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Haemato-immunological studies in ZnO and TiO2 nanoparticles exposed euryhaline fish, Oreochromis mossambicus.
Environ Toxicol Pharmacol. 2019 Feb; 66:55-61.ET

Abstract

The present study was aimed to analyze the effect of ZnO and TiO2 nanoparticles (NPs) on Haemato-immunological parameters in adult Tilapia, Oreochromis mossambicus. The nanoparticles size found as 47 nm and 30 nm for ZnO and TiO2 respectively. The acute toxicity (96 h) of ZnO (LC50: 100-110 ppm) and TiO2 (LC50: 80-90 ppm) NPs were identified by using probit analysis. RBC, Hb and HCT levels decreased in nanoparticles exposed groups resulted in decreased oxygen carrying capacity of RBC and other erythrocyte indices (MCH, MCV, MCHC). Increased WBC, neutrophils & monocytes and decreased lymphocyte levels were observed as increased concentration of the nanoparticles. The results were found as statistically significant (p < 0.05). In conclusion, the present study depicts that ZnO NPs exhibits more toxicity than TiO2 NPs. Nanoparticles presence even in low concentration (ppm) cause damage to the connective tissues of fish, so the existing permissible levels of these nanoparticles in water are need to be revised.

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Authors+Show Affiliations

Suganthi P
Environmental Research Laboratory, P.G. and Research Department of Zoology, Jamal Mohamed College (Autonomous), Tiruchirappalli 620020, Tamil Nadu, India.
Murali M
Environmental Research Laboratory, P.G. and Research Department of Zoology, Jamal Mohamed College (Autonomous), Tiruchirappalli 620020, Tamil Nadu, India.
Athif P
Environmental Research Laboratory, P.G. and Research Department of Zoology, Jamal Mohamed College (Autonomous), Tiruchirappalli 620020, Tamil Nadu, India.
Sadiq Bukhari A
Environmental Research Laboratory, P.G. and Research Department of Zoology, Jamal Mohamed College (Autonomous), Tiruchirappalli 620020, Tamil Nadu, India. Electronic address: abjmc@yahoo.in.
Syed Mohamed HE
Environmental Research Laboratory, P.G. and Research Department of Zoology, Jamal Mohamed College (Autonomous), Tiruchirappalli 620020, Tamil Nadu, India.
Basu H
Analytical Spectroscopy Section, Analytical Chemistry Division, Bhabha Atomic Research Center, Trombay, Mumbai 400085, India.
Singhal RK
Analytical Spectroscopy Section, Analytical Chemistry Division, Bhabha Atomic Research Center, Trombay, Mumbai 400085, India.

MeSH

AnimalsFemaleHematologic TestsLethal Dose 50MaleNanoparticlesTilapiaTitaniumWater Pollutants, ChemicalZinc Oxide

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30597380

Citation

Suganthi, P, et al. "Haemato-immunological Studies in ZnO and TiO2 Nanoparticles Exposed Euryhaline Fish, Oreochromis Mossambicus." Environmental Toxicology and Pharmacology, vol. 66, 2019, pp. 55-61.
Suganthi P, Murali M, Athif P, et al. Haemato-immunological studies in ZnO and TiO2 nanoparticles exposed euryhaline fish, Oreochromis mossambicus. Environ Toxicol Pharmacol. 2019;66:55-61.
Suganthi, P., Murali, M., Athif, P., Sadiq Bukhari, A., Syed Mohamed, H. E., Basu, H., & Singhal, R. K. (2019). Haemato-immunological studies in ZnO and TiO2 nanoparticles exposed euryhaline fish, Oreochromis mossambicus. Environmental Toxicology and Pharmacology, 66, 55-61. https://doi.org/10.1016/j.etap.2018.12.011
Suganthi P, et al. Haemato-immunological Studies in ZnO and TiO2 Nanoparticles Exposed Euryhaline Fish, Oreochromis Mossambicus. Environ Toxicol Pharmacol. 2019;66:55-61. PubMed PMID: 30597380.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Haemato-immunological studies in ZnO and TiO2 nanoparticles exposed euryhaline fish, Oreochromis mossambicus. AU - Suganthi,P, AU - Murali,M, AU - Athif,P, AU - Sadiq Bukhari,A, AU - Syed Mohamed,H E, AU - Basu,H, AU - Singhal,R K, Y1 - 2018/12/19/ PY - 2018/06/04/received PY - 2018/11/27/revised PY - 2018/12/17/accepted PY - 2019/1/1/pubmed PY - 2019/3/12/medline PY - 2019/1/1/entrez KW - Immunology KW - O. mossambicus haematology KW - TiO(2) KW - ZnO SP - 55 EP - 61 JF - Environmental toxicology and pharmacology JO - Environ Toxicol Pharmacol VL - 66 N2 - The present study was aimed to analyze the effect of ZnO and TiO2 nanoparticles (NPs) on Haemato-immunological parameters in adult Tilapia, Oreochromis mossambicus. The nanoparticles size found as 47 nm and 30 nm for ZnO and TiO2 respectively. The acute toxicity (96 h) of ZnO (LC50: 100-110 ppm) and TiO2 (LC50: 80-90 ppm) NPs were identified by using probit analysis. RBC, Hb and HCT levels decreased in nanoparticles exposed groups resulted in decreased oxygen carrying capacity of RBC and other erythrocyte indices (MCH, MCV, MCHC). Increased WBC, neutrophils & monocytes and decreased lymphocyte levels were observed as increased concentration of the nanoparticles. The results were found as statistically significant (p < 0.05). In conclusion, the present study depicts that ZnO NPs exhibits more toxicity than TiO2 NPs. Nanoparticles presence even in low concentration (ppm) cause damage to the connective tissues of fish, so the existing permissible levels of these nanoparticles in water are need to be revised. SN - 1872-7077 UR - https://www.unboundmedicine.com/medline/citation/30597380/Haemato_immunological_studies_in_ZnO_and_TiO2_nanoparticles_exposed_euryhaline_fish_Oreochromis_mossambicus_ DB - PRIME DP - Unbound Medicine ER -