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Relationship between sensory liking for fat, sweet or salt and cardiometabolic diseases: mediating effects of diet and weight status.
Eur J Nutr. 2020 Feb; 59(1):249-261.EJ

Abstract

PURPOSE

Previous works have been suggested that individual sensory liking is a predictor of dietary intake and weight status, and may consequently influence development of cardiometabolic diseases (CMDs). We investigated the association between sensory liking for fat-and-salt, fat-and-sweet, sweet or salt and the onset of hypertension, diabetes and cardiovascular diseases (CVDs) over 6 years in adults, and the mediating effects of dietary intake and body mass index (BMI).

METHODS

We examined the CMDs risk among 41,332 (for CVD and diabetes) and 37,936 (for hypertension) French adults (NutriNet-Santé cohort). Liking scores, individual characteristics, diet and anthropometry were assessed at baseline using questionnaires. Health events were collected during 6 years. Associations between sensory liking and CMDs risk, and the mediating effect of diet and BMI, were assessed using Cox proportional hazards models.

RESULTS

Sensory liking for fat-and-salt was associated with an increased risk of diabetes, hypertension and CVD [hazard ratios (HR) for 1-point increment of the sensory score: HR 1.30 (95% CI 1.18, 1.43), HR 1.08 (1.04, 1.13) and HR 1.10 (1.02, 1.19), respectively]. BMI and dietary intake both explained 93%, 98% and 70%, of the overall variation of liking for fat-and-salt liking in diabetes, hypertension and CVD, respectively. Liking for fat-and-sweet and liking for salt were also associated with an increased risk of diabetes [HR 1.09 (1.01, 1.17) and HR 1.09 (1.01, 1.18), respectively], whereas liking for sweet was associated with a decreased risk [HR 0.76 (0.69, 0.84)].

CONCLUSIONS

Higher liking for fat-and-salt is significantly associated with CMDs risk, largely explained by dietary intake and BMI. Our findings may help to guide effective targeted measures in prevention.

Authors+Show Affiliations

Université Paris 13, Equipe de Recherche en Epidémiologie Nutritionnelle, Centre de Recherche en Epidémiologie et Statistiques, Inserm (U1153), Inra (U1125), Cnam, COMUE Sorbonne Paris Cité, 93017, Bobigny, France. a.lampure@eren.smbh.univ-paris13.fr. EREN, SMBH Paris 13, 74 rue Marcel Cachin, 93017, Bobigny Cedex, France. a.lampure@eren.smbh.univ-paris13.fr.Université Paris 13, Equipe de Recherche en Epidémiologie Nutritionnelle, Centre de Recherche en Epidémiologie et Statistiques, Inserm (U1153), Inra (U1125), Cnam, COMUE Sorbonne Paris Cité, 93017, Bobigny, France.Université Libre de Bruxelles, Ecole de Santé Publique, Centre de Recherche en Epidémiologie, Biostatistiques et Recherche Clinique, 1070, Brussels, Belgium.Inra, UMR 1253, Science et Technologie du Lait et de l'Œuf, Rennes, France.Centre des Sciences du Go슩t et de l'Alimentation, UMR 6265 CNRS, UMR 1324 Inra, Dijon, France.Université Paris 13, Equipe de Recherche en Epidémiologie Nutritionnelle, Centre de Recherche en Epidémiologie et Statistiques, Inserm (U1153), Inra (U1125), Cnam, COMUE Sorbonne Paris Cité, 93017, Bobigny, France.Université Paris 13, Equipe de Recherche en Epidémiologie Nutritionnelle, Centre de Recherche en Epidémiologie et Statistiques, Inserm (U1153), Inra (U1125), Cnam, COMUE Sorbonne Paris Cité, 93017, Bobigny, France.Université Paris 13, Equipe de Recherche en Epidémiologie Nutritionnelle, Centre de Recherche en Epidémiologie et Statistiques, Inserm (U1153), Inra (U1125), Cnam, COMUE Sorbonne Paris Cité, 93017, Bobigny, France. Département de Santé Publique, Hôpital Avicenne (AP-HP), 93017, Bobigny, France.Université Paris 13, Equipe de Recherche en Epidémiologie Nutritionnelle, Centre de Recherche en Epidémiologie et Statistiques, Inserm (U1153), Inra (U1125), Cnam, COMUE Sorbonne Paris Cité, 93017, Bobigny, France. INRA, UMR 1110 MOISA, 34000, Montpellier, France.

