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Cognitive neuropsychiatric analysis of an additional large Capgras delusion case series.
Cogn Neuropsychiatry 2019; 24(2):123-134CN

Abstract

INTRODUCTION:

Although important to cognitive neuropsychiatry and theories of delusions, Capgras delusion has largely been reported in single case studies. Bell et al. [2017. Uncovering Capgras delusion using a large scale medical records database. British Journal of Psychiatry Open, 3(4), 179-185] previously deployed computational and clinical case identification on a large-scale medical records database to report a case series of 84 individuals with Capgras delusion. We replicated this approach on a new database from a different mental health service provider while additionally examining instances of violence, given previous claims that Capgras is a forensic risk.

METHODS:

We identified 34 additional cases of Capgras. Delusion phenomenology, clinical characteristics, and presence of lesions detected by neuroimaging were extracted.

RESULTS:

Although most cases involved misidentification of family members or partners, a notable minority (20.6%) included the misidentification of others. Capgras typically did not present as a monothematic delusion. Few cases had identifiable lesions with no evidence of right-hemisphere bias. There was no evidence of physical violence associated with Capgras.

CONCLUSIONS:

Findings closely replicate Bell et al. (2017). The majority of Capgras delusion phenomenology conforms to the "dual route" model although a significant minority of cases cannot be explained by this framework.

Authors+Show Affiliations

a Division of Psychiatry , University College London (UCL) , London , UK. b Institute of Psychiatry, Psychology and Neuroscience , King's College London , London , UK.a Division of Psychiatry , University College London (UCL) , London , UK. c Camden and Islington NHS Foundation Trust , London , UK.a Division of Psychiatry , University College London (UCL) , London , UK. c Camden and Islington NHS Foundation Trust , London , UK.a Division of Psychiatry , University College London (UCL) , London , UK. d South London and Maudsley NHS Foundation Trust , London , UK.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30794090

Citation

Currell, Emily A., et al. "Cognitive Neuropsychiatric Analysis of an Additional Large Capgras Delusion Case Series." Cognitive Neuropsychiatry, vol. 24, no. 2, 2019, pp. 123-134.
Currell EA, Werbeloff N, Hayes JF, et al. Cognitive neuropsychiatric analysis of an additional large Capgras delusion case series. Cogn Neuropsychiatry. 2019;24(2):123-134.
Currell, E. A., Werbeloff, N., Hayes, J. F., & Bell, V. (2019). Cognitive neuropsychiatric analysis of an additional large Capgras delusion case series. Cognitive Neuropsychiatry, 24(2), pp. 123-134. doi:10.1080/13546805.2019.1584098.
Currell EA, et al. Cognitive Neuropsychiatric Analysis of an Additional Large Capgras Delusion Case Series. Cogn Neuropsychiatry. 2019;24(2):123-134. PubMed PMID: 30794090.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cognitive neuropsychiatric analysis of an additional large Capgras delusion case series. AU - Currell,Emily A, AU - Werbeloff,Nomi, AU - Hayes,Joseph F, AU - Bell,Vaughan, Y1 - 2019/02/22/ PY - 2019/2/23/pubmed PY - 2019/2/23/medline PY - 2019/2/23/entrez KW - Delusional misidentification KW - forensic KW - neuropsychiatry KW - psychosis KW - schizophrenia SP - 123 EP - 134 JF - Cognitive neuropsychiatry JO - Cogn Neuropsychiatry VL - 24 IS - 2 N2 - INTRODUCTION:: Although important to cognitive neuropsychiatry and theories of delusions, Capgras delusion has largely been reported in single case studies. Bell et al. [2017. Uncovering Capgras delusion using a large scale medical records database. British Journal of Psychiatry Open, 3(4), 179-185] previously deployed computational and clinical case identification on a large-scale medical records database to report a case series of 84 individuals with Capgras delusion. We replicated this approach on a new database from a different mental health service provider while additionally examining instances of violence, given previous claims that Capgras is a forensic risk. METHODS:: We identified 34 additional cases of Capgras. Delusion phenomenology, clinical characteristics, and presence of lesions detected by neuroimaging were extracted. RESULTS:: Although most cases involved misidentification of family members or partners, a notable minority (20.6%) included the misidentification of others. Capgras typically did not present as a monothematic delusion. Few cases had identifiable lesions with no evidence of right-hemisphere bias. There was no evidence of physical violence associated with Capgras. CONCLUSIONS:: Findings closely replicate Bell et al. (2017). The majority of Capgras delusion phenomenology conforms to the "dual route" model although a significant minority of cases cannot be explained by this framework. SN - 1464-0619 UR - https://www.unboundmedicine.com/medline/citation/30794090/Cognitive_neuropsychiatric_analysis_of_an_additional_large_Capgras_delusion_case_series_ L2 - http://www.tandfonline.com/doi/full/10.1080/13546805.2019.1584098 DB - PRIME DP - Unbound Medicine ER -