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A review of the monkeypox virus and a recent outbreak of skin rash disease in Nigeria.
J Med Virol. 2019 04; 91(4):533-540.JM

Abstract

Since the eradication of smallpox approximately 39 years ago, monkeypox virus remains the most pathogenic poxvirus, being mainly restricted to Central and West Africa. Before 1970, there were no reports of human monkeypox in Nigeria, while between 1971 and 1978 there were three cases, with none having been reported thereafter. However, in September 2017, a case of contagious skin rash disease, typical of monkeypox, was observed in an 11-year-old boy from the southern part of the country and confirmed to be associated with the monkeypox virus. This large outbreak consisted of 262 suspected, 115 confirmed cases, and 7 mortalities across 26 states and the Federal Capital Territory (FCT), Abuja. The aim of this manuscript is to provide an updated, comprehensive, and timely review of monkeypox, an important emerging infection in Nigeria. Monkeypox is now a major threat to global health security, requiring an urgent multidisciplinary approach involving veterinarians, physicians, virologists, and public health experts to fast-track the development of diagnostic assays, vaccines, antivirals, and other control strategies.

Authors+Show Affiliations

Department of Medical Microbiology and Parasitology, College of Health Sciences, Faculty of Clinical Sciences, Bayero University, Kano, Nigeria.Virology, Microbiology and Infectious Diseases Research Group, School of Health Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

30357851

Citation

Kabuga, Auwal I., and Mohamed E. El Zowalaty. "A Review of the Monkeypox Virus and a Recent Outbreak of Skin Rash Disease in Nigeria." Journal of Medical Virology, vol. 91, no. 4, 2019, pp. 533-540.
Kabuga AI, El Zowalaty ME. A review of the monkeypox virus and a recent outbreak of skin rash disease in Nigeria. J Med Virol. 2019;91(4):533-540.
Kabuga, A. I., & El Zowalaty, M. E. (2019). A review of the monkeypox virus and a recent outbreak of skin rash disease in Nigeria. Journal of Medical Virology, 91(4), 533-540. https://doi.org/10.1002/jmv.25348
Kabuga AI, El Zowalaty ME. A Review of the Monkeypox Virus and a Recent Outbreak of Skin Rash Disease in Nigeria. J Med Virol. 2019;91(4):533-540. PubMed PMID: 30357851.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A review of the monkeypox virus and a recent outbreak of skin rash disease in Nigeria. AU - Kabuga,Auwal I, AU - El Zowalaty,Mohamed E, Y1 - 2018/11/19/ PY - 2018/07/25/received PY - 2018/10/17/accepted PY - 2018/10/26/pubmed PY - 2020/3/18/medline PY - 2018/10/26/entrez KW - Africa KW - Nigeria KW - antipoxvirus agents KW - epidemiology KW - infectious diseases KW - monkeypox KW - outbreak KW - poxviruses KW - re-emerging infection KW - zoonotic SP - 533 EP - 540 JF - Journal of medical virology JO - J Med Virol VL - 91 IS - 4 N2 - Since the eradication of smallpox approximately 39 years ago, monkeypox virus remains the most pathogenic poxvirus, being mainly restricted to Central and West Africa. Before 1970, there were no reports of human monkeypox in Nigeria, while between 1971 and 1978 there were three cases, with none having been reported thereafter. However, in September 2017, a case of contagious skin rash disease, typical of monkeypox, was observed in an 11-year-old boy from the southern part of the country and confirmed to be associated with the monkeypox virus. This large outbreak consisted of 262 suspected, 115 confirmed cases, and 7 mortalities across 26 states and the Federal Capital Territory (FCT), Abuja. The aim of this manuscript is to provide an updated, comprehensive, and timely review of monkeypox, an important emerging infection in Nigeria. Monkeypox is now a major threat to global health security, requiring an urgent multidisciplinary approach involving veterinarians, physicians, virologists, and public health experts to fast-track the development of diagnostic assays, vaccines, antivirals, and other control strategies. SN - 1096-9071 UR - https://www.unboundmedicine.com/medline/citation/30357851/A_review_of_the_monkeypox_virus_and_a_recent_outbreak_of_skin_rash_disease_in_Nigeria_ L2 - https://doi.org/10.1002/jmv.25348 DB - PRIME DP - Unbound Medicine ER -