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Jin's three-needle acupuncture technique for chronic fatigue syndrome: a study protocol for a multicentre, randomized, controlled trial.
Trials. 2019 Mar 04; 20(1):155.T

Abstract

BACKGROUND

With an unclear pathomechanism, no confirmed treatment regimen has been established for chronic fatigue syndrome (CFS). Acupuncture is applied as an alternative therapy for CFS. As a kind of acupuncture therapy, Jin's three-needle acupuncture (JTN) has been applied to treat CFS. However, few large-sample randomised controlled trials on JTN treatment for CFS have been reported. We designed this study to evaluate the efficacy and safety of JTN treatment for CFS.

METHOD/DESIGN

This study is a multicentre, single-blind, randomised controlled trial. Patients who meet the inclusion criteria will be recruited and randomly assigned to either the JTN treatment group or the basic acupuncture group. Both interventions will be conducted for five consecutive days per week and last for 2 weeks. The primary outcome is the effective rate based on the 14-item Fatigue Scale (FS-14) score. Other outcome measures include the Fatigue Assessment Scale (FAI), the Depression Status Inventory (DSI), and the Self-rating Anxiety Scale (SAS). Plasma adrenocorticotropic hormone (ACTH), plasma cortisol, and serum levels of IL-2 and IFN-γ will also be measured in this study. Adverse events will be observed and recorded for the safety evaluation.

DISCUSSION

This study may help to identify the efficacy and safety of JTN acupuncture treatment for CFS.

TRIAL REGISTRATION

Chinese Clinical Trial Registry, ID: ChiCTR-IOR-17011009 . Registered on 29 March 2017.

Authors+Show Affiliations

Guangzhou University of Traditional Chinese Medicine, Guangzhou, 510405, China.School of Basic Medical Science, Guangzhou University of Traditional Chinese Medicine, Guangzhou, 510006, China.Guangzhou University of Traditional Chinese Medicine, Guangzhou, 510405, China.Guangzhou University of Traditional Chinese Medicine, Guangzhou, 510405, China.The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine, Guangzhou, 510405, China. xinghuac@outlook.com.

Pub Type(s)

Clinical Trial Protocol
Journal Article

Language

eng

PubMed ID

30832713

Citation

Lin, Wenjia, et al. "Jin's Three-needle Acupuncture Technique for Chronic Fatigue Syndrome: a Study Protocol for a Multicentre, Randomized, Controlled Trial." Trials, vol. 20, no. 1, 2019, p. 155.
Lin W, Chen XL, Chen Q, et al. Jin's three-needle acupuncture technique for chronic fatigue syndrome: a study protocol for a multicentre, randomized, controlled trial. Trials. 2019;20(1):155.
Lin, W., Chen, X. L., Chen, Q., Wen, J., & Chen, X. (2019). Jin's three-needle acupuncture technique for chronic fatigue syndrome: a study protocol for a multicentre, randomized, controlled trial. Trials, 20(1), 155. https://doi.org/10.1186/s13063-019-3243-5
Lin W, et al. Jin's Three-needle Acupuncture Technique for Chronic Fatigue Syndrome: a Study Protocol for a Multicentre, Randomized, Controlled Trial. Trials. 2019 Mar 4;20(1):155. PubMed PMID: 30832713.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Jin's three-needle acupuncture technique for chronic fatigue syndrome: a study protocol for a multicentre, randomized, controlled trial. AU - Lin,Wenjia, AU - Chen,Xin-Lin, AU - Chen,Qi, AU - Wen,Junmao, AU - Chen,Xinghua, Y1 - 2019/03/04/ PY - 2018/08/24/received PY - 2019/02/08/accepted PY - 2019/3/6/entrez PY - 2019/3/6/pubmed PY - 2019/6/27/medline KW - Acupuncture KW - Chronic fatigue syndrome KW - Jin’s three-needle technique KW - Randomised controlled trial SP - 155 EP - 155 JF - Trials JO - Trials VL - 20 IS - 1 N2 - BACKGROUND: With an unclear pathomechanism, no confirmed treatment regimen has been established for chronic fatigue syndrome (CFS). Acupuncture is applied as an alternative therapy for CFS. As a kind of acupuncture therapy, Jin's three-needle acupuncture (JTN) has been applied to treat CFS. However, few large-sample randomised controlled trials on JTN treatment for CFS have been reported. We designed this study to evaluate the efficacy and safety of JTN treatment for CFS. METHOD/DESIGN: This study is a multicentre, single-blind, randomised controlled trial. Patients who meet the inclusion criteria will be recruited and randomly assigned to either the JTN treatment group or the basic acupuncture group. Both interventions will be conducted for five consecutive days per week and last for 2 weeks. The primary outcome is the effective rate based on the 14-item Fatigue Scale (FS-14) score. Other outcome measures include the Fatigue Assessment Scale (FAI), the Depression Status Inventory (DSI), and the Self-rating Anxiety Scale (SAS). Plasma adrenocorticotropic hormone (ACTH), plasma cortisol, and serum levels of IL-2 and IFN-γ will also be measured in this study. Adverse events will be observed and recorded for the safety evaluation. DISCUSSION: This study may help to identify the efficacy and safety of JTN acupuncture treatment for CFS. TRIAL REGISTRATION: Chinese Clinical Trial Registry, ID: ChiCTR-IOR-17011009 . Registered on 29 March 2017. SN - 1745-6215 UR - https://www.unboundmedicine.com/medline/citation/30832713/Jin's_three_needle_acupuncture_technique_for_chronic_fatigue_syndrome:_a_study_protocol_for_a_multicentre_randomized_controlled_trial_ L2 - https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-019-3243-5 DB - PRIME DP - Unbound Medicine ER -