Tags

Type your tag names separated by a space and hit enter

Differential transmission of Asian and African Zika virus lineages by Aedes aegypti from New Caledonia.
Emerg Microbes Infect. 2018 Sep 26; 7(1):159.EM

Abstract

Zika virus (ZIKV) is a Flavivirus that is transmitted to humans by Aedes mosquitoes. ZIKV is divided into two phylogenetic lineages, African and Asian. In the Asian lineage, Pacific and American clades have been linked to the recent worldwide outbreak of ZIKV. The aim of this study was to measure the vector competence of Aedes aegypti for seven ZIKV strains belonging to both lineages. We demonstrate that Ae. aegypti from New Caledonia (NC), South Pacific region, is a low-competence vector for Asian ZIKV (<10% transmission efficiency). No significant differences were observed in vector competence with respect to the sampling date and collection site of Asian ZIKV strains used (2014 and 2015 for New Caledonia, Pacific clade, and 2016 for French Guiana, American clade). The ability of the New Caledonian Ae. aegypti to transmit ZIKV is significantly greater for the earlier viral isolates belonging to the African lineage (>37% transmission efficiency after 9 days post-infection) compared to recent ZIKV isolates from African (10% transmission efficiency) and Asian lineages (<10% transmission efficiency). The results of this study demonstrate that Ae. aegypti from NC can become infected and replicate different ZIKV strains belonging to all lineages. Our data emphasize the importance of studying the interaction between vectors and their arboviruses according to each local geographic context. This approach will improve our understanding of arbovirus transmission to prevent their emergence and improve health surveillance.

Authors+Show Affiliations

Institut Pasteur de Nouvelle-Calédonie, URE-Dengue et autres Arboviroses, Réseau International des Institut Pasteur, Nouméa, New Caledonia.Institut Pasteur de Nouvelle-Calédonie, URE-Dengue et autres Arboviroses, Réseau International des Institut Pasteur, Nouméa, New Caledonia.Institut Pasteur de Nouvelle-Calédonie, URE-Entomologie Médicale, Institut Pasteur de Nouvelle-Calédonie, Réseau International des Institut Pasteur, Noumea, New Caledonia.Institut Pasteur de la Guyane, Laboratoire de Virologie, Centre National de Référence des arbovirus, Réseau International des Institut Pasteur, Cayenne, French Guiana.Institut Pasteur de Dakar, Unité Arbovirus et Virus des Fièvres Hémorragiques, Réseau International des Institut Pasteur, Dakar, Senegal.Institut Pasteur de Nouvelle-Calédonie, Direction, Réseau International des Institut Pasteur, Nouméa, New Caledonia.Institut Pasteur de Nouvelle-Calédonie, Unité Epidémiologie, Réseau International des Institut Pasteur, Nouméa, New Caledonia.Institut Pasteur de Nouvelle-Calédonie, URE-Dengue et autres Arboviroses, Réseau International des Institut Pasteur, Nouméa, New Caledonia. mdupont@pasteur.nc.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30254274

Citation

Calvez, Elodie, et al. "Differential Transmission of Asian and African Zika Virus Lineages By Aedes Aegypti From New Caledonia." Emerging Microbes & Infections, vol. 7, no. 1, 2018, p. 159.
Calvez E, O'Connor O, Pol M, et al. Differential transmission of Asian and African Zika virus lineages by Aedes aegypti from New Caledonia. Emerg Microbes Infect. 2018;7(1):159.
Calvez, E., O'Connor, O., Pol, M., Rousset, D., Faye, O., Richard, V., Tarantola, A., & Dupont-Rouzeyrol, M. (2018). Differential transmission of Asian and African Zika virus lineages by Aedes aegypti from New Caledonia. Emerging Microbes & Infections, 7(1), 159. https://doi.org/10.1038/s41426-018-0166-2
Calvez E, et al. Differential Transmission of Asian and African Zika Virus Lineages By Aedes Aegypti From New Caledonia. Emerg Microbes Infect. 2018 Sep 26;7(1):159. PubMed PMID: 30254274.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Differential transmission of Asian and African Zika virus lineages by Aedes aegypti from New Caledonia. AU - Calvez,Elodie, AU - O'Connor,Olivia, AU - Pol,Morgane, AU - Rousset,Dominique, AU - Faye,Oumar, AU - Richard,Vincent, AU - Tarantola,Arnaud, AU - Dupont-Rouzeyrol,Myrielle, Y1 - 2018/09/26/ PY - 2018/03/05/received PY - 2018/08/29/accepted PY - 2018/08/29/revised PY - 2018/9/27/entrez PY - 2018/9/27/pubmed PY - 2019/1/23/medline SP - 159 EP - 159 JF - Emerging microbes & infections JO - Emerg Microbes Infect VL - 7 IS - 1 N2 - Zika virus (ZIKV) is a Flavivirus that is transmitted to humans by Aedes mosquitoes. ZIKV is divided into two phylogenetic lineages, African and Asian. In the Asian lineage, Pacific and American clades have been linked to the recent worldwide outbreak of ZIKV. The aim of this study was to measure the vector competence of Aedes aegypti for seven ZIKV strains belonging to both lineages. We demonstrate that Ae. aegypti from New Caledonia (NC), South Pacific region, is a low-competence vector for Asian ZIKV (<10% transmission efficiency). No significant differences were observed in vector competence with respect to the sampling date and collection site of Asian ZIKV strains used (2014 and 2015 for New Caledonia, Pacific clade, and 2016 for French Guiana, American clade). The ability of the New Caledonian Ae. aegypti to transmit ZIKV is significantly greater for the earlier viral isolates belonging to the African lineage (>37% transmission efficiency after 9 days post-infection) compared to recent ZIKV isolates from African (10% transmission efficiency) and Asian lineages (<10% transmission efficiency). The results of this study demonstrate that Ae. aegypti from NC can become infected and replicate different ZIKV strains belonging to all lineages. Our data emphasize the importance of studying the interaction between vectors and their arboviruses according to each local geographic context. This approach will improve our understanding of arbovirus transmission to prevent their emergence and improve health surveillance. SN - 2222-1751 UR - https://www.unboundmedicine.com/medline/citation/30254274/Differential_transmission_of_Asian_and_African_Zika_virus_lineages_by_Aedes_aegypti_from_New_Caledonia_ L2 - http://dx.doi.org/10.1038/s41426-018-0166-2 DB - PRIME DP - Unbound Medicine ER -