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Multiple myeloma with pathologically proven skull plasmacytoma after a mild head injury: Case report.
Medicine (Baltimore). 2018 Sep; 97(39):e12327.M

Abstract

RATIONALE

MM is a malignant tumor originating from the plasma cells of the bone marrow. Central nervous system myelomatosis is very rare and may be a complication of MM.

PATIENT CONCERNS

A 60-year-old man presented with a slowly growing soft mass at his right frontal scalp after a mild head injury 6 months ago.

DIAGNOSES

Neuroradiological examinations revealed a solid intracranial-extracranial mass with an osteolytic lesion in the skull. Histopathological examination showed skull plasmacytoma, and postoperative examinations revealed multiple myeloma.

INTERVENTIONS

The tumor was completely removed and the skull defect repaired with the titanium mesh. Then, chemotherapy was initiated after surgery with bortezomib and dexamethasone.

OUTCOMES

The patient received eight chemotherapies within one year after surgery.

LESSONS

Despite a history of head injury, a differential diagnosis should be kept in mind during the diagnosis of solid intracranial-extracranial masses, especially in the presence of osteolytic skull at the lesioned site.

Authors+Show Affiliations

Department of Neurosurgery, the 2nd Hospital of Lanzhou University.Gynecology Department, Maternity and Child Care Hospital of Gansu Province, Lanzhou, Gansu Province, China.Department of Neurosurgery, the 2nd Hospital of Lanzhou University.Department of Neurosurgery, the 2nd Hospital of Lanzhou University.Department of Neurosurgery, the 2nd Hospital of Lanzhou University.Department of Neurosurgery, the 2nd Hospital of Lanzhou University.Department of Neurosurgery, the 2nd Hospital of Lanzhou University.Department of Neurosurgery, the 2nd Hospital of Lanzhou University.Department of Neurosurgery, the 2nd Hospital of Lanzhou University.Department of Neurosurgery, the 2nd Hospital of Lanzhou University.Department of Neurosurgery, the 2nd Hospital of Lanzhou University.Department of Neurosurgery, the 2nd Hospital of Lanzhou University.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

30278508

Citation

Yang, Wenzhen, et al. "Multiple Myeloma With Pathologically Proven Skull Plasmacytoma After a Mild Head Injury: Case Report." Medicine, vol. 97, no. 39, 2018, pp. e12327.
Yang W, Zheng J, Li R, et al. Multiple myeloma with pathologically proven skull plasmacytoma after a mild head injury: Case report. Medicine (Baltimore). 2018;97(39):e12327.
Yang, W., Zheng, J., Li, R., Ren, H., Hou, B., Zhao, Z., Wang, D., Wang, G., Liu, J., Yan, G., Wang, D., & Zhang, X. (2018). Multiple myeloma with pathologically proven skull plasmacytoma after a mild head injury: Case report. Medicine, 97(39), e12327. https://doi.org/10.1097/MD.0000000000012327
Yang W, et al. Multiple Myeloma With Pathologically Proven Skull Plasmacytoma After a Mild Head Injury: Case Report. Medicine (Baltimore). 2018;97(39):e12327. PubMed PMID: 30278508.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Multiple myeloma with pathologically proven skull plasmacytoma after a mild head injury: Case report. AU - Yang,Wenzhen, AU - Zheng,Jing, AU - Li,Ruihao, AU - Ren,Haijun, AU - Hou,Boru, AU - Zhao,Zhiyong, AU - Wang,Dengfeng, AU - Wang,Gang, AU - Liu,Jixing, AU - Yan,Guizhong, AU - Wang,Dong, AU - Zhang,Xinding, PY - 2018/10/4/entrez PY - 2018/10/4/pubmed PY - 2018/10/13/medline SP - e12327 EP - e12327 JF - Medicine JO - Medicine (Baltimore) VL - 97 IS - 39 N2 - RATIONALE: MM is a malignant tumor originating from the plasma cells of the bone marrow. Central nervous system myelomatosis is very rare and may be a complication of MM. PATIENT CONCERNS: A 60-year-old man presented with a slowly growing soft mass at his right frontal scalp after a mild head injury 6 months ago. DIAGNOSES: Neuroradiological examinations revealed a solid intracranial-extracranial mass with an osteolytic lesion in the skull. Histopathological examination showed skull plasmacytoma, and postoperative examinations revealed multiple myeloma. INTERVENTIONS: The tumor was completely removed and the skull defect repaired with the titanium mesh. Then, chemotherapy was initiated after surgery with bortezomib and dexamethasone. OUTCOMES: The patient received eight chemotherapies within one year after surgery. LESSONS: Despite a history of head injury, a differential diagnosis should be kept in mind during the diagnosis of solid intracranial-extracranial masses, especially in the presence of osteolytic skull at the lesioned site. SN - 1536-5964 UR - https://www.unboundmedicine.com/medline/citation/30278508/Multiple_myeloma_with_pathologically_proven_skull_plasmacytoma_after_a_mild_head_injury:_Case_report_ L2 - http://dx.doi.org/10.1097/MD.0000000000012327 DB - PRIME DP - Unbound Medicine ER -