Citation
Vasanthapuram, Ravi, et al. "Dengue Virus Is an Under-recognised Causative Agent of Acute Encephalitis Syndrome (AES): Results From a Four Year AES Surveillance Study of Japanese Encephalitis in Selected States of India." International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases, vol. 84S, 2019, pp. S19-S24.
Vasanthapuram R, Shahul Hameed SK, Desai A, et al. Dengue virus is an under-recognised causative agent of acute encephalitis syndrome (AES): Results from a four year AES surveillance study of Japanese encephalitis in selected states of India. Int J Infect Dis. 2019;84S:S19-S24.
Vasanthapuram, R., Shahul Hameed, S. K., Desai, A., Mani, R. S., Reddy, V., Velayudhan, A., Yadav, R., Jain, A., Saikia, L., Borthakur, A. K., Mohan, D. G., Bandyopadhyay, B., Bhattacharya, N., Dhariwal, A. C., Sen, P. K., Venkatesh, S., Prasad, J., Laserson, K., & Srikantiah, P. (2019). Dengue virus is an under-recognised causative agent of acute encephalitis syndrome (AES): Results from a four year AES surveillance study of Japanese encephalitis in selected states of India. International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases, 84S, S19-S24. https://doi.org/10.1016/j.ijid.2019.01.008
Vasanthapuram R, et al. Dengue Virus Is an Under-recognised Causative Agent of Acute Encephalitis Syndrome (AES): Results From a Four Year AES Surveillance Study of Japanese Encephalitis in Selected States of India. Int J Infect Dis. 2019;84S:S19-S24. PubMed PMID: 30641206.
TY - JOUR
T1 - Dengue virus is an under-recognised causative agent of acute encephalitis syndrome (AES): Results from a four year AES surveillance study of Japanese encephalitis in selected states of India.
AU - Vasanthapuram,Ravi,
AU - Shahul Hameed,Shafeeq Keeran,
AU - Desai,Anita,
AU - Mani,Reeta Subramaniam,
AU - Reddy,Vijayalakshmi,
AU - Velayudhan,Anoop,
AU - Yadav,Ravi,
AU - Jain,Amita,
AU - Saikia,Lahari,
AU - Borthakur,A K,
AU - Mohan,Daiji Gogoi,
AU - Bandyopadhyay,Bhaswati,
AU - Bhattacharya,Nemai,
AU - Dhariwal,Akshay Chandra,
AU - Sen,Prabir Kumar,
AU - Venkatesh,Srinivas,
AU - Prasad,Jagdish,
AU - Laserson,Kayla,
AU - Srikantiah,Padmini,
Y1 - 2019/01/11/
PY - 2018/12/12/received
PY - 2019/01/02/revised
PY - 2019/01/04/accepted
PY - 2019/1/15/pubmed
PY - 2019/10/29/medline
PY - 2019/1/15/entrez
KW - Acute encephalitis syndrome
KW - Dengue
KW - Etiological agents
KW - India
SP - S19
EP - S24
JF - International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
JO - Int J Infect Dis
VL - 84S
N2 - BACKGROUND: Acute encephalitis syndrome (AES) surveillance in India has indicated that Japanese encephalitis virus (JEV) accounts for 5-35% of AES cases annually; the etiology remains unknown in the remaining cases. We implemented comprehensive AES surveillance to identify other etiological agents of AES, with emphasis on dengue virus. METHODS: Serum and cerebrospinal fluid (CSF) specimens were collected from patients enrolled prospectively in AES surveillance from 2014-2017 at selected sites of three high burden states of India. All samples were initially tested for JEV IgM. Specimens negative for JEV by serology were tested for IgM to scrub typhus, dengue virus (DEN), and West Nile virus; all JEV IgM-negative CSF samples were tested by PCR for S. pneumoniae, N. meningitidis, H. influenzae, herpes simplex virus type 1, enteroviruses and DEN. RESULTS: Of 10,107 AES patients, an etiology could be established in 49.2% of patients including JEV (16%), scrub typhus (16%) and DEN (5.2%) as the top three agents. Amongst the DEN positive cases (359/6892), seven (2%) were positive only for dengue virus RNA: one in serum and six in CSF. CONCLUSION: Amongst the pathogens identified, dengue accounted for 5% of all AES cases and was one of the three common etiological agents. These results underscore the importance of including dengue virus in routine testing of AES cases.
SN - 1878-3511
UR - https://www.unboundmedicine.com/medline/citation/30641206/Dengue_virus_is_an_under_recognised_causative_agent_of_acute_encephalitis_syndrome__AES_:_Results_from_a_four_year_AES_surveillance_study_of_Japanese_encephalitis_in_selected_states_of_India_
L2 - https://linkinghub.elsevier.com/retrieve/pii/S1201-9712(19)30019-0
DB - PRIME
DP - Unbound Medicine
ER -