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Armadillo IgG and IgM antibody responses to phenolic glycolipid-I during experimental infection with M. leprae.
Int J Lepr Other Mycobact Dis. 1988 Sep; 56(3):422-7.IJ

Abstract

The kinetics of antibody responses of Mycobacterium leprae-infected armadillos to phenolic glycolipid-I (PGL-I) were studied by means of ELISA. The levels of both IgG and IgM antibodies to PGL-I increased with time. Some animals were less susceptible to disseminations of M. leprae infection and lived longer than others. These animals had high absorbance values (greater than 0.7) for IgG anti-PGL-I compared to more susceptible armadillos that had lower absorbance values for IgG anti-PGL-I.

Authors+Show Affiliations

Vadiee AR
Laboratory Research Branch, GWL Hansen's Disease Center, Carville, Louisiana 70721.
Shannon EJ
No affiliation info available
Gillis TP
No affiliation info available
Mshana RN
No affiliation info available
Hastings RC
No affiliation info available

MeSH

AnimalsAntibodies, BacterialAntigens, BacterialArmadillosEnzyme-Linked Immunosorbent AssayGlycolipidsImmunoglobulin GImmunoglobulin MKineticsLeprosyMycobacterium leprae

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3047283

Citation

Vadiee, A R., et al. "Armadillo IgG and IgM Antibody Responses to Phenolic glycolipid-I During Experimental Infection With M. Leprae." International Journal of Leprosy and Other Mycobacterial Diseases : Official Organ of the International Leprosy Association, vol. 56, no. 3, 1988, pp. 422-7.
Vadiee AR, Shannon EJ, Gillis TP, et al. Armadillo IgG and IgM antibody responses to phenolic glycolipid-I during experimental infection with M. leprae. Int J Lepr Other Mycobact Dis. 1988;56(3):422-7.
Vadiee, A. R., Shannon, E. J., Gillis, T. P., Mshana, R. N., & Hastings, R. C. (1988). Armadillo IgG and IgM antibody responses to phenolic glycolipid-I during experimental infection with M. leprae. International Journal of Leprosy and Other Mycobacterial Diseases : Official Organ of the International Leprosy Association, 56(3), 422-7.
Vadiee AR, et al. Armadillo IgG and IgM Antibody Responses to Phenolic glycolipid-I During Experimental Infection With M. Leprae. Int J Lepr Other Mycobact Dis. 1988;56(3):422-7. PubMed PMID: 3047283.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Armadillo IgG and IgM antibody responses to phenolic glycolipid-I during experimental infection with M. leprae. AU - Vadiee,A R, AU - Shannon,E J, AU - Gillis,T P, AU - Mshana,R N, AU - Hastings,R C, PY - 1988/9/1/pubmed PY - 1988/9/1/medline PY - 1988/9/1/entrez SP - 422 EP - 7 JF - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association JO - Int J Lepr Other Mycobact Dis VL - 56 IS - 3 N2 - The kinetics of antibody responses of Mycobacterium leprae-infected armadillos to phenolic glycolipid-I (PGL-I) were studied by means of ELISA. The levels of both IgG and IgM antibodies to PGL-I increased with time. Some animals were less susceptible to disseminations of M. leprae infection and lived longer than others. These animals had high absorbance values (greater than 0.7) for IgG anti-PGL-I compared to more susceptible armadillos that had lower absorbance values for IgG anti-PGL-I. SN - 0148-916X UR - https://www.unboundmedicine.com/medline/citation/3047283/Armadillo_IgG_and_IgM_antibody_responses_to_phenolic_glycolipid_I_during_experimental_infection_with_M__leprae_ DB - PRIME DP - Unbound Medicine ER -