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Parkinson's Disease.
Med Clin North Am. 2019 Mar; 103(2):337-350.MC

Abstract

The diagnosis of Parkinson disease (PD) is based on the presence of bradykinesia and either resting tremor or rigidity and there should be no features from the history or examination to suggest an alternative cause of parkinsonism. In addition to the motor manifestations of PD, there is a long list of nonmotor symptoms, several of which occur before motor signs and are considered "prodromal" PD. These are classified as neuropsychiatric, autonomic, sleep, and sensory. There are many medical options for the treatment of PD but levodopa remains the mainstay. Deep brain stimulation and other advanced therapies are also available.

Authors+Show Affiliations

Department of Neurology, University of Maryland School of Medicine, 110 South Paca Street, 3rd Floor, Baltimore, MD 21201, USA. Electronic address: sreich@som.umaryland.edu.Department of Neurology, University of Maryland School of Medicine, 110 South Paca Street, 3rd Floor, Baltimore, MD 21201, USA.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

30704685

Citation

Reich, Stephen G., and Joseph M. Savitt. "Parkinson's Disease." The Medical Clinics of North America, vol. 103, no. 2, 2019, pp. 337-350.
Reich SG, Savitt JM. Parkinson's Disease. Med Clin North Am. 2019;103(2):337-350.
Reich, S. G., & Savitt, J. M. (2019). Parkinson's Disease. The Medical Clinics of North America, 103(2), 337-350. https://doi.org/10.1016/j.mcna.2018.10.014
Reich SG, Savitt JM. Parkinson's Disease. Med Clin North Am. 2019;103(2):337-350. PubMed PMID: 30704685.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Parkinson's Disease. AU - Reich,Stephen G, AU - Savitt,Joseph M, Y1 - 2018/12/03/ PY - 2019/2/2/entrez PY - 2019/2/2/pubmed PY - 2019/2/12/medline KW - Dyskinesias KW - Levodopa KW - Parkinsonism KW - Parkinson’s disease KW - REM sleep behavioral disorder KW - Tremor SP - 337 EP - 350 JF - The Medical clinics of North America JO - Med Clin North Am VL - 103 IS - 2 N2 - The diagnosis of Parkinson disease (PD) is based on the presence of bradykinesia and either resting tremor or rigidity and there should be no features from the history or examination to suggest an alternative cause of parkinsonism. In addition to the motor manifestations of PD, there is a long list of nonmotor symptoms, several of which occur before motor signs and are considered "prodromal" PD. These are classified as neuropsychiatric, autonomic, sleep, and sensory. There are many medical options for the treatment of PD but levodopa remains the mainstay. Deep brain stimulation and other advanced therapies are also available. SN - 1557-9859 UR - https://www.unboundmedicine.com/medline/citation/30704685/Parkinson's_Disease_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0025-7125(18)30138-X DB - PRIME DP - Unbound Medicine ER -