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The effectiveness of topical therapy combined with 308-nm excimer laser on vitiligo compared to excimer laser monotherapy in pediatric patients.
Pediatr Dermatol. 2019 Jan; 36(1):e53-e55.PD

Abstract

We evaluated the efficiency of using a 308-nm excimer laser with either tacrolimus, pimecrolimus, or halometasone for the treatment of childhood vitiligo. Patients who received combined treatments had significantly higher rates of repigmentation in comparison with individuals who underwent excimer laser alone therapy. Moreover, patients who received treatment with excimer laser and halometasone had significantly higher rates of repigmentation, even higher than individuals who were treated with tacrolimus combined or pimecrolimus combined. This regimen was more effective on the face, neck, and limbs. We conclude that the use of a combined excimer laser and halometasone cream has a greater therapeutic effect than laser alone.

Authors+Show Affiliations

Department of Dermatology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.Department of Dermatology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.Department of Dermatology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.Department of Dermatology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.Department of Dermatology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.Department of Dermatology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

30520111

Citation

Li, Lili, et al. "The Effectiveness of Topical Therapy Combined With 308-nm Excimer Laser On Vitiligo Compared to Excimer Laser Monotherapy in Pediatric Patients." Pediatric Dermatology, vol. 36, no. 1, 2019, pp. e53-e55.
Li L, Liang Y, Hong J, et al. The effectiveness of topical therapy combined with 308-nm excimer laser on vitiligo compared to excimer laser monotherapy in pediatric patients. Pediatr Dermatol. 2019;36(1):e53-e55.
Li, L., Liang, Y., Hong, J., Lan, L., Xiao, H., & Xie, Z. (2019). The effectiveness of topical therapy combined with 308-nm excimer laser on vitiligo compared to excimer laser monotherapy in pediatric patients. Pediatric Dermatology, 36(1), e53-e55. https://doi.org/10.1111/pde.13726
Li L, et al. The Effectiveness of Topical Therapy Combined With 308-nm Excimer Laser On Vitiligo Compared to Excimer Laser Monotherapy in Pediatric Patients. Pediatr Dermatol. 2019;36(1):e53-e55. PubMed PMID: 30520111.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The effectiveness of topical therapy combined with 308-nm excimer laser on vitiligo compared to excimer laser monotherapy in pediatric patients. AU - Li,Lili, AU - Liang,Yanping, AU - Hong,Jiqiong, AU - Lan,Lizhen, AU - Xiao,Hewei, AU - Xie,Zhi, Y1 - 2018/12/05/ PY - 2018/12/7/pubmed PY - 2019/2/7/medline PY - 2018/12/7/entrez KW - 308-nm excimer laser KW - halometasone KW - pimecrolimus KW - tacrolimus KW - vitiligo SP - e53 EP - e55 JF - Pediatric dermatology JO - Pediatr Dermatol VL - 36 IS - 1 N2 - We evaluated the efficiency of using a 308-nm excimer laser with either tacrolimus, pimecrolimus, or halometasone for the treatment of childhood vitiligo. Patients who received combined treatments had significantly higher rates of repigmentation in comparison with individuals who underwent excimer laser alone therapy. Moreover, patients who received treatment with excimer laser and halometasone had significantly higher rates of repigmentation, even higher than individuals who were treated with tacrolimus combined or pimecrolimus combined. This regimen was more effective on the face, neck, and limbs. We conclude that the use of a combined excimer laser and halometasone cream has a greater therapeutic effect than laser alone. SN - 1525-1470 UR - https://www.unboundmedicine.com/medline/citation/30520111/The_effectiveness_of_topical_therapy_combined_with_308_nm_excimer_laser_on_vitiligo_compared_to_excimer_laser_monotherapy_in_pediatric_patients_ L2 - https://doi.org/10.1111/pde.13726 DB - PRIME DP - Unbound Medicine ER -