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Recovery of Oligomeric Proanthocyanidins and Other Phenolic Compounds with Established Bioactivity from Grape Seed By-Products.
Molecules. 2019 Feb 14; 24(4)M

Abstract

Grape seeds are a copious part of the grape pomace produced by wine and juice industry and they represent an interesting source of phenolic compounds. Proanthocyanidins (PAs) are the main class of grape seed phenols and are important dietary supplements for their well-known beneficial properties. In this study enriched extracts obtained from Chardonnay and Pignoletto grape seeds were characterized for their proanthocyanidins and other minor phenolic compounds content and composition. Seed PAs were fractionated using Sephadex LH-20, using different ethanol aqueous solutions as mobile phase and analysed by normal phase HPLC-FLD-ESI-MS. Monomers, oligomers up to dodecamers and polymers were recorded in all samples. For both cultivars, the extracts showed a high content in PAs. The determination of other phenolic compounds was carried out using a HPLC-QqQ-ESI-MS and Chardonnay samples reported a greater content compared to Pignoletto samples. Contrary to PAs fraction, extracts obtained with ethanol/water 50/50 (v/v) presented a significant higher phenolic content than the others.

Authors+Show Affiliations

Interdepartmental Centre for Agri-Food Industrial Research, University of Bologna, via Quinto Bucci 336, 47521 Cesena (FC), Italy. federica.pasini5@unibo.it.Interdepartmental Centre for Agri-Food Industrial Research, University of Bologna, via Quinto Bucci 336, 47521 Cesena (FC), Italy. fabio.chinnici@unibo.it. Department of Agricultural and Food Sciences, University of Bologna, Piazza Goidanich 60, 47521 Cesena (FC), Italy. fabio.chinnici@unibo.it.Interdepartmental Centre for Agri-Food Industrial Research, University of Bologna, via Quinto Bucci 336, 47521 Cesena (FC), Italy. maria.caboni@unibo.it. Department of Agricultural and Food Sciences, University of Bologna, Piazza Goidanich 60, 47521 Cesena (FC), Italy. maria.caboni@unibo.it.Department of Nutrition and Food Science, University of Granada, Campus of Cartuja, 18071 Granada, Spain. vitoverardo@ugr.es. Institute of Nutrition and Food Technology (INYTA) 'José Mataix', Biomedical Research Centre, University of Granada, Avenida del Conocimiento s/n, E-18071 Granada, Spain. vitoverardo@ugr.es.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30769803

Citation

Pasini, Federica, et al. "Recovery of Oligomeric Proanthocyanidins and Other Phenolic Compounds With Established Bioactivity From Grape Seed By-Products." Molecules (Basel, Switzerland), vol. 24, no. 4, 2019.
Pasini F, Chinnici F, Caboni MF, et al. Recovery of Oligomeric Proanthocyanidins and Other Phenolic Compounds with Established Bioactivity from Grape Seed By-Products. Molecules. 2019;24(4).
Pasini, F., Chinnici, F., Caboni, M. F., & Verardo, V. (2019). Recovery of Oligomeric Proanthocyanidins and Other Phenolic Compounds with Established Bioactivity from Grape Seed By-Products. Molecules (Basel, Switzerland), 24(4). https://doi.org/10.3390/molecules24040677
Pasini F, et al. Recovery of Oligomeric Proanthocyanidins and Other Phenolic Compounds With Established Bioactivity From Grape Seed By-Products. Molecules. 2019 Feb 14;24(4) PubMed PMID: 30769803.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Recovery of Oligomeric Proanthocyanidins and Other Phenolic Compounds with Established Bioactivity from Grape Seed By-Products. AU - Pasini,Federica, AU - Chinnici,Fabio, AU - Caboni,Maria Fiorenza, AU - Verardo,Vito, Y1 - 2019/02/14/ PY - 2019/01/17/received PY - 2019/02/05/revised PY - 2019/02/11/accepted PY - 2019/2/17/entrez PY - 2019/2/17/pubmed PY - 2019/6/1/medline KW - LH-20 Sephadex KW - flavan-3-ols KW - grape seeds KW - oligomeric proanthocyanidins KW - phenolic compounds JF - Molecules (Basel, Switzerland) JO - Molecules VL - 24 IS - 4 N2 - Grape seeds are a copious part of the grape pomace produced by wine and juice industry and they represent an interesting source of phenolic compounds. Proanthocyanidins (PAs) are the main class of grape seed phenols and are important dietary supplements for their well-known beneficial properties. In this study enriched extracts obtained from Chardonnay and Pignoletto grape seeds were characterized for their proanthocyanidins and other minor phenolic compounds content and composition. Seed PAs were fractionated using Sephadex LH-20, using different ethanol aqueous solutions as mobile phase and analysed by normal phase HPLC-FLD-ESI-MS. Monomers, oligomers up to dodecamers and polymers were recorded in all samples. For both cultivars, the extracts showed a high content in PAs. The determination of other phenolic compounds was carried out using a HPLC-QqQ-ESI-MS and Chardonnay samples reported a greater content compared to Pignoletto samples. Contrary to PAs fraction, extracts obtained with ethanol/water 50/50 (v/v) presented a significant higher phenolic content than the others. SN - 1420-3049 UR - https://www.unboundmedicine.com/medline/citation/30769803/Recovery_of_Oligomeric_Proanthocyanidins_and_Other_Phenolic_Compounds_with_Established_Bioactivity_from_Grape_Seed_By_Products_ DB - PRIME DP - Unbound Medicine ER -