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Visual outcomes after cataract surgery in patients with type 2 diabetes.
J Cataract Refract Surg. 2019 04; 45(4):404-413.JC

Abstract

PURPOSE

To assess the relation between diabetic retinopathy (DR) severity, duration of diabetes, insulin dependence, and preoperative hemoglobin A1c (HbA1c) with visual outcome after phacoemulsification for cataract in patients with type 2 diabetes.

SETTING

Kaiser Permanente Northern California, USA.

DESIGN

Retrospective case series.

METHODS

Information was obtained from the electronic medical record for patients, June 1, 2010, through May 31, 2015. Confounding factors and clustering of eyes within patients were controlled for using linear mixed-effects regression models for continuous outcomes and general estimating equations for dichotomous outcomes.

RESULTS

The study included 65 370 patients; 28% had type 2 diabetes without DR, 5% nonproliferative DR, and 1.2% proliferative DR. Patients with diabetes and no DR were as likely as those without diabetes to achieve a corrected distance visual acuity (CDVA) of 20/20 (odds ratio, 1.01; 95% confidence interval, 0.94-1.10). The odds of a postoperative CDVA of 20/25 or worse increased with the severity of retinopathy duration of diabetes and insulin dependence, but not with the preoperative HbA1c. Although the odds of a postoperative CDVA of 20/20 was lower in patients with DR, every DR group averaged 4 lines of CDVA improvement, the same as patients without diabetes. A longer duration of diabetes, insulin dependence, and elevated HbA1c were not associated with worse postoperative outcomes.

CONCLUSION

Patients with DR and cataracts were less likely to achieve a CDVA of 20/20 vision but gained as many lines of CDVA from phacoemulsification as patients without diabetes, showing no evidence that cataract surgery should be delayed in diabetic patients with elevated HbA1c.

Authors+Show Affiliations

Division of Research, Kaiser Permanente Northern California, Oakland, USA.Division of Research, Kaiser Permanente Northern California, Oakland, USA. Electronic address: lisa.herrinton@kp.org.Division of Research, Kaiser Permanente Northern California, Oakland, USA.Division of Research, Kaiser Permanente Northern California, Oakland, USA.Division of Research, Kaiser Permanente Northern California, Oakland, USA.Department of Ophthalmology, Kaiser Permanente, San Rafael, California, USA.Departments of Ophthalmology and Quality, Kaiser Permanente, Walnut Creek, California, USA.

Pub Type(s)

Journal Article
Multicenter Study
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

30638823

Citation

Liu, Liyan, et al. "Visual Outcomes After Cataract Surgery in Patients With Type 2 Diabetes." Journal of Cataract and Refractive Surgery, vol. 45, no. 4, 2019, pp. 404-413.
Liu L, Herrinton LJ, Alexeeff S, et al. Visual outcomes after cataract surgery in patients with type 2 diabetes. J Cataract Refract Surg. 2019;45(4):404-413.
Liu, L., Herrinton, L. J., Alexeeff, S., Karter, A. J., Amsden, L. B., Carolan, J., & Shorstein, N. H. (2019). Visual outcomes after cataract surgery in patients with type 2 diabetes. Journal of Cataract and Refractive Surgery, 45(4), 404-413. https://doi.org/10.1016/j.jcrs.2018.11.002
Liu L, et al. Visual Outcomes After Cataract Surgery in Patients With Type 2 Diabetes. J Cataract Refract Surg. 2019;45(4):404-413. PubMed PMID: 30638823.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Visual outcomes after cataract surgery in patients with type 2 diabetes. AU - Liu,Liyan, AU - Herrinton,Lisa J, AU - Alexeeff,Stacey, AU - Karter,Andrew J, AU - Amsden,Laura B, AU - Carolan,James, AU - Shorstein,Neal H, Y1 - 2019/01/09/ PY - 2018/07/19/received PY - 2018/10/23/revised PY - 2018/11/01/accepted PY - 2019/1/15/pubmed PY - 2020/5/20/medline PY - 2019/1/15/entrez SP - 404 EP - 413 JF - Journal of cataract and refractive surgery JO - J Cataract Refract Surg VL - 45 IS - 4 N2 - PURPOSE: To assess the relation between diabetic retinopathy (DR) severity, duration of diabetes, insulin dependence, and preoperative hemoglobin A1c (HbA1c) with visual outcome after phacoemulsification for cataract in patients with type 2 diabetes. SETTING: Kaiser Permanente Northern California, USA. DESIGN: Retrospective case series. METHODS: Information was obtained from the electronic medical record for patients, June 1, 2010, through May 31, 2015. Confounding factors and clustering of eyes within patients were controlled for using linear mixed-effects regression models for continuous outcomes and general estimating equations for dichotomous outcomes. RESULTS: The study included 65 370 patients; 28% had type 2 diabetes without DR, 5% nonproliferative DR, and 1.2% proliferative DR. Patients with diabetes and no DR were as likely as those without diabetes to achieve a corrected distance visual acuity (CDVA) of 20/20 (odds ratio, 1.01; 95% confidence interval, 0.94-1.10). The odds of a postoperative CDVA of 20/25 or worse increased with the severity of retinopathy duration of diabetes and insulin dependence, but not with the preoperative HbA1c. Although the odds of a postoperative CDVA of 20/20 was lower in patients with DR, every DR group averaged 4 lines of CDVA improvement, the same as patients without diabetes. A longer duration of diabetes, insulin dependence, and elevated HbA1c were not associated with worse postoperative outcomes. CONCLUSION: Patients with DR and cataracts were less likely to achieve a CDVA of 20/20 vision but gained as many lines of CDVA from phacoemulsification as patients without diabetes, showing no evidence that cataract surgery should be delayed in diabetic patients with elevated HbA1c. SN - 1873-4502 UR - https://www.unboundmedicine.com/medline/citation/30638823/Visual_outcomes_after_cataract_surgery_in_patients_with_type_2_diabetes_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0886-3350(18)30920-9 DB - PRIME DP - Unbound Medicine ER -