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Spontaneous Giant Laryngeal Granuloma in the Absence of Laryngeal Injury.
J Voice. 2020 Jan; 34(1):162.e1-162.e3.JV

Abstract

The etiology of laryngeal granuloma can typically be attributed to endotracheal intubation, vocal abuse, or gastroesophageal reflux disease. There is a strong male predominance, except in cases due to intubation, where incidence is higher in women. We report a case of spontaneous development of multiple granulomas in a female with no history of intubation who presented with hoarseness and massive bilateral supraglottic masses obscuring her glottis. The disparity between the massive lesions and asymptomatic reflux highlights the need for further research in the pathophysiology of laryngeal granulomas.

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Authors+Show Affiliations

Shah RR
Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA.
Mirza NA
Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA. Electronic address: natasha.mirza@mail.med.upenn.edu.

MeSH

AgedFemaleGranuloma, LaryngealHoarsenessHumansLaryngoscopyTreatment OutcomeVoice Quality

Pub Type(s)

Case Reports

Language

eng

PubMed ID

30243668

Citation

Shah, Ravi R., and Natasha A. Mirza. "Spontaneous Giant Laryngeal Granuloma in the Absence of Laryngeal Injury." Journal of Voice : Official Journal of the Voice Foundation, vol. 34, no. 1, 2020, pp. 162.e1-162.e3.
Shah RR, Mirza NA. Spontaneous Giant Laryngeal Granuloma in the Absence of Laryngeal Injury. J Voice. 2020;34(1):162.e1-162.e3.
Shah, R. R., & Mirza, N. A. (2020). Spontaneous Giant Laryngeal Granuloma in the Absence of Laryngeal Injury. Journal of Voice : Official Journal of the Voice Foundation, 34(1), e1-e3. https://doi.org/10.1016/j.jvoice.2018.08.013
Shah RR, Mirza NA. Spontaneous Giant Laryngeal Granuloma in the Absence of Laryngeal Injury. J Voice. 2020;34(1):162.e1-162.e3. PubMed PMID: 30243668.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Spontaneous Giant Laryngeal Granuloma in the Absence of Laryngeal Injury. AU - Shah,Ravi R, AU - Mirza,Natasha A, Y1 - 2018/09/20/ PY - 2018/06/17/received PY - 2018/08/20/revised PY - 2018/08/22/accepted PY - 2018/9/24/pubmed PY - 2020/11/18/medline PY - 2018/9/24/entrez KW - Gastroesophageal reflux KW - Hoarseness KW - Intubation KW - Laryngeal granuloma KW - Supraglottic mass SP - 162.e1 EP - 162.e3 JF - Journal of voice : official journal of the Voice Foundation JO - J Voice VL - 34 IS - 1 N2 - The etiology of laryngeal granuloma can typically be attributed to endotracheal intubation, vocal abuse, or gastroesophageal reflux disease. There is a strong male predominance, except in cases due to intubation, where incidence is higher in women. We report a case of spontaneous development of multiple granulomas in a female with no history of intubation who presented with hoarseness and massive bilateral supraglottic masses obscuring her glottis. The disparity between the massive lesions and asymptomatic reflux highlights the need for further research in the pathophysiology of laryngeal granulomas. SN - 1873-4588 UR - https://www.unboundmedicine.com/medline/citation/30243668/Spontaneous_Giant_Laryngeal_Granuloma_in_the_Absence_of_Laryngeal_Injury_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0892-1997(18)30265-0 DB - PRIME DP - Unbound Medicine ER -