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[Analysis of treatment with 167 critically ill pregnant women in intensive care unit].
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2018 Oct; 30(10):964-967.ZW

Abstract

OBJECTIVE

To analyze the pathogenic factors, clinical features and treatment measures of critically ill pregnant women so as to provide experience for improving the success rate of treatment.

METHODS

The clinical data of 167 cases of critically ill pregnant women who admitted to intensive care unit (ICU) of the Affiliated Hospital of Guizhou Medical University from January 2013 to December 2017 were collected, and the disease distribution of patients, the causes of postpartum hemorrhage, the treatment situation and the results. Patients were divided into obstetrical complications group, pregnancy complicated with basic diseases group and other complicated diseases group according to disease types, and the treatment status of each group was analyzed.

RESULTS

Among 167 critically ill pregnant women, 118 cases (70.6%) were in the obstetric complications group, 26 cases (15.6%) were in the pregnancy complicated with basic diseases group, and 23 cases (13.8%) were in the other complicated diseases group. Nine cases died in 167 critically ill pregnant women, with a mortality rate of 5.4%. Postpartum hemorrhage was the major obstetric complication (35.3%), and the coagulation function of 59 patients with postpartum hemorrhage was significantly improved 48 hours after active hemostasis and reasonable blood transfusion [compared to entering the ICU, prothrombin time (PT, s): 14.49±4.66 vs. 23.39±8.11, activated partial thromboplastin time (APTT, s): 52.94±36.36 vs. 87.35±74.69, fibrinogen (Fib, g/L): 2.91±1.03 vs. 1.03±0.65, platelet count (PLT, ×109/L): 94.85±30.09 vs. 43.15±24.07, all P < 0.01]. Compared with pregnancy complicated basic diseases group and other complicated diseases group, the acute physiology and chronic health evaluation II (APACHE II) scores was reduced significantly in obstetrical complications group (10.41±4.85 vs. 16.46±13.87, 16.90±8.82, both P < 0.05), the length of ICU stay was significantly reduced (hours: 57.83±34.67 vs. 79.64±36.01, 278.30±83.72, both P < 0.05). Compared with other complicated diseases group, the mechanical ventilation time [hours :14 (6, 38) vs. 43 (12, 396)] and mortality (0.8% vs. 13.0%) were significantly decreased in obstetrical complications group (both P < 0.05).

CONCLUSIONS

Observe the changes of the condition closely, necessary hemodynamic treatment, respiratory support, and organ function support with critically ill pregnant women can improve the rescue success rate and prognosis.

Authors+Show Affiliations

Department of Critical Care Medicine, the Affiliated Hospital of Guizhou Medical University, Guiyang 550004, Guizhou, China. Corresponding author: Wang Difen, Email: 1078666485@qq.com.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

chi

PubMed ID

30439318

Citation

Liu, Ying, et al. "[Analysis of Treatment With 167 Critically Ill Pregnant Women in Intensive Care Unit]." Zhonghua Wei Zhong Bing Ji Jiu Yi Xue, vol. 30, no. 10, 2018, pp. 964-967.
Liu Y, Wang D, Wang Y, et al. [Analysis of treatment with 167 critically ill pregnant women in intensive care unit]. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2018;30(10):964-967.
Liu, Y., Wang, D., Wang, Y., Fu, J., & Tan, W. (2018). [Analysis of treatment with 167 critically ill pregnant women in intensive care unit]. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue, 30(10), 964-967. https://doi.org/10.3760/cma.j.issn.2095-4352.2018.010.012
Liu Y, et al. [Analysis of Treatment With 167 Critically Ill Pregnant Women in Intensive Care Unit]. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2018;30(10):964-967. PubMed PMID: 30439318.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Analysis of treatment with 167 critically ill pregnant women in intensive care unit]. AU - Liu,Ying, AU - Wang,Difen, AU - Wang,Ying, AU - Fu,Jiangquan, AU - Tan,Wanlin, PY - 2018/11/16/entrez PY - 2018/11/16/pubmed PY - 2019/3/13/medline SP - 964 EP - 967 JF - Zhonghua wei zhong bing ji jiu yi xue JO - Zhonghua Wei Zhong Bing Ji Jiu Yi Xue VL - 30 IS - 10 N2 - OBJECTIVE: To analyze the pathogenic factors, clinical features and treatment measures of critically ill pregnant women so as to provide experience for improving the success rate of treatment. METHODS: The clinical data of 167 cases of critically ill pregnant women who admitted to intensive care unit (ICU) of the Affiliated Hospital of Guizhou Medical University from January 2013 to December 2017 were collected, and the disease distribution of patients, the causes of postpartum hemorrhage, the treatment situation and the results. Patients were divided into obstetrical complications group, pregnancy complicated with basic diseases group and other complicated diseases group according to disease types, and the treatment status of each group was analyzed. RESULTS: Among 167 critically ill pregnant women, 118 cases (70.6%) were in the obstetric complications group, 26 cases (15.6%) were in the pregnancy complicated with basic diseases group, and 23 cases (13.8%) were in the other complicated diseases group. Nine cases died in 167 critically ill pregnant women, with a mortality rate of 5.4%. Postpartum hemorrhage was the major obstetric complication (35.3%), and the coagulation function of 59 patients with postpartum hemorrhage was significantly improved 48 hours after active hemostasis and reasonable blood transfusion [compared to entering the ICU, prothrombin time (PT, s): 14.49±4.66 vs. 23.39±8.11, activated partial thromboplastin time (APTT, s): 52.94±36.36 vs. 87.35±74.69, fibrinogen (Fib, g/L): 2.91±1.03 vs. 1.03±0.65, platelet count (PLT, ×109/L): 94.85±30.09 vs. 43.15±24.07, all P < 0.01]. Compared with pregnancy complicated basic diseases group and other complicated diseases group, the acute physiology and chronic health evaluation II (APACHE II) scores was reduced significantly in obstetrical complications group (10.41±4.85 vs. 16.46±13.87, 16.90±8.82, both P < 0.05), the length of ICU stay was significantly reduced (hours: 57.83±34.67 vs. 79.64±36.01, 278.30±83.72, both P < 0.05). Compared with other complicated diseases group, the mechanical ventilation time [hours :14 (6, 38) vs. 43 (12, 396)] and mortality (0.8% vs. 13.0%) were significantly decreased in obstetrical complications group (both P < 0.05). CONCLUSIONS: Observe the changes of the condition closely, necessary hemodynamic treatment, respiratory support, and organ function support with critically ill pregnant women can improve the rescue success rate and prognosis. SN - 2095-4352 UR - https://www.unboundmedicine.com/medline/citation/30439318/[Analysis_of_treatment_with_167_critically_ill_pregnant_women_in_intensive_care_unit]_ DB - PRIME DP - Unbound Medicine ER -