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Zuccagnia punctata: A Review of its Traditional Uses; Phytochemistry, Pharmacology and Toxicology.
Nat Prod Commun. 2016 Nov; 11(11):1749-1755.NP

Abstract

Zuccagnia punctata Cav. (Fabaceae, Caesalpiniaceae) is a plant with a long history of use in Argentine traditional medicines; it belongs to a monotypic genus, and is an endemic species of Argentina. This review provides a comprehensive overview of the traditional uses, phytochemistry, pharmacological activity and toxicology of Z. punctata. A wide range of traditional uses are cited in the literature such as antibacterial, antifungal, anti-inflammatory, and antitumor, among - others. Pharmacological studies to date have demonstrated significant activities that support the traditional uses of this plant. No human clinical trials had been - completed up to the time of this review and no toxic effect had been detected in animals. Compounds from different chemical groups have been isolated such las phenolic compounds and essential oils. Plant extracts and phytochemicals isolated exhibit a broad range of activities, anti-inflamnatory, antibacterial, antifungal, antigenotoxic, antioxidant, antiulcer, and nematicidal. The main bioactive phytochemicals in the aerial parts (leaf, stem and flower) were identified as 2', 4'-dihydroxy-3'-methoxychalcone and 2', 4'-dihydroxychalcone and were proposed as chemical markers. Consequently, standardized dry extracts of aerial parts of Z. puntacta could be used in herbal medicinal products. Also, they could be included in phytotherapeutic preparations such as capsules, creams, and gels, and for microencapsulation.

Authors

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Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

30475521

Citation

Isla, María Inés, et al. "Zuccagnia Punctata: a Review of Its Traditional Uses; Phytochemistry, Pharmacology and Toxicology." Natural Product Communications, vol. 11, no. 11, 2016, pp. 1749-1755.
Isla MI, Moreno MA, Nuño G, et al. Zuccagnia punctata: A Review of its Traditional Uses; Phytochemistry, Pharmacology and Toxicology. Nat Prod Commun. 2016;11(11):1749-1755.
Isla, M. I., Moreno, M. A., Nuño, G., Rodriguez, F., Carabajal, A., Alberto, M. R., & Zampini, I. C. (2016). Zuccagnia punctata: A Review of its Traditional Uses; Phytochemistry, Pharmacology and Toxicology. Natural Product Communications, 11(11), 1749-1755.
Isla MI, et al. Zuccagnia Punctata: a Review of Its Traditional Uses; Phytochemistry, Pharmacology and Toxicology. Nat Prod Commun. 2016;11(11):1749-1755. PubMed PMID: 30475521.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Zuccagnia punctata: A Review of its Traditional Uses; Phytochemistry, Pharmacology and Toxicology. AU - Isla,María Inés, AU - Moreno,María Alejandra, AU - Nuño,Gabriela, AU - Rodriguez,Fabiola, AU - Carabajal,Antonella, AU - Alberto,María Rosa, AU - Zampini,Iris Catiana, PY - 2018/11/27/entrez PY - 2016/11/1/pubmed PY - 2019/1/1/medline SP - 1749 EP - 1755 JF - Natural product communications JO - Nat Prod Commun VL - 11 IS - 11 N2 - Zuccagnia punctata Cav. (Fabaceae, Caesalpiniaceae) is a plant with a long history of use in Argentine traditional medicines; it belongs to a monotypic genus, and is an endemic species of Argentina. This review provides a comprehensive overview of the traditional uses, phytochemistry, pharmacological activity and toxicology of Z. punctata. A wide range of traditional uses are cited in the literature such as antibacterial, antifungal, anti-inflammatory, and antitumor, among - others. Pharmacological studies to date have demonstrated significant activities that support the traditional uses of this plant. No human clinical trials had been - completed up to the time of this review and no toxic effect had been detected in animals. Compounds from different chemical groups have been isolated such las phenolic compounds and essential oils. Plant extracts and phytochemicals isolated exhibit a broad range of activities, anti-inflamnatory, antibacterial, antifungal, antigenotoxic, antioxidant, antiulcer, and nematicidal. The main bioactive phytochemicals in the aerial parts (leaf, stem and flower) were identified as 2', 4'-dihydroxy-3'-methoxychalcone and 2', 4'-dihydroxychalcone and were proposed as chemical markers. Consequently, standardized dry extracts of aerial parts of Z. puntacta could be used in herbal medicinal products. Also, they could be included in phytotherapeutic preparations such as capsules, creams, and gels, and for microencapsulation. SN - 1934-578X UR - https://www.unboundmedicine.com/medline/citation/30475521/Zuccagnia_punctata:_A_Review_of_its_Traditional_Uses L2 - https://medlineplus.gov/herbalmedicine.html DB - PRIME DP - Unbound Medicine ER -