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Effect of Liuzijue Qigong on patients with chronic obstructive pulmonary disease: Protocol for a systematic review and meta-analysis.
Medicine (Baltimore) 2018; 97(40):e12659M

Abstract

BACKGROUND

Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide with a substantial and increasing social and economic burden. Liuzijue Qigong is a kind of traditional Chinese Qigong exercises that Traditional Chinese Medicine practitioners prescribe to individuals with COPD to strengthen the internal organs' function. Liuzijue Qigong was recommended for use in COPD rehabilitation, and some clinical trials indicate that Liuzijue Qigong would produce better functional capacity and quality of life of individuals with COPD. The objective of this study is to conduct a systematic review of the existing studies to assess effectiveness and safety of Liuzijue Qigong for the prevention or treatment of COPD in patients.

METHODS

We will perform the comprehensive literature search in English and Chinese electronic database. The publication period will be from inception to the search date. In addition, the clinical trial registries, dissertations, informal publication, grey literature, reference lists of studies, systematic reviews, and conference abstracts will also be collected. Two reviewers will identify relevant studies, extract data information, and then assess the methodical quality by the Cochrane risk of bias assessment tool. Only randomized controlled trials comparing Liuzijue Qigong against other intervention or nonintervention will be included. Data will be synthesized by either fixed-effect or random-effect model regarding to a heterogeneity test. The routine lung function, arterial blood gas tensions, partial pressure of carbon dioxide, functional capacity, 30 seconds sit-to-stand test, respiratory function, maximal inspiration pressure, maximal expiratory pressure, airway resistance, and specific airway conductance will be assessed as primary outcomes. The secondary outcomes involved dyspnea, and fatigue levels, respiratory muscle strength, upper and lower limb muscle strength, handgrip strength test, and health-related quality of life and safety. Meta-analysis will be performed by using Cochrane's Review Manager software (version 5.3.5).

RESULTS

This systematic review and meta-analysis will provide a high-quality synthesis and evaluate the efficacy and safety based on current relevant literature evidence of Liuzijue Qigong intervention for COPD patient.

CONCLUSION

Our systematic review will provide evidence to determine whether Liuzijue Qigong is an effective and safe approach to prevention and treatment of COPD patients.

Authors+Show Affiliations

School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing. Ovation Health Science and Technology Co. Ltd, ENN Group, Langfang.School of Acupuncture-Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu.Department of Ophthalmology, China-Japan Friendship Hospital, Beijing, China.Ovation Health Science and Technology Co. Ltd, ENN Group, Langfang.School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing. Ovation Health Science and Technology Co. Ltd, ENN Group, Langfang.School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing.School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing. Ovation Health Science and Technology Co. Ltd, ENN Group, Langfang.School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing. Ovation Health Science and Technology Co. Ltd, ENN Group, Langfang.School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing.Ovation Health Science and Technology Co. Ltd, ENN Group, Langfang.School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing.School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing.School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing.

Pub Type(s)

Journal Article
Meta-Analysis

Language

eng

PubMed ID

30290646

Citation

Guo, Yu, et al. "Effect of Liuzijue Qigong On Patients With Chronic Obstructive Pulmonary Disease: Protocol for a Systematic Review and Meta-analysis." Medicine, vol. 97, no. 40, 2018, pp. e12659.
Guo Y, Xu M, Ji M, et al. Effect of Liuzijue Qigong on patients with chronic obstructive pulmonary disease: Protocol for a systematic review and meta-analysis. Medicine (Baltimore). 2018;97(40):e12659.
Guo, Y., Xu, M., Ji, M., Zhang, J., Hu, Q., Wei, Z., ... Wei, Y. (2018). Effect of Liuzijue Qigong on patients with chronic obstructive pulmonary disease: Protocol for a systematic review and meta-analysis. Medicine, 97(40), pp. e12659. doi:10.1097/MD.0000000000012659.
Guo Y, et al. Effect of Liuzijue Qigong On Patients With Chronic Obstructive Pulmonary Disease: Protocol for a Systematic Review and Meta-analysis. Medicine (Baltimore). 2018;97(40):e12659. PubMed PMID: 30290646.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of Liuzijue Qigong on patients with chronic obstructive pulmonary disease: Protocol for a systematic review and meta-analysis. AU - Guo,Yu, AU - Xu,Mingmin, AU - Ji,Meiqi, AU - Zhang,Jialei, AU - Hu,Qingchuan, AU - Wei,Zeren, AU - Yan,Jian, AU - Chen,Yue, AU - Lyu,Jiaxuan, AU - Shao,Xiaoqian, AU - Wang,Ying, AU - Guo,Jiamei, AU - Wei,Yulong, PY - 2018/10/7/entrez PY - 2018/10/7/pubmed PY - 2018/10/24/medline SP - e12659 EP - e12659 JF - Medicine JO - Medicine (Baltimore) VL - 97 IS - 40 N2 - BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide with a substantial and increasing social and economic burden. Liuzijue Qigong is a kind of traditional Chinese Qigong exercises that Traditional Chinese Medicine practitioners prescribe to individuals with COPD to strengthen the internal organs' function. Liuzijue Qigong was recommended for use in COPD rehabilitation, and some clinical trials indicate that Liuzijue Qigong would produce better functional capacity and quality of life of individuals with COPD. The objective of this study is to conduct a systematic review of the existing studies to assess effectiveness and safety of Liuzijue Qigong for the prevention or treatment of COPD in patients. METHODS: We will perform the comprehensive literature search in English and Chinese electronic database. The publication period will be from inception to the search date. In addition, the clinical trial registries, dissertations, informal publication, grey literature, reference lists of studies, systematic reviews, and conference abstracts will also be collected. Two reviewers will identify relevant studies, extract data information, and then assess the methodical quality by the Cochrane risk of bias assessment tool. Only randomized controlled trials comparing Liuzijue Qigong against other intervention or nonintervention will be included. Data will be synthesized by either fixed-effect or random-effect model regarding to a heterogeneity test. The routine lung function, arterial blood gas tensions, partial pressure of carbon dioxide, functional capacity, 30 seconds sit-to-stand test, respiratory function, maximal inspiration pressure, maximal expiratory pressure, airway resistance, and specific airway conductance will be assessed as primary outcomes. The secondary outcomes involved dyspnea, and fatigue levels, respiratory muscle strength, upper and lower limb muscle strength, handgrip strength test, and health-related quality of life and safety. Meta-analysis will be performed by using Cochrane's Review Manager software (version 5.3.5). RESULTS: This systematic review and meta-analysis will provide a high-quality synthesis and evaluate the efficacy and safety based on current relevant literature evidence of Liuzijue Qigong intervention for COPD patient. CONCLUSION: Our systematic review will provide evidence to determine whether Liuzijue Qigong is an effective and safe approach to prevention and treatment of COPD patients. SN - 1536-5964 UR - https://www.unboundmedicine.com/medline/citation/30290646/Effect_of_Liuzijue_Qigong_on_patients_with_chronic_obstructive_pulmonary_disease:_Protocol_for_a_systematic_review_and_meta_analysis_ L2 - http://Insights.ovid.com/pubmed?pmid=30290646 DB - PRIME DP - Unbound Medicine ER -