Tags

Type your tag names separated by a space and hit enter

Aquatic ecotoxicity of an antidepressant, sertraline hydrochloride, on microbial communities.
Sci Total Environ. 2019 Mar 01; 654:129-134.ST

Abstract

Sertraline hydrochloride (Ser-HCl), a widely used antidepressant, becomes an aquatic contaminant via metabolic excretion and improper disposal; however, it is unknown how Ser-HCl affects aquatic microbial communities. The present study investigated the effects of Ser on the structures of aquatic microbial communities via high-throughput sequencing analyses. Ser-HCl treatment inhibited the growth of two model algae (the green alga, Chlorella vulgaris, and the cyanobacterium, Microcystis aeruginosa) and decreased the chlorophyll a (Chl-a) concentration in the microcosm to reduce the photosynthetic efficiency. High-throughput sequencing analyses showed that exposure to Ser-HCl disturbed the balance of cyanobacteria species by stimulating the growth of specific cyanobacteria. Among eukaryotes, the richness as well as the diversity indices were significantly enhanced after 5 days of Ser-HCl treatment but sharply decreased with exposure time. Nucleariida occupied an absolute majority (97.83%) within the eukaryotes, implicating that Ser-HCl disturbed the ecological equilibrium in microcosms. Ser-HCl will continue to be an environmental contaminant due to its wide usage and production. Our current study clarified the potential ecological risk of Ser-HCl to aquatic microorganisms. These findings suggest that more attention should be given to the negative effects of these bioactive pollutants on aquatic environments.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China.

College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China.

College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China.

College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China.

College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China.

College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China.

Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China. Electronic address: hfqian@zjut.edu.cn.

MeSH

Antidepressive AgentsChlorella vulgarisChlorophyllEcotoxicologyHigh-Throughput Nucleotide SequencingMicrobiotaMicrocystisPhotosynthesisRNA, Ribosomal, 16SSertralineWater Pollutants, Chemical

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30439689

Citation

Yang, Zhaopeng, et al. "Aquatic Ecotoxicity of an Antidepressant, Sertraline Hydrochloride, On Microbial Communities." The Science of the Total Environment, vol. 654, 2019, pp. 129-134.

Yang Z, Lu T, Zhu Y, et al. Aquatic ecotoxicity of an antidepressant, sertraline hydrochloride, on microbial communities. Sci Total Environ. 2019;654:129-134.

Yang, Z., Lu, T., Zhu, Y., Zhang, Q., Zhou, Z., Pan, X., & Qian, H. (2019). Aquatic ecotoxicity of an antidepressant, sertraline hydrochloride, on microbial communities. The Science of the Total Environment, 654, 129-134. https://doi.org/10.1016/j.scitotenv.2018.11.164

Yang Z, et al. Aquatic Ecotoxicity of an Antidepressant, Sertraline Hydrochloride, On Microbial Communities. Sci Total Environ. 2019 Mar 1;654:129-134. PubMed PMID: 30439689.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Aquatic ecotoxicity of an antidepressant, sertraline hydrochloride, on microbial communities. AU - Yang,Zhaopeng, AU - Lu,Tao, AU - Zhu,Youchao, AU - Zhang,Qi, AU - Zhou,Zhigao, AU - Pan,Xiangliang, AU - Qian,Haifeng, Y1 - 2018/11/12/ PY - 2018/09/25/received PY - 2018/11/07/revised PY - 2018/11/10/accepted PY - 2018/11/16/pubmed PY - 2019/3/19/medline PY - 2018/11/16/entrez KW - Antidepressants KW - Cyanobacteria KW - Ecotoxicity KW - Microbial community KW - Sertraline hydrochloride SP - 129 EP - 134 JF - The Science of the total environment JO - Sci Total Environ VL - 654 N2 - Sertraline hydrochloride (Ser-HCl), a widely used antidepressant, becomes an aquatic contaminant via metabolic excretion and improper disposal; however, it is unknown how Ser-HCl affects aquatic microbial communities. The present study investigated the effects of Ser on the structures of aquatic microbial communities via high-throughput sequencing analyses. Ser-HCl treatment inhibited the growth of two model algae (the green alga, Chlorella vulgaris, and the cyanobacterium, Microcystis aeruginosa) and decreased the chlorophyll a (Chl-a) concentration in the microcosm to reduce the photosynthetic efficiency. High-throughput sequencing analyses showed that exposure to Ser-HCl disturbed the balance of cyanobacteria species by stimulating the growth of specific cyanobacteria. Among eukaryotes, the richness as well as the diversity indices were significantly enhanced after 5 days of Ser-HCl treatment but sharply decreased with exposure time. Nucleariida occupied an absolute majority (97.83%) within the eukaryotes, implicating that Ser-HCl disturbed the ecological equilibrium in microcosms. Ser-HCl will continue to be an environmental contaminant due to its wide usage and production. Our current study clarified the potential ecological risk of Ser-HCl to aquatic microorganisms. These findings suggest that more attention should be given to the negative effects of these bioactive pollutants on aquatic environments. SN - 1879-1026 UR - https://www.unboundmedicine.com/medline/citation/30439689/Aquatic_ecotoxicity_of_an_antidepressant_sertraline_hydrochloride_on_microbial_communities_ DB - PRIME DP - Unbound Medicine ER -