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Effect of a mixture of botanicals extracts plus mannitol on hydration and bloating sensation. An open label study in women with high extra cellular water.
Nat Prod Res 2019; :1-5NP

Abstract

The aim of the study is to evaluate the effectiveness of of 4 and 8 week supplementation with highly standardized formula with Fraxinus ornus L., plus Ananas comosus L., concentrated juice, Betula pendula R., Equisetum arvense L., Urtica dioica L. and Pilosella officinarum L. Vail dry extract, on the state of hydration and bloating sensation in subjects with high and moderate extra cellular water (ECW). 19 women (mean age 35 yr and Body Mass Index 22.82 kg\m2) with Extra Cellular Water over 45%completed the study and their data were analysed at baseline, at 30 and 60 days. Bio-impedance, SF36 and anthropometric parameters were assessed. The ECW decreased of -1.97% (at 30 days) and -2.30% (60 days) (p < 0.01). Also fat mass decreased of -1.58% (at 30 days) and -2.21% (60 days) (p = 0.057). An improvement of free fat mass was assessed (p < 0.05) but not on bloating sensation questionnaire at 60 days (p = 0.422).

Authors+Show Affiliations

a Department of Biology College of Science , University of Bahrain , Sakhir Campus , Sakhir , Kingdom of Bahrain.b San Marino Republic , PromoPharma S.p.A. Acquaviva , San Marino , Italy.b San Marino Republic , PromoPharma S.p.A. Acquaviva , San Marino , Italy.b San Marino Republic , PromoPharma S.p.A. Acquaviva , San Marino , Italy.c Department of Public Health Experimental and Forensic Medicine Unit of Human and Clinical Nutrition , University of Pavia , Pavia , Italy.c Department of Public Health Experimental and Forensic Medicine Unit of Human and Clinical Nutrition , University of Pavia , Pavia , Italy. d IRCCS Mondino Foundation, Pavia.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30602313

Citation

Perna, Simone, et al. "Effect of a Mixture of Botanicals Extracts Plus Mannitol On Hydration and Bloating Sensation. an Open Label Study in Women With High Extra Cellular Water." Natural Product Research, 2019, pp. 1-5.
Perna S, Biserni M, Borsani F, et al. Effect of a mixture of botanicals extracts plus mannitol on hydration and bloating sensation. An open label study in women with high extra cellular water. Nat Prod Res. 2019.
Perna, S., Biserni, M., Borsani, F., Berardi, M., Spadaccini, D., & Rondanelli, M. (2019). Effect of a mixture of botanicals extracts plus mannitol on hydration and bloating sensation. An open label study in women with high extra cellular water. Natural Product Research, pp. 1-5. doi:10.1080/14786419.2018.1539975.
Perna S, et al. Effect of a Mixture of Botanicals Extracts Plus Mannitol On Hydration and Bloating Sensation. an Open Label Study in Women With High Extra Cellular Water. Nat Prod Res. 2019 Jan 3;1-5. PubMed PMID: 30602313.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of a mixture of botanicals extracts plus mannitol on hydration and bloating sensation. An open label study in women with high extra cellular water. AU - Perna,Simone, AU - Biserni,Manuela, AU - Borsani,Filippo, AU - Berardi,Martina, AU - Spadaccini,Daniele, AU - Rondanelli,Mariangela, Y1 - 2019/01/03/ PY - 2019/1/4/entrez KW - Mannitol KW - bloating sensation KW - cellulitis KW - extra cellular water KW - water retention SP - 1 EP - 5 JF - Natural product research JO - Nat. Prod. Res. N2 - The aim of the study is to evaluate the effectiveness of of 4 and 8 week supplementation with highly standardized formula with Fraxinus ornus L., plus Ananas comosus L., concentrated juice, Betula pendula R., Equisetum arvense L., Urtica dioica L. and Pilosella officinarum L. Vail dry extract, on the state of hydration and bloating sensation in subjects with high and moderate extra cellular water (ECW). 19 women (mean age 35 yr and Body Mass Index 22.82 kg\m2) with Extra Cellular Water over 45%completed the study and their data were analysed at baseline, at 30 and 60 days. Bio-impedance, SF36 and anthropometric parameters were assessed. The ECW decreased of -1.97% (at 30 days) and -2.30% (60 days) (p < 0.01). Also fat mass decreased of -1.58% (at 30 days) and -2.21% (60 days) (p = 0.057). An improvement of free fat mass was assessed (p < 0.05) but not on bloating sensation questionnaire at 60 days (p = 0.422). SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/30602313/Effect_of_a_mixture_of_botanicals_extracts_plus_mannitol_on_hydration_and_bloating_sensation._An_open_label_study_in_women_with_high_extra_cellular_water L2 - http://www.tandfonline.com/doi/full/10.1080/14786419.2018.1539975 DB - PRIME DP - Unbound Medicine ER -