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Repellency Assessment of Nepeta cataria Essential Oils and Isolated Nepetalactones on Aedes aegypti.
Sci Rep. 2019 02 06; 9(1):1524.SR

Abstract

There is an increased need for improved and affordable insect repellents to reduce transmission of rapidly spreading diseases with high mortality rates. Natural products are often used when DEET cannot be afforded or accessed and when consumers choose not to use a synthetic repellent. The essential oils from two newly bred Nepeta cataria (catnip) plants representing two different chemotypes and their respective isolated nepetalactone isomers were evaluated as mosquito repellents against Aedes aegypti mosquitoes that transmit the Zika and Dengue virus in a one choice landing rate inhibition assay. A dose response curve was generated for each treatment and a time course analysis of repellency was performed over 24 hours with a N. cataria essential oil sample. The results indicate that all essential oil samples and their respective purified nepetalactone isomers were able to achieve greater than 95% repellency. Between two and four hours, the ability to repel more than 95% of the mosquitoes diminished. At the lowest concentrations tested, the nepetalactones and crude essential oil samples were more effective than DEET at reducing the number of mosquito landings.

Authors+Show Affiliations

New Use Agriculture and Natural Plant Products Program, Department of Plant Biology, Rutgers University, New Brunswick, New Jersey, USA.Department of Molecular, Cell and Systems Biology, University of California Riverside, Riverside, California, USA.Department of Molecular, Cell and Systems Biology, University of California Riverside, Riverside, California, USA.New Use Agriculture and Natural Plant Products Program, Department of Plant Biology, Rutgers University, New Brunswick, New Jersey, USA. College of Life Science, Shaanxi Normal University, Xi' an, Shaanxi, China.New Use Agriculture and Natural Plant Products Program, Department of Plant Biology, Rutgers University, New Brunswick, New Jersey, USA. Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey, USA.Department of Molecular, Cell and Systems Biology, University of California Riverside, Riverside, California, USA.New Use Agriculture and Natural Plant Products Program, Department of Plant Biology, Rutgers University, New Brunswick, New Jersey, USA. jimsimon@rutgers.edu. Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey, USA. jimsimon@rutgers.edu.

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

30728370

Citation

Reichert, William, et al. "Repellency Assessment of Nepeta Cataria Essential Oils and Isolated Nepetalactones On Aedes Aegypti." Scientific Reports, vol. 9, no. 1, 2019, p. 1524.
Reichert W, Ejercito J, Guda T, et al. Repellency Assessment of Nepeta cataria Essential Oils and Isolated Nepetalactones on Aedes aegypti. Sci Rep. 2019;9(1):1524.
Reichert, W., Ejercito, J., Guda, T., Dong, X., Wu, Q., Ray, A., & Simon, J. E. (2019). Repellency Assessment of Nepeta cataria Essential Oils and Isolated Nepetalactones on Aedes aegypti. Scientific Reports, 9(1), 1524. https://doi.org/10.1038/s41598-018-36814-1
Reichert W, et al. Repellency Assessment of Nepeta Cataria Essential Oils and Isolated Nepetalactones On Aedes Aegypti. Sci Rep. 2019 02 6;9(1):1524. PubMed PMID: 30728370.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Repellency Assessment of Nepeta cataria Essential Oils and Isolated Nepetalactones on Aedes aegypti. AU - Reichert,William, AU - Ejercito,Jadrian, AU - Guda,Tom, AU - Dong,Xujun, AU - Wu,Qingli, AU - Ray,Anandasankar, AU - Simon,James E, Y1 - 2019/02/06/ PY - 2018/02/15/received PY - 2018/11/20/accepted PY - 2019/2/8/entrez PY - 2019/2/8/pubmed PY - 2020/9/1/medline SP - 1524 EP - 1524 JF - Scientific reports JO - Sci Rep VL - 9 IS - 1 N2 - There is an increased need for improved and affordable insect repellents to reduce transmission of rapidly spreading diseases with high mortality rates. Natural products are often used when DEET cannot be afforded or accessed and when consumers choose not to use a synthetic repellent. The essential oils from two newly bred Nepeta cataria (catnip) plants representing two different chemotypes and their respective isolated nepetalactone isomers were evaluated as mosquito repellents against Aedes aegypti mosquitoes that transmit the Zika and Dengue virus in a one choice landing rate inhibition assay. A dose response curve was generated for each treatment and a time course analysis of repellency was performed over 24 hours with a N. cataria essential oil sample. The results indicate that all essential oil samples and their respective purified nepetalactone isomers were able to achieve greater than 95% repellency. Between two and four hours, the ability to repel more than 95% of the mosquitoes diminished. At the lowest concentrations tested, the nepetalactones and crude essential oil samples were more effective than DEET at reducing the number of mosquito landings. SN - 2045-2322 UR - https://www.unboundmedicine.com/medline/citation/30728370/Repellency_Assessment_of_Nepeta_cataria_Essential_Oils_and_Isolated_Nepetalactones_on_Aedes_aegypti_ DB - PRIME DP - Unbound Medicine ER -