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Immunohistochemical study of the local humoral immune system of the equine respiratory mucosa.
Res Vet Sci. 1988 Sep; 45(2):160-5.RV

Abstract

An indirect immunoperoxidase technique was used to demonstrate both free immunoglobulin and immunoglobulin-containing plasma cells of IgG, IgA, and IgM classes in the mucosa of the equine respiratory tract. IgA-producing plasma cells predominated in the upper airways, whereas IgG-producing cells predominated in the lower respiratory tract. IgM-secreting cells were uncommon, but present in their highest numbers in the nasopharynx. Plasma cells specific for all of the immunoglobulin classes were identified in the surface epithelium, lamina propria connective tissue, glandular tissue and organised lymphoid tissue. The surface epithelium stained strongly for free IgA and IgM, but weakly for IgG, whereas glandular cells and the lamina propria connective tissue stained most strongly for IgG.

Authors+Show Affiliations

Department of Veterinary Medicine, University of Bristol, School of Veterinary Science, Langford.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3057548

Citation

Mair, T S., et al. "Immunohistochemical Study of the Local Humoral Immune System of the Equine Respiratory Mucosa." Research in Veterinary Science, vol. 45, no. 2, 1988, pp. 160-5.
Mair TS, Stokes CR, Bourne FJ. Immunohistochemical study of the local humoral immune system of the equine respiratory mucosa. Res Vet Sci. 1988;45(2):160-5.
Mair, T. S., Stokes, C. R., & Bourne, F. J. (1988). Immunohistochemical study of the local humoral immune system of the equine respiratory mucosa. Research in Veterinary Science, 45(2), 160-5.
Mair TS, Stokes CR, Bourne FJ. Immunohistochemical Study of the Local Humoral Immune System of the Equine Respiratory Mucosa. Res Vet Sci. 1988;45(2):160-5. PubMed PMID: 3057548.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Immunohistochemical study of the local humoral immune system of the equine respiratory mucosa. AU - Mair,T S, AU - Stokes,C R, AU - Bourne,F J, PY - 1988/9/1/pubmed PY - 1988/9/1/medline PY - 1988/9/1/entrez SP - 160 EP - 5 JF - Research in veterinary science JO - Res. Vet. Sci. VL - 45 IS - 2 N2 - An indirect immunoperoxidase technique was used to demonstrate both free immunoglobulin and immunoglobulin-containing plasma cells of IgG, IgA, and IgM classes in the mucosa of the equine respiratory tract. IgA-producing plasma cells predominated in the upper airways, whereas IgG-producing cells predominated in the lower respiratory tract. IgM-secreting cells were uncommon, but present in their highest numbers in the nasopharynx. Plasma cells specific for all of the immunoglobulin classes were identified in the surface epithelium, lamina propria connective tissue, glandular tissue and organised lymphoid tissue. The surface epithelium stained strongly for free IgA and IgM, but weakly for IgG, whereas glandular cells and the lamina propria connective tissue stained most strongly for IgG. SN - 0034-5288 UR - https://www.unboundmedicine.com/medline/citation/3057548/Immunohistochemical_study_of_the_local_humoral_immune_system_of_the_equine_respiratory_mucosa_ DB - PRIME DP - Unbound Medicine ER -