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Report: Wound healing activity of Hymenocallis littoralis - Moving beyond ornamental plant.
Pak J Pharm Sci. 2018 Nov; 31(6):2537-2543.PJ

Abstract

Spider lily (Hymenocallis littoralis) belongs to Amaryllidaceae family is a well-known plant species for its medicinal properties. The inhibitory effects of H. littoralis methanol sonication extracts were evaluated for wound healing activity. This is the first report on the wound healing activity of Malaysian origin H. littoralis. The bulb, flower, root, anther, stem and leaves of H. littoralis methanol sonication extracts were used for scratch-wound assay. The cell line was treated with two different concentrations; 1 and 10μg/ml of extracts. The extracts were prepared freshly by dissolving in sterile phosphate saline buffer (PBS) and the healing activity was observed from 2, 4, 8, 12, 24, 36 and 48 h. The bulb, root, stem and anther methanol extracts demonstrated active wound healing activities at 1 μg mL-1at 36 h of treatment. At the low concentration the bulb, root, stem and anther methanol extracts heals the wound compared to leaf and flower extracts. It's demonstrated that these extracts contain effective phytochemical substances which are responsible for wound healing process. This finding suggests the potential application of H. littoralis methanol extract in wound healing activity.

Authors+Show Affiliations

School of Biological Sciences, Universiti Sains Malaysia, Minden, Penang, Malaysia.Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Minden, Penang, Malaysia.School of Pharmaceutical Sciences Universiti Sains Malaysia, Minden, Penang, Malaysia.Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Minden, Penang, Malaysia.Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Minden, Penang, Malaysia.School of Biological Sciences, Universiti Sains Malaysia, Minden, Penang, Malaysia.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30473529

Citation

Sundarasekar, Jeevandran, et al. "Report: Wound Healing Activity of Hymenocallis Littoralis - Moving Beyond Ornamental Plant." Pakistan Journal of Pharmaceutical Sciences, vol. 31, no. 6, 2018, pp. 2537-2543.
Sundarasekar J, Sahgal G, Murugaiyah V, et al. Report: Wound healing activity of Hymenocallis littoralis - Moving beyond ornamental plant. Pak J Pharm Sci. 2018;31(6):2537-2543.
Sundarasekar, J., Sahgal, G., Murugaiyah, V., Lay, L. K., Thong, O. M., & Subramaniam, S. (2018). Report: Wound healing activity of Hymenocallis littoralis - Moving beyond ornamental plant. Pakistan Journal of Pharmaceutical Sciences, 31(6), 2537-2543.
Sundarasekar J, et al. Report: Wound Healing Activity of Hymenocallis Littoralis - Moving Beyond Ornamental Plant. Pak J Pharm Sci. 2018;31(6):2537-2543. PubMed PMID: 30473529.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Report: Wound healing activity of Hymenocallis littoralis - Moving beyond ornamental plant. AU - Sundarasekar,Jeevandran, AU - Sahgal,Geethaa, AU - Murugaiyah,Vikneswaran, AU - Lay,Lam Kit, AU - Thong,Ong Ming, AU - Subramaniam,Sreeramanan, PY - 2018/11/27/entrez PY - 2018/11/27/pubmed PY - 2019/10/16/medline SP - 2537 EP - 2543 JF - Pakistan journal of pharmaceutical sciences JO - Pak J Pharm Sci VL - 31 IS - 6 N2 - Spider lily (Hymenocallis littoralis) belongs to Amaryllidaceae family is a well-known plant species for its medicinal properties. The inhibitory effects of H. littoralis methanol sonication extracts were evaluated for wound healing activity. This is the first report on the wound healing activity of Malaysian origin H. littoralis. The bulb, flower, root, anther, stem and leaves of H. littoralis methanol sonication extracts were used for scratch-wound assay. The cell line was treated with two different concentrations; 1 and 10μg/ml of extracts. The extracts were prepared freshly by dissolving in sterile phosphate saline buffer (PBS) and the healing activity was observed from 2, 4, 8, 12, 24, 36 and 48 h. The bulb, root, stem and anther methanol extracts demonstrated active wound healing activities at 1 μg mL-1at 36 h of treatment. At the low concentration the bulb, root, stem and anther methanol extracts heals the wound compared to leaf and flower extracts. It's demonstrated that these extracts contain effective phytochemical substances which are responsible for wound healing process. This finding suggests the potential application of H. littoralis methanol extract in wound healing activity. SN - 1011-601X UR - https://www.unboundmedicine.com/medline/citation/30473529/Report:_Wound_healing_activity_of_Hymenocallis_littoralis___Moving_beyond_ornamental_plant_ DB - PRIME DP - Unbound Medicine ER -