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[The course of color vision in early diabetic retinopathy treated with Ginkgo biloba extract. A preliminary double-blind versus placebo study].

Abstract

The therapeutic efficiency of the Ginkgo biloba extract was estimated in a double-blind trial, during a 6 months period, in 29 diabetic subjects with an early diabetic retinopathy evidenced by angiography, and associated with a blue-yellow dyschromatopsia. The functional criterion was the color vision evolution, studied by the Desaturated Panel D-15 and the 100-Hue Farnsworth test at the beginning of the trial and 6 months later. An improvement tendency was evidenced in subjects treated by Ginkgo biloba extract, and an aggravation in subjects with placebo, this improvement being statistically significative with the Desaturated Panel D-15 among subjects without retinal ischemia. These clinical results on visual function corroborate the pharmacological actions of Ginkgo biloba extract on diabetic retina.

Authors+Show Affiliations

,

Laboratoire de la Vision des Couleurs, Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, Paris.

Source

MeSH

Clinical Trials as Topic
Color Perception
Diabetic Retinopathy
Double-Blind Method
Humans
Middle Aged
Plant Extracts
Random Allocation
Time Factors

Pub Type(s)

Clinical Trial
English Abstract
Journal Article
Randomized Controlled Trial

Language

fre

PubMed ID

3072365

Citation

Lanthony, P, and J P. Cosson. "[The Course of Color Vision in Early Diabetic Retinopathy Treated With Ginkgo Biloba Extract. a Preliminary Double-blind Versus Placebo Study]." Journal Francais D'ophtalmologie, vol. 11, no. 10, 1988, pp. 671-4.
Lanthony P, Cosson JP. [The course of color vision in early diabetic retinopathy treated with Ginkgo biloba extract. A preliminary double-blind versus placebo study]. J Fr Ophtalmol. 1988;11(10):671-4.
Lanthony, P., & Cosson, J. P. (1988). [The course of color vision in early diabetic retinopathy treated with Ginkgo biloba extract. A preliminary double-blind versus placebo study]. Journal Francais D'ophtalmologie, 11(10), pp. 671-4.
Lanthony P, Cosson JP. [The Course of Color Vision in Early Diabetic Retinopathy Treated With Ginkgo Biloba Extract. a Preliminary Double-blind Versus Placebo Study]. J Fr Ophtalmol. 1988;11(10):671-4. PubMed PMID: 3072365.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The course of color vision in early diabetic retinopathy treated with Ginkgo biloba extract. A preliminary double-blind versus placebo study]. AU - Lanthony,P, AU - Cosson,J P, PY - 1988/1/1/pubmed PY - 1988/1/1/medline PY - 1988/1/1/entrez SP - 671 EP - 4 JF - Journal francais d'ophtalmologie JO - J Fr Ophtalmol VL - 11 IS - 10 N2 - The therapeutic efficiency of the Ginkgo biloba extract was estimated in a double-blind trial, during a 6 months period, in 29 diabetic subjects with an early diabetic retinopathy evidenced by angiography, and associated with a blue-yellow dyschromatopsia. The functional criterion was the color vision evolution, studied by the Desaturated Panel D-15 and the 100-Hue Farnsworth test at the beginning of the trial and 6 months later. An improvement tendency was evidenced in subjects treated by Ginkgo biloba extract, and an aggravation in subjects with placebo, this improvement being statistically significative with the Desaturated Panel D-15 among subjects without retinal ischemia. These clinical results on visual function corroborate the pharmacological actions of Ginkgo biloba extract on diabetic retina. SN - 0181-5512 UR - https://www.unboundmedicine.com/medline/citation/3072365/[The_course_of_color_vision_in_early_diabetic_retinopathy_treated_with_Ginkgo_biloba_extract__A_preliminary_double_blind_versus_placebo_study]_ L2 - https://medlineplus.gov/diabeticeyeproblems.html DB - PRIME DP - Unbound Medicine ER -