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Ultracytochemical study of ouabain-sensitive, potassium-dependent p-nitrophenylphosphatase activity in the inner ear of the squirrel monkey.
Acta Otolaryngol. 1987 Mar-Apr; 103(3-4):161-9.AO

Abstract

The localization of ouabain-sensitive, K+-dependent p-nitrophenylphosphatase (K+-NPPase) activity of the Na+, K+-ATPase complex was studied ultracytochemically in the squirrel monkey inner ear. In the stria vascularis the reaction products showing K+-NPPase activity were limited to the cytoplasmic side of the plasmalemmal infoldings of the marginal cells. In the spiral prominence, a weak reaction was also found on the cytoplasmic process of the stromal cell, while no or little reaction was detected on the spiral prominence epithelium. In the dark cells of vestibular labyrinth the reaction products were observed on the basolateral interdigitation of the plasmalemma. In contrast, no reaction was observed on the apical cell surface. K+-NPPase activity was most intense in the strial marginal cell, followed by the dark cell of the ampulla and the utricle. The present results revealed that the dark cells in the vestibular labyrinth are involved in endolymph homeostasis.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

3033981

Citation

Yoshihara, T, et al. "Ultracytochemical Study of Ouabain-sensitive, Potassium-dependent P-nitrophenylphosphatase Activity in the Inner Ear of the Squirrel Monkey." Acta Oto-laryngologica, vol. 103, no. 3-4, 1987, pp. 161-9.
Yoshihara T, Usami S, Igarashi M, et al. Ultracytochemical study of ouabain-sensitive, potassium-dependent p-nitrophenylphosphatase activity in the inner ear of the squirrel monkey. Acta Otolaryngol. 1987;103(3-4):161-9.
Yoshihara, T., Usami, S., Igarashi, M., & Fermin, C. D. (1987). Ultracytochemical study of ouabain-sensitive, potassium-dependent p-nitrophenylphosphatase activity in the inner ear of the squirrel monkey. Acta Oto-laryngologica, 103(3-4), 161-9.
Yoshihara T, et al. Ultracytochemical Study of Ouabain-sensitive, Potassium-dependent P-nitrophenylphosphatase Activity in the Inner Ear of the Squirrel Monkey. Acta Otolaryngol. 1987 Mar-Apr;103(3-4):161-9. PubMed PMID: 3033981.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ultracytochemical study of ouabain-sensitive, potassium-dependent p-nitrophenylphosphatase activity in the inner ear of the squirrel monkey. AU - Yoshihara,T, AU - Usami,S, AU - Igarashi,M, AU - Fermin,C D, PY - 1987/3/1/pubmed PY - 1987/3/1/medline PY - 1987/3/1/entrez SP - 161 EP - 9 JF - Acta oto-laryngologica JO - Acta Otolaryngol VL - 103 IS - 3-4 N2 - The localization of ouabain-sensitive, K+-dependent p-nitrophenylphosphatase (K+-NPPase) activity of the Na+, K+-ATPase complex was studied ultracytochemically in the squirrel monkey inner ear. In the stria vascularis the reaction products showing K+-NPPase activity were limited to the cytoplasmic side of the plasmalemmal infoldings of the marginal cells. In the spiral prominence, a weak reaction was also found on the cytoplasmic process of the stromal cell, while no or little reaction was detected on the spiral prominence epithelium. In the dark cells of vestibular labyrinth the reaction products were observed on the basolateral interdigitation of the plasmalemma. In contrast, no reaction was observed on the apical cell surface. K+-NPPase activity was most intense in the strial marginal cell, followed by the dark cell of the ampulla and the utricle. The present results revealed that the dark cells in the vestibular labyrinth are involved in endolymph homeostasis. SN - 0001-6489 UR - https://www.unboundmedicine.com/medline/citation/3033981/Ultracytochemical_study_of_ouabain_sensitive_potassium_dependent_p_nitrophenylphosphatase_activity_in_the_inner_ear_of_the_squirrel_monkey_ DB - PRIME DP - Unbound Medicine ER -