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Protease inhibitory, insecticidal and deterrent effects of the trypsin-inhibitor benzamidine on the velvetbean caterpillar in soybean.
An Acad Bras Cienc. 2018 Oct-Dec; 90(4):3475-3482.AA

Abstract

The recognition of protease inhibitors with insecticidal activity is important as a basis for the development of mimetic peptides with potential use as biorational insecticides. We sprayed benzamidine on soybean plants and assessed whether this potent synthetic trypsin-inhibitor has protease inhibitory, insecticidal and deterrent effects on the velvetbean caterpillar Anticarsia gemmatalis Hübner (Lepidoptera: Erebidae). Activity of trypsin inhibition in soybean leaves was increased and total proteolytic activity in the midgut extract from larvae fed on these leaves was reduced by benzamidine. Different concentrations of benzamidine sprayed on the plant caused approximately 50 % of larval mortality, and larval choice and moth preference and oviposition were all negatively affected. Low concentrations of benzamidine increased mortality and hindered insect choice and oviposition as well as higher doses. Since many synthetic protease inhibitors are usually expensive, small doses of benzamidine may be effective to protect soybean against A. gemmatalis attack. Our results highlight the potential of synthetic protease inhibitors for insecticidal and deterrent purposes in insect pest management.

Authors+Show Affiliations

Instituto Capixaba de Pesquisa, Assistência Técnica e Extensão Rural, Rua Raimundo Pereira, 18A, 29615-000, Laranja da Terra, ES, Brazil.Departamento de Engenharia de Biossistemas, Universidade Federal de São João del Rei, Campus Dom Bosco, 36301-160, São João del Rei, MG, Brazil.Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, Avenida Peter Henry Rolfs, s/n, 36570‑000, Viçosa, MG, Brazil.Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, Avenida Peter Henry Rolfs, s/n, 36570‑000, Viçosa, MG, Brazil.Instituto de Ciências Agrárias, Universidade Federal de Viçosa, Campus Rio Paranaíba, 38810-000, Rio Paranaíba, MG, Brazil.Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, Avenida Peter Henry Rolfs, s/n, 36570‑000, Viçosa, MG, Brazil.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30365718

Citation

Pilon, Anderson M., et al. "Protease Inhibitory, Insecticidal and Deterrent Effects of the Trypsin-inhibitor Benzamidine On the Velvetbean Caterpillar in Soybean." Anais Da Academia Brasileira De Ciencias, vol. 90, no. 4, 2018, pp. 3475-3482.
Pilon AM, Campos WG, Silva CR, et al. Protease inhibitory, insecticidal and deterrent effects of the trypsin-inhibitor benzamidine on the velvetbean caterpillar in soybean. An Acad Bras Cienc. 2018;90(4):3475-3482.
Pilon, A. M., Campos, W. G., Silva, C. R., Cordeiro, G., Silva, C. R., & Oliveira, M. G. A. (2018). Protease inhibitory, insecticidal and deterrent effects of the trypsin-inhibitor benzamidine on the velvetbean caterpillar in soybean. Anais Da Academia Brasileira De Ciencias, 90(4), 3475-3482. https://doi.org/10.1590/0001-3765201820180159
Pilon AM, et al. Protease Inhibitory, Insecticidal and Deterrent Effects of the Trypsin-inhibitor Benzamidine On the Velvetbean Caterpillar in Soybean. An Acad Bras Cienc. 2018 Oct-Dec;90(4):3475-3482. PubMed PMID: 30365718.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Protease inhibitory, insecticidal and deterrent effects of the trypsin-inhibitor benzamidine on the velvetbean caterpillar in soybean. AU - Pilon,Anderson M, AU - Campos,Wellington G, AU - Silva,Carolina R, AU - Cordeiro,Glaúcia, AU - Silva,Camila R, AU - Oliveira,Maria Goreti A, Y1 - 2018/10/18/ PY - 2018/02/16/received PY - 2018/03/15/accepted PY - 2018/10/27/pubmed PY - 2019/2/7/medline PY - 2018/10/27/entrez SP - 3475 EP - 3482 JF - Anais da Academia Brasileira de Ciencias JO - An Acad Bras Cienc VL - 90 IS - 4 N2 - The recognition of protease inhibitors with insecticidal activity is important as a basis for the development of mimetic peptides with potential use as biorational insecticides. We sprayed benzamidine on soybean plants and assessed whether this potent synthetic trypsin-inhibitor has protease inhibitory, insecticidal and deterrent effects on the velvetbean caterpillar Anticarsia gemmatalis Hübner (Lepidoptera: Erebidae). Activity of trypsin inhibition in soybean leaves was increased and total proteolytic activity in the midgut extract from larvae fed on these leaves was reduced by benzamidine. Different concentrations of benzamidine sprayed on the plant caused approximately 50 % of larval mortality, and larval choice and moth preference and oviposition were all negatively affected. Low concentrations of benzamidine increased mortality and hindered insect choice and oviposition as well as higher doses. Since many synthetic protease inhibitors are usually expensive, small doses of benzamidine may be effective to protect soybean against A. gemmatalis attack. Our results highlight the potential of synthetic protease inhibitors for insecticidal and deterrent purposes in insect pest management. SN - 1678-2690 UR - https://www.unboundmedicine.com/medline/citation/30365718/Protease_inhibitory_insecticidal_and_deterrent_effects_of_the_trypsin_inhibitor_benzamidine_on_the_velvetbean_caterpillar_in_soybean_ DB - PRIME DP - Unbound Medicine ER -