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Neuroborreliosis.
Neurol Clin. 2018 11; 36(4):821-830.NC

Abstract

Neurologic manifestations of nervous system infection with Borrelia burgdorferi, Borrelia garinii, and Borrelia afzelii are qualitatively similar, and include lymphocytic meningitis, cranial neuritis, radiculoneuritis, and other focal or multifocal mononeuropathies. Parenchymal central nervous system (CNS) infection occurs rarely. Neurobehavioral changes are common, but are rarely evidence of CNS infection. Diagnosis requires likely exposure and a finding with high diagnostic positive predictive value, specifically erythema migrans, or laboratory support, typically positive 2-tiered serologic testing. CNS infection is often evidenced by a cerebrospinal fluid pleocytosis and intrathecal production of specific antibody.

Authors+Show Affiliations

Department of Neurosciences, Overlook Medical Center, 99 Beauvoir Avenue, Summit, NJ 07902, USA; Sidney Kimmel Medical College, Thomas Jefferson University, 1025 Walnut Street, Philadelphia, PA 19107, USA. Electronic address: John.halperin@atlantichealth.org.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

30366557

Citation

Halperin, John J.. "Neuroborreliosis." Neurologic Clinics, vol. 36, no. 4, 2018, pp. 821-830.
Halperin JJ. Neuroborreliosis. Neurol Clin. 2018;36(4):821-830.
Halperin, J. J. (2018). Neuroborreliosis. Neurologic Clinics, 36(4), 821-830. https://doi.org/10.1016/j.ncl.2018.06.006
Halperin JJ. Neuroborreliosis. Neurol Clin. 2018;36(4):821-830. PubMed PMID: 30366557.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Neuroborreliosis. A1 - Halperin,John J, PY - 2018/10/28/entrez PY - 2018/10/28/pubmed PY - 2019/8/29/medline KW - Borrelia burgdorferi KW - Borreliella KW - Diagnosis KW - Lyme KW - Mononeuropathy multiplex KW - Neuroborreliosis KW - Radiculoneuritis KW - Treatment SP - 821 EP - 830 JF - Neurologic clinics JO - Neurol Clin VL - 36 IS - 4 N2 - Neurologic manifestations of nervous system infection with Borrelia burgdorferi, Borrelia garinii, and Borrelia afzelii are qualitatively similar, and include lymphocytic meningitis, cranial neuritis, radiculoneuritis, and other focal or multifocal mononeuropathies. Parenchymal central nervous system (CNS) infection occurs rarely. Neurobehavioral changes are common, but are rarely evidence of CNS infection. Diagnosis requires likely exposure and a finding with high diagnostic positive predictive value, specifically erythema migrans, or laboratory support, typically positive 2-tiered serologic testing. CNS infection is often evidenced by a cerebrospinal fluid pleocytosis and intrathecal production of specific antibody. SN - 1557-9875 UR - https://www.unboundmedicine.com/medline/citation/30366557/Neuroborreliosis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0733-8619(18)31240-4 DB - PRIME DP - Unbound Medicine ER -
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