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Anorexia Is Independently Associated with Decreased Muscle Mass and Strength in Community Dwelling Older Adults.
J Nutr Health Aging. 2019; 23(2):202-206.JN

Abstract

OBJECTIVES

We aimed to investigate the association between anorexia and sarcopenia in community dwelling older adults.

METHOD

Anorexia was assessed by Simplified Nutritional Appetite Questionnaire (SNAQ) and sarcopenia defined by EWSGOP criteria. Study participants consisted of 442 patients from Turkish validation study of the SNAQ. Study is designed as cross-sectional in community dwelling outpatients.

MEASUREMENTS

Muscle mass was determined by using bioimpedance analysis. Skeletal muscle mass index (SMMI) was calculated as SMM (kg)/height (m)2. Muscle strength was evaluated by hand grip strength (HGS) with Jamar hydraulic hand dynamometer. Gait speed (GS) was assessed by usual 4 meters speed. Depression and quality of life were assessed by using Geriatric Depression Scale (GDS) and Euro-Quality of Life-5D(EQ-5D). Univariate analysis and multivariate regression analysis were run to evaluate the association between poor appetite and components of sarcopenia.

RESULTS

Prevalences of low HGS, low gait speed and sarcopenia were higher in group with poor appetite (p=0.001, p<0.0001, p=0.036, respectively). Depression and constipation were more prevalent in participants with poor appetite (p<0.0001, p=0.033, respectively). SNAQ was correlated with SMMI and EQ-5D. Regression analysis showed that lower muscle mass, lower SMMI, and lower HGS were independently associated with poor appetite after adjustment for confounders. Neither gait speed nor diagnosis of sarcopenia was associated with poor appetite in regression analysis models.

CONCLUSION

We observed poor appetite has independent association with lower skeletal muscle mass and decreased muscle strength. Prospective studies are needed to evaluate exact relationship between poor appetite and sarcopenia.

Authors+Show Affiliations

Birkan İlhan, Dr. Ersin Arslan Training and Research Hospital, Department of Internal Medicine, Division of Geriatrics, 27010, Sahinbey, Gaziantep, Telephone: + 90 342 221 07 00 -3901 Fax: + 90 342 221 01 42, birkanilhan@hotmail.com.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30697631

Citation

İlhan, B, et al. "Anorexia Is Independently Associated With Decreased Muscle Mass and Strength in Community Dwelling Older Adults." The Journal of Nutrition, Health & Aging, vol. 23, no. 2, 2019, pp. 202-206.
İlhan B, Bahat G, Erdoğan T, et al. Anorexia Is Independently Associated with Decreased Muscle Mass and Strength in Community Dwelling Older Adults. J Nutr Health Aging. 2019;23(2):202-206.
İlhan, B., Bahat, G., Erdoğan, T., Kılıç, C., & Karan, M. A. (2019). Anorexia Is Independently Associated with Decreased Muscle Mass and Strength in Community Dwelling Older Adults. The Journal of Nutrition, Health & Aging, 23(2), 202-206. https://doi.org/10.1007/s12603-018-1119-0
İlhan B, et al. Anorexia Is Independently Associated With Decreased Muscle Mass and Strength in Community Dwelling Older Adults. J Nutr Health Aging. 2019;23(2):202-206. PubMed PMID: 30697631.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anorexia Is Independently Associated with Decreased Muscle Mass and Strength in Community Dwelling Older Adults. AU - İlhan,B, AU - Bahat,G, AU - Erdoğan,T, AU - Kılıç,C, AU - Karan,M A, PY - 2019/1/31/entrez PY - 2019/1/31/pubmed PY - 2019/1/31/medline KW - SNAQ KW - appetite KW - muscle mass KW - muscle strength KW - sarcopenia SP - 202 EP - 206 JF - The journal of nutrition, health & aging JO - J Nutr Health Aging VL - 23 IS - 2 N2 - OBJECTIVES: We aimed to investigate the association between anorexia and sarcopenia in community dwelling older adults. METHOD: Anorexia was assessed by Simplified Nutritional Appetite Questionnaire (SNAQ) and sarcopenia defined by EWSGOP criteria. Study participants consisted of 442 patients from Turkish validation study of the SNAQ. Study is designed as cross-sectional in community dwelling outpatients. MEASUREMENTS: Muscle mass was determined by using bioimpedance analysis. Skeletal muscle mass index (SMMI) was calculated as SMM (kg)/height (m)2. Muscle strength was evaluated by hand grip strength (HGS) with Jamar hydraulic hand dynamometer. Gait speed (GS) was assessed by usual 4 meters speed. Depression and quality of life were assessed by using Geriatric Depression Scale (GDS) and Euro-Quality of Life-5D(EQ-5D). Univariate analysis and multivariate regression analysis were run to evaluate the association between poor appetite and components of sarcopenia. RESULTS: Prevalences of low HGS, low gait speed and sarcopenia were higher in group with poor appetite (p=0.001, p<0.0001, p=0.036, respectively). Depression and constipation were more prevalent in participants with poor appetite (p<0.0001, p=0.033, respectively). SNAQ was correlated with SMMI and EQ-5D. Regression analysis showed that lower muscle mass, lower SMMI, and lower HGS were independently associated with poor appetite after adjustment for confounders. Neither gait speed nor diagnosis of sarcopenia was associated with poor appetite in regression analysis models. CONCLUSION: We observed poor appetite has independent association with lower skeletal muscle mass and decreased muscle strength. Prospective studies are needed to evaluate exact relationship between poor appetite and sarcopenia. SN - 1760-4788 UR - https://www.unboundmedicine.com/medline/citation/30697631/Anorexia_Is_Independently_Associated_with_Decreased_Muscle_Mass_and_Strength_in_Community_Dwelling_Older_Adults_ L2 - https://doi.org/10.1007/s12603-018-1119-0 DB - PRIME DP - Unbound Medicine ER -