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Clear Cell Acanthoma on the Areola.
Dermatol Online J. 2018 Jul 15; 24(7)DO

Abstract

Clear cell acanthoma (CCA) is a rare, benign cutaneous condition most often seen on the lower extremities. Lesions are of variable morphology and have been described as polypoid, pigmented, giant, and cystic lesions. Although no racial or gender predilection has been reported, CCA on the breast is a very rare finding that has been observed mainly in young Korean women. Herein, we describe a case of CCA of the areola in an elderly woman with metastatic renal cell carcinoma. Physical exam revealed a pink plaque with central erosions on the left areola. Given the concern for cutaneous metastasis, excisional biopsy was performed, which showed pale glycogenated epithelium consistent with CCA. No evidence of recurrence or new lesions was observed after 6 months of follow-up. Our case exemplifies that clinicians should consider CCA in the differential diagnosis for a new eczematous lesion involving the breast, even in the setting of malignancy.

Authors+Show Affiliations

No affiliation info availableNo affiliation info availableNo affiliation info availableDepartment of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida. hlevtov@med.miami.edu.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

30261576

Citation

Borda, Luis J., et al. "Clear Cell Acanthoma On the Areola." Dermatology Online Journal, vol. 24, no. 7, 2018.
Borda LJ, Mervis JS, Romanelli P, et al. Clear Cell Acanthoma on the Areola. Dermatol Online J. 2018;24(7).
Borda, L. J., Mervis, J. S., Romanelli, P., & Lev-Tov, H. (2018). Clear Cell Acanthoma on the Areola. Dermatology Online Journal, 24(7).
Borda LJ, et al. Clear Cell Acanthoma On the Areola. Dermatol Online J. 2018 Jul 15;24(7) PubMed PMID: 30261576.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clear Cell Acanthoma on the Areola. AU - Borda,Luis J, AU - Mervis,Joshua S, AU - Romanelli,Paolo, AU - Lev-Tov,Hadar, Y1 - 2018/07/15/ PY - 2018/09/12/received PY - 2018/09/12/accepted PY - 2018/9/29/entrez PY - 2018/9/29/pubmed PY - 2019/1/27/medline JF - Dermatology online journal JO - Dermatol. Online J. VL - 24 IS - 7 N2 - Clear cell acanthoma (CCA) is a rare, benign cutaneous condition most often seen on the lower extremities. Lesions are of variable morphology and have been described as polypoid, pigmented, giant, and cystic lesions. Although no racial or gender predilection has been reported, CCA on the breast is a very rare finding that has been observed mainly in young Korean women. Herein, we describe a case of CCA of the areola in an elderly woman with metastatic renal cell carcinoma. Physical exam revealed a pink plaque with central erosions on the left areola. Given the concern for cutaneous metastasis, excisional biopsy was performed, which showed pale glycogenated epithelium consistent with CCA. No evidence of recurrence or new lesions was observed after 6 months of follow-up. Our case exemplifies that clinicians should consider CCA in the differential diagnosis for a new eczematous lesion involving the breast, even in the setting of malignancy. SN - 1087-2108 UR - https://www.unboundmedicine.com/medline/citation/30261576/Clear_Cell_Acanthoma_on_the_Areola L2 - http://escholarship.org/uc/item/9q47d056 DB - PRIME DP - Unbound Medicine ER -