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Oral Cryotherapy: Prevention of Oral Mucositis and Pain Among Patients With Colorectal Cancer Undergoing Chemotherapy.
Clin J Oncol Nurs. 2018 10 01; 22(5):555-560.CJ

Abstract

BACKGROUND

Evidence remains mixed on the benefits of oral cryotherapy in the prevention of oral mucositis and pain associated with fluorouracil-based chemotherapy.

OBJECTIVES

The intent of this article is to evaluate the effect of oral cryotherapy on the prevention of oral mucositis and pain among patients with colorectal cancer undergoing fluorouracil-based chemotherapy.

METHODS

Using an experimental study design, the authors randomly assigned 80 patients to either the intervention (n = 40) or usual care group (n = 40). Intervention group participants received oral cryotherapy in the form of ice chips held in their mouths during chemotherapy infusion. Both groups used sodium bicarbonate mouthwash postchemotherapy until the next cycle.

FINDINGS

In the usual care group, most participants reported grade 2 (moderate to life-threatening) or greater mucositis. Pain associated with mucositis was lower using oral cryotherapy, with the majority of participants in the intervention group reporting no pain.

Authors+Show Affiliations

Sungai Buloh Allied Health Science College.University of Malaya.University of Malaya Medical Centre.National University of Malaysia.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30239519

Citation

Idayu Mat Nawi, Ros, et al. "Oral Cryotherapy: Prevention of Oral Mucositis and Pain Among Patients With Colorectal Cancer Undergoing Chemotherapy." Clinical Journal of Oncology Nursing, vol. 22, no. 5, 2018, pp. 555-560.
Idayu Mat Nawi R, Lei Chui P, Wan Ishak WZ, et al. Oral Cryotherapy: Prevention of Oral Mucositis and Pain Among Patients With Colorectal Cancer Undergoing Chemotherapy. Clin J Oncol Nurs. 2018;22(5):555-560.
Idayu Mat Nawi, R., Lei Chui, P., Wan Ishak, W. Z., & Hsien Chan, C. M. (2018). Oral Cryotherapy: Prevention of Oral Mucositis and Pain Among Patients With Colorectal Cancer Undergoing Chemotherapy. Clinical Journal of Oncology Nursing, 22(5), 555-560. https://doi.org/10.1188/18.CJON.555-560
Idayu Mat Nawi R, et al. Oral Cryotherapy: Prevention of Oral Mucositis and Pain Among Patients With Colorectal Cancer Undergoing Chemotherapy. Clin J Oncol Nurs. 2018 10 1;22(5):555-560. PubMed PMID: 30239519.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oral Cryotherapy: Prevention of Oral Mucositis and Pain Among Patients With Colorectal Cancer Undergoing Chemotherapy. AU - Idayu Mat Nawi,Ros, AU - Lei Chui,Ping, AU - Wan Ishak,Wan Zamaniah, AU - Hsien Chan,Caryn Mei, PY - 2018/9/22/entrez PY - 2018/9/22/pubmed PY - 2019/8/6/medline KW - cancer KW - chemotherapy KW - ice chips KW - mucositis KW - oral care KW - oral cryotherapy KW - pain SP - 555 EP - 560 JF - Clinical journal of oncology nursing JO - Clin J Oncol Nurs VL - 22 IS - 5 N2 - BACKGROUND: Evidence remains mixed on the benefits of oral cryotherapy in the prevention of oral mucositis and pain associated with fluorouracil-based chemotherapy. OBJECTIVES: The intent of this article is to evaluate the effect of oral cryotherapy on the prevention of oral mucositis and pain among patients with colorectal cancer undergoing fluorouracil-based chemotherapy. METHODS: Using an experimental study design, the authors randomly assigned 80 patients to either the intervention (n = 40) or usual care group (n = 40). Intervention group participants received oral cryotherapy in the form of ice chips held in their mouths during chemotherapy infusion. Both groups used sodium bicarbonate mouthwash postchemotherapy until the next cycle. FINDINGS: In the usual care group, most participants reported grade 2 (moderate to life-threatening) or greater mucositis. Pain associated with mucositis was lower using oral cryotherapy, with the majority of participants in the intervention group reporting no pain. SN - 1538-067X UR - https://www.unboundmedicine.com/medline/citation/30239519/Oral_Cryotherapy:_Prevention_of_Oral_Mucositis_and_Pain_Among_Patients_With_Colorectal_Cancer_Undergoing_Chemotherapy_ L2 - http://store.ons.org/article/find?doi=10.1188/18.CJON.555-560 DB - PRIME DP - Unbound Medicine ER -