Pub Type(s)

Journal Article
Observational Study

Language

eng

PubMed ID

30719567

Citation

Lampuré, Aurélie, et al. "Relationship Between Sensory Liking for Fat, Sweet or Salt and Cardiometabolic Diseases: Mediating Effects of Diet and Weight Status." European Journal of Nutrition, vol. 59, no. 1, 2020, pp. 249-261.
Lampuré A, Adriouch S, Castetbon K, et al. Relationship between sensory liking for fat, sweet or salt and cardiometabolic diseases: mediating effects of diet and weight status. Eur J Nutr. 2020;59(1):249-261.
Lampuré, A., Adriouch, S., Castetbon, K., Deglaire, A., Schlich, P., Péneau, S., Fezeu, L., Hercberg, S., & Méjean, C. (2020). Relationship between sensory liking for fat, sweet or salt and cardiometabolic diseases: mediating effects of diet and weight status. European Journal of Nutrition, 59(1), 249-261. https://doi.org/10.1007/s00394-019-01904-x
Lampuré A, et al. Relationship Between Sensory Liking for Fat, Sweet or Salt and Cardiometabolic Diseases: Mediating Effects of Diet and Weight Status. Eur J Nutr. 2020;59(1):249-261. PubMed PMID: 30719567.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Relationship between sensory liking for fat, sweet or salt and cardiometabolic diseases: mediating effects of diet and weight status. AU - Lampuré,Aurélie, AU - Adriouch,Solia, AU - Castetbon,Katia, AU - Deglaire,Amélie, AU - Schlich,Pascal, AU - Péneau,Sandrine, AU - Fezeu,Léopold, AU - Hercberg,Serge, AU - Méjean,Caroline, Y1 - 2019/02/05/ PY - 2018/07/23/received PY - 2019/01/17/accepted PY - 2019/2/6/pubmed PY - 2020/11/20/medline PY - 2019/2/6/entrez KW - Cardiovascular disease KW - Diabetes KW - Dietary intake KW - Hypertension KW - Mediating factor KW - Sensory liking SP - 249 EP - 261 JF - European journal of nutrition JO - Eur J Nutr VL - 59 IS - 1 N2 - PURPOSE: Previous works have been suggested that individual sensory liking is a predictor of dietary intake and weight status, and may consequently influence development of cardiometabolic diseases (CMDs). We investigated the association between sensory liking for fat-and-salt, fat-and-sweet, sweet or salt and the onset of hypertension, diabetes and cardiovascular diseases (CVDs) over 6 years in adults, and the mediating effects of dietary intake and body mass index (BMI). METHODS: We examined the CMDs risk among 41,332 (for CVD and diabetes) and 37,936 (for hypertension) French adults (NutriNet-Santé cohort). Liking scores, individual characteristics, diet and anthropometry were assessed at baseline using questionnaires. Health events were collected during 6 years. Associations between sensory liking and CMDs risk, and the mediating effect of diet and BMI, were assessed using Cox proportional hazards models. RESULTS: Sensory liking for fat-and-salt was associated with an increased risk of diabetes, hypertension and CVD [hazard ratios (HR) for 1-point increment of the sensory score: HR 1.30 (95% CI 1.18, 1.43), HR 1.08 (1.04, 1.13) and HR 1.10 (1.02, 1.19), respectively]. BMI and dietary intake both explained 93%, 98% and 70%, of the overall variation of liking for fat-and-salt liking in diabetes, hypertension and CVD, respectively. Liking for fat-and-sweet and liking for salt were also associated with an increased risk of diabetes [HR 1.09 (1.01, 1.17) and HR 1.09 (1.01, 1.18), respectively], whereas liking for sweet was associated with a decreased risk [HR 0.76 (0.69, 0.84)]. CONCLUSIONS: Higher liking for fat-and-salt is significantly associated with CMDs risk, largely explained by dietary intake and BMI. Our findings may help to guide effective targeted measures in prevention. SN - 1436-6215 UR - https://www.unboundmedicine.com/medline/citation/30719567/Relationship_between_sensory_liking_for_fat_sweet_or_salt_and_cardiometabolic_diseases:_mediating_effects_of_diet_and_weight_status_ L2 - https://dx.doi.org/10.1007/s00394-019-01904-x DB - PRIME DP - Unbound Medicine ER -