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Thalidomide in plasma cell balanitis refractory to conventional topical treatment.
An Bras Dermatol. 2018 Nov/Dec; 93(6):881-883.AB

Abstract

Zoon's plasma cell balanitis is a chronic genital inflammatory dermatosis that affects uncircumcised men, especially the elderly. It's characterized by painless erythematous plaques of orange hue, located on the glans penis and foreskin. Circumcision is the most effective treatment; however, it can be hard for patients to accept. As an alternative, topical calcineurin inhibitors are used, with good response. This article reports the case of a 32-year-old patient, HIV carrier, diagnosed with Zoon's plasma cell balanitis. Treatment with topical tacrolimus was administered, without improvement. A 6-week course of thalidomide resulted in complete remission of the lesions, without recurrence after eight months of follow-up.

Authors+Show Affiliations

Dermatology Service, Hospital Santa Casa de Misericórdia de Vitória, Vitória (ES), Brazil.Dermatology Service, Hospital Santa Casa de Misericórdia de Vitória, Vitória (ES), Brazil.Dermatology Service, Hospital Santa Casa de Misericórdia de Vitória, Vitória (ES), Brazil.Department of Dermatopathology, Hospital Santa Casa de Misericórdia de Vitória, Vitória (ES), Brasil.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

30484535

Citation

Serrão, Lucas Mariano, et al. "Thalidomide in Plasma Cell Balanitis Refractory to Conventional Topical Treatment." Anais Brasileiros De Dermatologia, vol. 93, no. 6, 2018, pp. 881-883.
Serrão LM, Sarmenghi KDA, Pinto BCBP, et al. Thalidomide in plasma cell balanitis refractory to conventional topical treatment. An Bras Dermatol. 2018;93(6):881-883.
Serrão, L. M., Sarmenghi, K. D. A., Pinto, B. C. B. P., & Miranda, P. B. (2018). Thalidomide in plasma cell balanitis refractory to conventional topical treatment. Anais Brasileiros De Dermatologia, 93(6), 881-883. https://doi.org/10.1590/abd1806-4841.20187462
Serrão LM, et al. Thalidomide in Plasma Cell Balanitis Refractory to Conventional Topical Treatment. An Bras Dermatol. 2018 Nov/Dec;93(6):881-883. PubMed PMID: 30484535.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Thalidomide in plasma cell balanitis refractory to conventional topical treatment. AU - Serrão,Lucas Mariano, AU - Sarmenghi,Karina Demoner de Abreu, AU - Pinto,Barbara Christina Bonino Pereira, AU - Miranda,Paulo Bittencourt de, PY - 2017/08/01/received PY - 2018/01/20/accepted PY - 2018/11/29/entrez PY - 2018/11/30/pubmed PY - 2019/2/7/medline SP - 881 EP - 883 JF - Anais brasileiros de dermatologia JO - An Bras Dermatol VL - 93 IS - 6 N2 - Zoon's plasma cell balanitis is a chronic genital inflammatory dermatosis that affects uncircumcised men, especially the elderly. It's characterized by painless erythematous plaques of orange hue, located on the glans penis and foreskin. Circumcision is the most effective treatment; however, it can be hard for patients to accept. As an alternative, topical calcineurin inhibitors are used, with good response. This article reports the case of a 32-year-old patient, HIV carrier, diagnosed with Zoon's plasma cell balanitis. Treatment with topical tacrolimus was administered, without improvement. A 6-week course of thalidomide resulted in complete remission of the lesions, without recurrence after eight months of follow-up. SN - 1806-4841 UR - https://www.unboundmedicine.com/medline/citation/30484535/Thalidomide_in_plasma_cell_balanitis_refractory_to_conventional_topical_treatment_ DB - PRIME DP - Unbound Medicine ER -