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Cannabis and Turmeric as Complementary Treatments for IBD and Other Digestive Diseases.
Curr Gastroenterol Rep. 2019 Jan 11; 21(2):2.CG

Abstract

PURPOSE OF REVIEW

Complementary therapies for inflammatory bowel disease (IBD) have earned growing interest from patients and investigators alike, with a dynamic landscape of research in this area. In this article, we review results of the most recent studies evaluating the role of cannabis and turmeric for the treatment of IBD and other intestinal illnesses.

RECENT FINDINGS

Cannabinoids are well-established modulators of gut motility and visceral pain and have demonstrated anti-inflammatory properties. Clinical trials suggest that there may be a therapeutic role for cannabinoid therapy in the treatment of IBD, irritable bowel syndrome (IBS), nausea and vomiting, and GI motility disorders. Recent reports of serious adverse effects from synthetic cannabinoids highlight the need for additional investigation of cannabinoids to establish their efficacy and safety. Turmeric trials have demonstrated some promise as adjuvant treatment for IBD, though not in other GI disease processes. Evidence suggests that the use of cannabis and turmeric is potentially beneficial in IBD and IBS; however, neither has been compared to standard therapy in IBD, and thus should not be recommended as alternative treatment for IBD. For cannabis in particular, additional investigation regarding appropriate dosing and timing, given known adverse effects of its chronic use, and careful monitoring of potential bleeding complications with synthetic cannabinoids are imperative.

Authors+Show Affiliations

Department of Medicine, Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. squezada@som.umaryland.edu.Department of Medicine, Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

30635796

Citation

Quezada, Sandra M., and Raymond K. Cross. "Cannabis and Turmeric as Complementary Treatments for IBD and Other Digestive Diseases." Current Gastroenterology Reports, vol. 21, no. 2, 2019, p. 2.
Quezada SM, Cross RK. Cannabis and Turmeric as Complementary Treatments for IBD and Other Digestive Diseases. Curr Gastroenterol Rep. 2019;21(2):2.
Quezada, S. M., & Cross, R. K. (2019). Cannabis and Turmeric as Complementary Treatments for IBD and Other Digestive Diseases. Current Gastroenterology Reports, 21(2), 2. https://doi.org/10.1007/s11894-019-0670-0
Quezada SM, Cross RK. Cannabis and Turmeric as Complementary Treatments for IBD and Other Digestive Diseases. Curr Gastroenterol Rep. 2019 Jan 11;21(2):2. PubMed PMID: 30635796.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cannabis and Turmeric as Complementary Treatments for IBD and Other Digestive Diseases. AU - Quezada,Sandra M, AU - Cross,Raymond K, Y1 - 2019/01/11/ PY - 2019/1/13/entrez PY - 2019/1/13/pubmed PY - 2019/5/29/medline KW - Cannabinoids KW - Cannabis KW - Complementary therapy KW - Curcumin KW - Inflammatory bowel disease KW - Turmeric SP - 2 EP - 2 JF - Current gastroenterology reports JO - Curr Gastroenterol Rep VL - 21 IS - 2 N2 - PURPOSE OF REVIEW: Complementary therapies for inflammatory bowel disease (IBD) have earned growing interest from patients and investigators alike, with a dynamic landscape of research in this area. In this article, we review results of the most recent studies evaluating the role of cannabis and turmeric for the treatment of IBD and other intestinal illnesses. RECENT FINDINGS: Cannabinoids are well-established modulators of gut motility and visceral pain and have demonstrated anti-inflammatory properties. Clinical trials suggest that there may be a therapeutic role for cannabinoid therapy in the treatment of IBD, irritable bowel syndrome (IBS), nausea and vomiting, and GI motility disorders. Recent reports of serious adverse effects from synthetic cannabinoids highlight the need for additional investigation of cannabinoids to establish their efficacy and safety. Turmeric trials have demonstrated some promise as adjuvant treatment for IBD, though not in other GI disease processes. Evidence suggests that the use of cannabis and turmeric is potentially beneficial in IBD and IBS; however, neither has been compared to standard therapy in IBD, and thus should not be recommended as alternative treatment for IBD. For cannabis in particular, additional investigation regarding appropriate dosing and timing, given known adverse effects of its chronic use, and careful monitoring of potential bleeding complications with synthetic cannabinoids are imperative. SN - 1534-312X UR - https://www.unboundmedicine.com/medline/citation/30635796/Cannabis_and_Turmeric_as_Complementary_Treatments_for_IBD_and_Other_Digestive_Diseases_ L2 - https://dx.doi.org/10.1007/s11894-019-0670-0 DB - PRIME DP - Unbound Medicine ER -