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Chromane Enantiomers from the Flower Buds of Tussilago farfara L. and Assignments of Their Absolute Configurations.
Chem Biodivers. 2019 Mar; 16(3):e1800581.CB

Abstract

Fourteen chromane derivatives of seven pairs of enantiomers (1-14) have been obtained from the ethanolic extract of the flower buds of Tussilago farfara L. Their structures with absolute configurations have been elucidated by detailed spectroscopic analyses, chemical methods, and particularly comparison of experimental ECD spectra with theoretically computed ones. Biological evaluations revealed that they did not show cytoprotective, antimicrobial, and α-glucosidase inhibitory activities.

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Authors+Show Affiliations

Sun J
School of Chemistry and Chemical Engineering, University of Jinan, 336 West Road of Nan Xinzhuang, Jinan, 250022, P. R. China. School of Biological Science and Technology, University of Jinan, 336 West Road of Nan Xinzhuang, Jinan, 250022, P. R. China.
Yu JH
School of Biological Science and Technology, University of Jinan, 336 West Road of Nan Xinzhuang, Jinan, 250022, P. R. China.
Zhang JS
School of Biological Science and Technology, University of Jinan, 336 West Road of Nan Xinzhuang, Jinan, 250022, P. R. China.
Song XQ
School of Chemistry and Chemical Engineering, University of Jinan, 336 West Road of Nan Xinzhuang, Jinan, 250022, P. R. China. School of Biological Science and Technology, University of Jinan, 336 West Road of Nan Xinzhuang, Jinan, 250022, P. R. China.
Bao J
School of Biological Science and Technology, University of Jinan, 336 West Road of Nan Xinzhuang, Jinan, 250022, P. R. China.
Zhang H
School of Biological Science and Technology, University of Jinan, 336 West Road of Nan Xinzhuang, Jinan, 250022, P. R. China.

MeSH

ChromansDensity Functional TheoryFlowersHumansMolecular ConformationPlant ExtractsPlant RootsStereoisomerismTumor Cells, CulturedTussilago

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30600902

Citation

Sun, Jia, et al. "Chromane Enantiomers From the Flower Buds of Tussilago Farfara L. and Assignments of Their Absolute Configurations." Chemistry & Biodiversity, vol. 16, no. 3, 2019, pp. e1800581.
Sun J, Yu JH, Zhang JS, et al. Chromane Enantiomers from the Flower Buds of Tussilago farfara L. and Assignments of Their Absolute Configurations. Chem Biodivers. 2019;16(3):e1800581.
Sun, J., Yu, J. H., Zhang, J. S., Song, X. Q., Bao, J., & Zhang, H. (2019). Chromane Enantiomers from the Flower Buds of Tussilago farfara L. and Assignments of Their Absolute Configurations. Chemistry & Biodiversity, 16(3), e1800581. https://doi.org/10.1002/cbdv.201800581
Sun J, et al. Chromane Enantiomers From the Flower Buds of Tussilago Farfara L. and Assignments of Their Absolute Configurations. Chem Biodivers. 2019;16(3):e1800581. PubMed PMID: 30600902.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chromane Enantiomers from the Flower Buds of Tussilago farfara L. and Assignments of Their Absolute Configurations. AU - Sun,Jia, AU - Yu,Jin-Hai, AU - Zhang,Jun-Sheng, AU - Song,Xiu-Qing, AU - Bao,Jie, AU - Zhang,Hua, Y1 - 2019/02/25/ PY - 2018/11/05/received PY - 2018/12/27/accepted PY - 2019/1/3/pubmed PY - 2019/5/29/medline PY - 2019/1/3/entrez KW - ECD calculation KW - Tussilago farfara L. KW - biological activity KW - chromane KW - natural enantiomer KW - phytochemistry SP - e1800581 EP - e1800581 JF - Chemistry & biodiversity JO - Chem Biodivers VL - 16 IS - 3 N2 - Fourteen chromane derivatives of seven pairs of enantiomers (1-14) have been obtained from the ethanolic extract of the flower buds of Tussilago farfara L. Their structures with absolute configurations have been elucidated by detailed spectroscopic analyses, chemical methods, and particularly comparison of experimental ECD spectra with theoretically computed ones. Biological evaluations revealed that they did not show cytoprotective, antimicrobial, and α-glucosidase inhibitory activities. SN - 1612-1880 UR - https://www.unboundmedicine.com/medline/citation/30600902/Chromane_Enantiomers_from_the_Flower_Buds_of_Tussilago_farfara_L__and_Assignments_of_Their_Absolute_Configurations_ DB - PRIME DP - Unbound Medicine ER -