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Atypical presentation of necrobiosis lipoidica in a pediatric patient.
Pediatr Dermatol. 2019 Jan; 36(1):e31-e33.PD

Abstract

Necrobiosis lipoidica (NL) is a rare chronic granulomatous inflammatory skin disease characterized by brownish-red papules and yellowish plaques with atrophic centers, which usually affect the legs, bilaterally. The average age of onset is 30-40 years, and there are very few reported cases of necrobiosis lipoidica in children. A nondiabetic girl aged 14 years presented to our clinic with a history of an asymptomatic, 7 × 5-cm single red plaque over her back in the interscapular area, which had started 5 years ago. Her laboratory tests were normal. A histopathologic evaluation confirmed the diagnosis of NL, and local treatment with clobetasol propionate twice daily was administrated. The patient will be followed up to monitor plasma glucose levels and evaluation of the lesion. Herein, we report a pediatric patient without diabetes mellitus who had NL in an atypical location and review the literature in view of the clinical features, complications, and treatment regimens for NL in children.

Authors+Show Affiliations

Dermatology Department, University of Health Sciences, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, Turkey.Pathology Department, University of Health Sciences, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, Turkey.Dermatology Department, University of Health Sciences, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, Turkey.

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

30506892

Citation

Özkur, Ezgi, et al. "Atypical Presentation of Necrobiosis Lipoidica in a Pediatric Patient." Pediatric Dermatology, vol. 36, no. 1, 2019, pp. e31-e33.
Özkur E, Hasçiçek SÖ, Altunay İK. Atypical presentation of necrobiosis lipoidica in a pediatric patient. Pediatr Dermatol. 2019;36(1):e31-e33.
Özkur, E., Hasçiçek, S. Ö., & Altunay, İ. K. (2019). Atypical presentation of necrobiosis lipoidica in a pediatric patient. Pediatric Dermatology, 36(1), e31-e33. https://doi.org/10.1111/pde.13716
Özkur E, Hasçiçek SÖ, Altunay İK. Atypical Presentation of Necrobiosis Lipoidica in a Pediatric Patient. Pediatr Dermatol. 2019;36(1):e31-e33. PubMed PMID: 30506892.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Atypical presentation of necrobiosis lipoidica in a pediatric patient. AU - Özkur,Ezgi, AU - Hasçiçek,Seyhan Ö, AU - Altunay,İlknur Kıvanç, Y1 - 2018/12/02/ PY - 2018/12/7/pubmed PY - 2019/2/7/medline PY - 2018/12/4/entrez KW - granulomatous KW - necrobiosis KW - necrobiosis lipoidica SP - e31 EP - e33 JF - Pediatric dermatology JO - Pediatr Dermatol VL - 36 IS - 1 N2 - Necrobiosis lipoidica (NL) is a rare chronic granulomatous inflammatory skin disease characterized by brownish-red papules and yellowish plaques with atrophic centers, which usually affect the legs, bilaterally. The average age of onset is 30-40 years, and there are very few reported cases of necrobiosis lipoidica in children. A nondiabetic girl aged 14 years presented to our clinic with a history of an asymptomatic, 7 × 5-cm single red plaque over her back in the interscapular area, which had started 5 years ago. Her laboratory tests were normal. A histopathologic evaluation confirmed the diagnosis of NL, and local treatment with clobetasol propionate twice daily was administrated. The patient will be followed up to monitor plasma glucose levels and evaluation of the lesion. Herein, we report a pediatric patient without diabetes mellitus who had NL in an atypical location and review the literature in view of the clinical features, complications, and treatment regimens for NL in children. SN - 1525-1470 UR - https://www.unboundmedicine.com/medline/citation/30506892/Atypical_presentation_of_necrobiosis_lipoidica_in_a_pediatric_patient_ L2 - https://doi.org/10.1111/pde.13716 DB - PRIME DP - Unbound Medicine ER -