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Treating alcohol-related liver disease from a public health perspective.
J Hepatol. 2019 02; 70(2):223-236.JH

Abstract

Herein, we describe the evolving landscape of alcohol-related liver disease (ALD) including the current global burden of disease and cost to working-aged people in terms of death and disability, in addition to the larger spectrum of alcohol-related heath complications and its wider impact on society. We further review the most effective and cost-effective public health policies at both a population and individual level. Currently, abstinence is the only effective treatment for ALD, and yet because the majority of ALD remains undetected in the community abstinence is initiated too late to prevent premature death in the majority of cases. We therefore hope that this review will help inform clinicians of the "public health treatment options" for ALD to encourage engagement with policy makers and promote community-based hepatology as a speciality, expanding our patient cohort to allow early detection, and thereby a reduction in the enormous morbidity and mortality associated with this disease.

Authors+Show Affiliations

Department of Gastroenterology and Hepatology, University Hospital Southampton NHS Foundation Trust, United Kingdom.National Drug Research Institute, Faculty of Health Sciences, Curtin University, Australia.Department of Gastroenterology and Hepatology, University Hospital Southampton NHS Foundation Trust, United Kingdom. Electronic address: nick.sheron@soton.ac.uk.University of Liverpool, Liverpool Science Park, United Kingdom.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

30658724

Citation

Hydes, Theresa, et al. "Treating Alcohol-related Liver Disease From a Public Health Perspective." Journal of Hepatology, vol. 70, no. 2, 2019, pp. 223-236.
Hydes T, Gilmore W, Sheron N, et al. Treating alcohol-related liver disease from a public health perspective. J Hepatol. 2019;70(2):223-236.
Hydes, T., Gilmore, W., Sheron, N., & Gilmore, I. (2019). Treating alcohol-related liver disease from a public health perspective. Journal of Hepatology, 70(2), 223-236. https://doi.org/10.1016/j.jhep.2018.10.036
Hydes T, et al. Treating Alcohol-related Liver Disease From a Public Health Perspective. J Hepatol. 2019;70(2):223-236. PubMed PMID: 30658724.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Treating alcohol-related liver disease from a public health perspective. AU - Hydes,Theresa, AU - Gilmore,William, AU - Sheron,Nick, AU - Gilmore,Ian, PY - 2018/09/13/received PY - 2018/10/31/revised PY - 2018/10/31/accepted PY - 2019/1/20/entrez PY - 2019/1/20/pubmed PY - 2020/6/20/medline KW - Alcohol KW - Policy KW - Public health SP - 223 EP - 236 JF - Journal of hepatology JO - J Hepatol VL - 70 IS - 2 N2 - Herein, we describe the evolving landscape of alcohol-related liver disease (ALD) including the current global burden of disease and cost to working-aged people in terms of death and disability, in addition to the larger spectrum of alcohol-related heath complications and its wider impact on society. We further review the most effective and cost-effective public health policies at both a population and individual level. Currently, abstinence is the only effective treatment for ALD, and yet because the majority of ALD remains undetected in the community abstinence is initiated too late to prevent premature death in the majority of cases. We therefore hope that this review will help inform clinicians of the "public health treatment options" for ALD to encourage engagement with policy makers and promote community-based hepatology as a speciality, expanding our patient cohort to allow early detection, and thereby a reduction in the enormous morbidity and mortality associated with this disease. SN - 1600-0641 UR - https://www.unboundmedicine.com/medline/citation/30658724/Treating_alcohol_related_liver_disease_from_a_public_health_perspective_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0168-8278(18)32520-0 DB - PRIME DP - Unbound Medicine ER -