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[The role of structural elements of ColE1-related plasmids in replication control].
Bioorg Khim. 1987 Feb; 13(2):213-7.BK

Abstract

Effect of deletions downstream from the replication origin on copy number of ColE1 related (pBR322 derived) plasmids has been studied. Along with main control elements (RNAI of defined secondary structure, the repressor protein, effectiveness of promoter upstream of gene of RNA primer) replication is influenced by transcription level propagated into the replicon region from promoters even in distal parts of plasmid. Structure of the region adjacent to the ori is important for startpoint recognition specificity, so that deletion of this region reduces the effectiveness of replication.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

rus

PubMed ID

3034293

Citation

Gurevich, A I., and N I. Babiĭ. "[The Role of Structural Elements of ColE1-related Plasmids in Replication Control]." Bioorganicheskaia Khimiia, vol. 13, no. 2, 1987, pp. 213-7.
Gurevich AI, Babiĭ NI. [The role of structural elements of ColE1-related plasmids in replication control]. Bioorg Khim. 1987;13(2):213-7.
Gurevich, A. I., & Babiĭ, N. I. (1987). [The role of structural elements of ColE1-related plasmids in replication control]. Bioorganicheskaia Khimiia, 13(2), 213-7.
Gurevich AI, Babiĭ NI. [The Role of Structural Elements of ColE1-related Plasmids in Replication Control]. Bioorg Khim. 1987;13(2):213-7. PubMed PMID: 3034293.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The role of structural elements of ColE1-related plasmids in replication control]. AU - Gurevich,A I, AU - Babiĭ,N I, PY - 1987/2/1/pubmed PY - 1987/2/1/medline PY - 1987/2/1/entrez SP - 213 EP - 7 JF - Bioorganicheskaia khimiia JO - Bioorg. Khim. VL - 13 IS - 2 N2 - Effect of deletions downstream from the replication origin on copy number of ColE1 related (pBR322 derived) plasmids has been studied. Along with main control elements (RNAI of defined secondary structure, the repressor protein, effectiveness of promoter upstream of gene of RNA primer) replication is influenced by transcription level propagated into the replicon region from promoters even in distal parts of plasmid. Structure of the region adjacent to the ori is important for startpoint recognition specificity, so that deletion of this region reduces the effectiveness of replication. SN - 0132-3423 UR - https://www.unboundmedicine.com/medline/citation/3034293/[The_role_of_structural_elements_of_ColE1_related_plasmids_in_replication_control]_ DB - PRIME DP - Unbound Medicine ER -