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Schizophrenia in microcephalic osteodysplastic primordial dwarfism type II syndrome: supporting evidence for an association between the PCNT gene and schizophrenia.
Psychiatr Genet 2019; 29(2):57-60PG

Abstract

Schizophrenia is a genetically complex disease that is related to neurodevelopmental abnormalities. Several genetic polymorphisms and genetic syndromes associated with neurodevelopmental processes have been linked to schizophrenia. In this case report, we present a case with an association between microcephalic osteodysplastic primordial dwarfism type II and schizophrenia. Microcephalic osteodysplastic primordial dwarfism type II syndrome is a rare, autosomal recessive disease that occurs as a result of the mutations in the pericentrin (PCNT) gene that are responsible for cell cycle and division. In this report, we discuss the possible association between the PCNT gene and schizophrenia.

Authors+Show Affiliations

Departments of Psychiatry.Departments of Psychiatry.Pediatrics, Division of Genetics.Pediatrics, Division of Genetics.Department of Radiology, Dokuz Eylul University, Izmir, Turkey.Departments of Psychiatry.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

30531648

Citation

Ozel, Fatih, et al. "Schizophrenia in Microcephalic Osteodysplastic Primordial Dwarfism Type II Syndrome: Supporting Evidence for an Association Between the PCNT Gene and Schizophrenia." Psychiatric Genetics, vol. 29, no. 2, 2019, pp. 57-60.
Ozel F, Direk N, Ataseven Kulali M, et al. Schizophrenia in microcephalic osteodysplastic primordial dwarfism type II syndrome: supporting evidence for an association between the PCNT gene and schizophrenia. Psychiatr Genet. 2019;29(2):57-60.
Ozel, F., Direk, N., Ataseven Kulali, M., Giray Bozkaya, O., Ada, E., & Alptekin, K. (2019). Schizophrenia in microcephalic osteodysplastic primordial dwarfism type II syndrome: supporting evidence for an association between the PCNT gene and schizophrenia. Psychiatric Genetics, 29(2), pp. 57-60. doi:10.1097/YPG.0000000000000214.
Ozel F, et al. Schizophrenia in Microcephalic Osteodysplastic Primordial Dwarfism Type II Syndrome: Supporting Evidence for an Association Between the PCNT Gene and Schizophrenia. Psychiatr Genet. 2019;29(2):57-60. PubMed PMID: 30531648.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Schizophrenia in microcephalic osteodysplastic primordial dwarfism type II syndrome: supporting evidence for an association between the PCNT gene and schizophrenia. AU - Ozel,Fatih, AU - Direk,Nese, AU - Ataseven Kulali,Melike, AU - Giray Bozkaya,Ozlem, AU - Ada,Emel, AU - Alptekin,Koksal, PY - 2018/12/12/pubmed PY - 2019/3/16/medline PY - 2018/12/12/entrez SP - 57 EP - 60 JF - Psychiatric genetics JO - Psychiatr. Genet. VL - 29 IS - 2 N2 - Schizophrenia is a genetically complex disease that is related to neurodevelopmental abnormalities. Several genetic polymorphisms and genetic syndromes associated with neurodevelopmental processes have been linked to schizophrenia. In this case report, we present a case with an association between microcephalic osteodysplastic primordial dwarfism type II and schizophrenia. Microcephalic osteodysplastic primordial dwarfism type II syndrome is a rare, autosomal recessive disease that occurs as a result of the mutations in the pericentrin (PCNT) gene that are responsible for cell cycle and division. In this report, we discuss the possible association between the PCNT gene and schizophrenia. SN - 1473-5873 UR - https://www.unboundmedicine.com/medline/citation/30531648/Schizophrenia_in_microcephalic_osteodysplastic_primordial_dwarfism_type_II_syndrome:_supporting_evidence_for_an_association_between_the_PCNT_gene_and_schizophrenia_ L2 - http://Insights.ovid.com/pubmed?pmid=30531648 DB - PRIME DP - Unbound Medicine ER -