Tags

Type your tag names separated by a space and hit enter

Dengue vaccine: WHO position paper, September 2018 - Recommendations.
Vaccine. 2019 08 14; 37(35):4848-4849.V

Abstract

This article presents the World Health Organization's (WHO) recommendations on the use of dengue vaccine excerpted from the WHO position paper on dengue vaccine - September 2018, published in the Weekly Epidemiological Record [1]. This position paper replaces the July 2016 WHO position paper concerning the first licensed dengue vaccine, CYD-TDV [2]. The position paper presents new evidence that became available in November 2017. A retrospective analysis of data from clinical trials, using a new serological assay classified trial participants according to their dengue serostatus prior to receipt of the first vaccine dose. The analysis revealed an excess risk of severe dengue in seronegative vaccine recipients compared to seronegative non-vaccinated individuals, while confirming long-term protection in seropositive individuals [3]. The paper provides revised guidance on dengue vaccination strategies from a population health perspective. Footnotes to this paper provide a number of core references including references to grading tables that assess the quality of the scientific evidence, and to the evidence-to-recommendation table. In accordance with its mandate to provide guidance to Member States on health policy matters, WHO issues a series of regularly updated position papers on vaccines and combinations of vaccines against diseases that have an international public health impact. These papers are concerned primarily with the use of vaccines in large-scale immunization programmes; they summarize essential background information on diseases and vaccines, and conclude with WHO's current position on the use of vaccines in the global context. Recommendations on the use of dengue vaccine CYD-TDV were discussed by SAGE in April 2018; evidence presented at the meeting can be accessed at: http://www.who.int/immunization/sage/meetings/2018/april/presentations_background_docs/en/.

Pub Type(s)

Historical Article
Journal Article

Language

eng

PubMed ID

30424888

Citation

"Dengue Vaccine: WHO Position Paper, September 2018 - Recommendations." Vaccine, vol. 37, no. 35, 2019, pp. 4848-4849.
Dengue vaccine: WHO position paper, September 2018 - Recommendations. Vaccine. 2019;37(35):4848-4849.
(2019). Dengue vaccine: WHO position paper, September 2018 - Recommendations. Vaccine, 37(35), 4848-4849. https://doi.org/10.1016/j.vaccine.2018.09.063
Dengue Vaccine: WHO Position Paper, September 2018 - Recommendations. Vaccine. 2019 08 14;37(35):4848-4849. PubMed PMID: 30424888.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dengue vaccine: WHO position paper, September 2018 - Recommendations. Y1 - 2018/11/10/ PY - 2018/09/19/received PY - 2018/09/26/accepted PY - 2018/11/15/pubmed PY - 2020/5/7/medline PY - 2018/11/15/entrez KW - Dengue vaccine KW - Vaccine position paper KW - WHO position paper SP - 4848 EP - 4849 JF - Vaccine JO - Vaccine VL - 37 IS - 35 N2 - This article presents the World Health Organization's (WHO) recommendations on the use of dengue vaccine excerpted from the WHO position paper on dengue vaccine - September 2018, published in the Weekly Epidemiological Record [1]. This position paper replaces the July 2016 WHO position paper concerning the first licensed dengue vaccine, CYD-TDV [2]. The position paper presents new evidence that became available in November 2017. A retrospective analysis of data from clinical trials, using a new serological assay classified trial participants according to their dengue serostatus prior to receipt of the first vaccine dose. The analysis revealed an excess risk of severe dengue in seronegative vaccine recipients compared to seronegative non-vaccinated individuals, while confirming long-term protection in seropositive individuals [3]. The paper provides revised guidance on dengue vaccination strategies from a population health perspective. Footnotes to this paper provide a number of core references including references to grading tables that assess the quality of the scientific evidence, and to the evidence-to-recommendation table. In accordance with its mandate to provide guidance to Member States on health policy matters, WHO issues a series of regularly updated position papers on vaccines and combinations of vaccines against diseases that have an international public health impact. These papers are concerned primarily with the use of vaccines in large-scale immunization programmes; they summarize essential background information on diseases and vaccines, and conclude with WHO's current position on the use of vaccines in the global context. Recommendations on the use of dengue vaccine CYD-TDV were discussed by SAGE in April 2018; evidence presented at the meeting can be accessed at: http://www.who.int/immunization/sage/meetings/2018/april/presentations_background_docs/en/. SN - 1873-2518 UR - https://www.unboundmedicine.com/medline/citation/30424888/Dengue_vaccine:_WHO_position_paper_September_2018___Recommendations_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0264-410X(18)31339-2 DB - PRIME DP - Unbound Medicine ER -