obliquus. On the basis of these data, the inactive enantiomers (S)- furalaxyl is more toxic than the active one on the non-target species S. obliquus, indicating that such enantiomeric differences should be taken into consideration in the study of pesticide risk assessment. SN - 1520-636X UR - https://www.unboundmedicine.com/medline/citation/30238504/Enantioselective_toxic_effects_and_digestion_of_furalaxyl_enantiomers_in_Scenedesmus_obliquus_ DB - PRIME DP - Unbound Medicine ER -