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Intraoral manifestation of systemic AL amyloidosis with unique microscopic presentation of intracellular amyloid deposition in striated muscles.
Pol J Pathol. 2018; 69(2):200-204.PJ

Abstract

We report the history of a 59-year old patient with systemic AL amyloidosis of intraoral manifestation. The patient first presented with complaints about dysphagia and remarkable enlargement of the tongue with highly reduced mobility, as well as bilateral submucosal thickenings on the cheeks. Histopathological examination of the incisional biopsy of the buccal mucosa and underlying tissues revealed AL amyloidosis. The microscopic presentation was, however, unique, as the amyloid deposits were present intracellularly in the striated muscles. The subsequent bone marrow biopsy confirmed the diagnosis of primary amyloidosis/multiple myeloma - associated amyloidosis.

Authors

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Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

30351869

Citation

Oruba, Zuzanna, et al. "Intraoral Manifestation of Systemic AL Amyloidosis With Unique Microscopic Presentation of Intracellular Amyloid Deposition in Striated Muscles." Polish Journal of Pathology : Official Journal of the Polish Society of Pathologists, vol. 69, no. 2, 2018, pp. 200-204.
Oruba Z, Kaczmarzyk T, Urbańczyk K, et al. Intraoral manifestation of systemic AL amyloidosis with unique microscopic presentation of intracellular amyloid deposition in striated muscles. Pol J Pathol. 2018;69(2):200-204.
Oruba, Z., Kaczmarzyk, T., Urbańczyk, K., Jurczyszyn, A., Fornagiel, S., Gałązka, K., Bednarczyk, A., & Chomyszyn-Gajewska, M. (2018). Intraoral manifestation of systemic AL amyloidosis with unique microscopic presentation of intracellular amyloid deposition in striated muscles. Polish Journal of Pathology : Official Journal of the Polish Society of Pathologists, 69(2), 200-204. https://doi.org/10.5114/pjp.2018.76705
Oruba Z, et al. Intraoral Manifestation of Systemic AL Amyloidosis With Unique Microscopic Presentation of Intracellular Amyloid Deposition in Striated Muscles. Pol J Pathol. 2018;69(2):200-204. PubMed PMID: 30351869.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intraoral manifestation of systemic AL amyloidosis with unique microscopic presentation of intracellular amyloid deposition in striated muscles. AU - Oruba,Zuzanna, AU - Kaczmarzyk,Tomasz, AU - Urbańczyk,Katarzyna, AU - Jurczyszyn,Artur, AU - Fornagiel,Szymon, AU - Gałązka,Krystyna, AU - Bednarczyk,Anna, AU - Chomyszyn-Gajewska,Maria, PY - 2018/10/24/entrez PY - 2018/10/24/pubmed PY - 2019/5/21/medline KW - amyloid KW - macroglossia KW - multiple myeloma KW - oral manifestation KW - AL amyloidosis SP - 200 EP - 204 JF - Polish journal of pathology : official journal of the Polish Society of Pathologists JO - Pol J Pathol VL - 69 IS - 2 N2 - We report the history of a 59-year old patient with systemic AL amyloidosis of intraoral manifestation. The patient first presented with complaints about dysphagia and remarkable enlargement of the tongue with highly reduced mobility, as well as bilateral submucosal thickenings on the cheeks. Histopathological examination of the incisional biopsy of the buccal mucosa and underlying tissues revealed AL amyloidosis. The microscopic presentation was, however, unique, as the amyloid deposits were present intracellularly in the striated muscles. The subsequent bone marrow biopsy confirmed the diagnosis of primary amyloidosis/multiple myeloma - associated amyloidosis. SN - 1233-9687 UR - https://www.unboundmedicine.com/medline/citation/30351869/Intraoral_manifestation_of_systemic_AL_amyloidosis_with_unique_microscopic_presentation_of_intracellular_amyloid_deposition_in_striated_muscles_ L2 - http://www.pjp.termedia.pl/showarticle.php?id=33190 DB - PRIME DP - Unbound Medicine ER -