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Labetalol
StatPearls. StatPearls Publishing: Treasure Island (FL).BOOK

Abstract
Due to their negative inotropic and chronotropic actions, beta-adrenergic receptor antagonists are typically indicated in individuals with chronic cardiovascular disease (hypertension, coronary artery disease, congestive heart failure) with a significant reduction in mortality. The FDA-approved indication for labetalol is to treat arterial hypertension, which ranges from acute hypertensive crises (urgent/emergency) to stable chronic hypertension. Labetalol in clinical practice has several common off-label uses that include acute hypertension in pregnancy and hypertension associated with acute ischemic stroke, and intracranial hemorrhage, including subarachnoid hemorrhage. Today, labetalol is usually reserved for the acute management of hypertensive crises. This activity covers labetalol, including mechanism of action, pharmacology, adverse event profiles, eligible patient populations, contraindications, monitoring, and highlights the role of the interprofessional team in the management of labetalol therapy.

Publisher

StatPearls Publishing
Treasure Island (FL)

Language

eng

PubMed ID

30521208

Citation

Miller M, Kerndt CC, Maani CV: Labetalol. StatPearls. StatPearls Publishing, 2021, Treasure Island (FL).
Miller M, Kerndt CC, Maani CV. Labetalol. StatPearls. StatPearls Publishing; 2021.
Miller M & Kerndt CC & Maani CV. (2021). Labetalol. In StatPearls. Treasure Island (FL): StatPearls Publishing
Miller M, Kerndt CC, Maani CV. Labetalol. StatPearls. Treasure Island (FL): StatPearls Publishing; 2021.
* Article titles in AMA citation format should be in sentence-case
TY - CHAP T1 - Labetalol BT - StatPearls A1 - Miller,Michael, AU - Kerndt,Connor C., AU - Maani,Christopher V., Y1 - 2021/01// PY - 2018/12/7/pubmed PY - 2018/12/7/medline PY - 2018/12/7/entrez N2 - Due to their negative inotropic and chronotropic actions, beta-adrenergic receptor antagonists are typically indicated in individuals with chronic cardiovascular disease (hypertension, coronary artery disease, congestive heart failure) with a significant reduction in mortality. The FDA-approved indication for labetalol is to treat arterial hypertension, which ranges from acute hypertensive crises (urgent/emergency) to stable chronic hypertension. Labetalol in clinical practice has several common off-label uses that include acute hypertension in pregnancy and hypertension associated with acute ischemic stroke, and intracranial hemorrhage, including subarachnoid hemorrhage. Today, labetalol is usually reserved for the acute management of hypertensive crises. This activity covers labetalol, including mechanism of action, pharmacology, adverse event profiles, eligible patient populations, contraindications, monitoring, and highlights the role of the interprofessional team in the management of labetalol therapy. PB - StatPearls Publishing CY - Treasure Island (FL) UR - https://www.unboundmedicine.com/medline/citation/30521208/StatPearls:_Labetalol L2 - https://www.ncbi.nlm.nih.gov/books/NBK534787 DB - PRIME DP - Unbound Medicine ER -
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