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[Chemotherapy trial in the battle against Schistosoma haematobium in an irrigated sahelian zone in Niger].
Med Trop (Mars). 1986 Jan-Mar; 46(1):21-30.MT

Abstract

This study of S. haematobium infection in communities associated with irrigated schemes shows that prevalence rates are unusually high in adults, especially in men; and distribution disease is probably associated with at least the following three factors: (i) distance of the place of residence from the main transmission sites (ii) the dynamics of transmission in the waterbody and (iii) the human/water contact and contamination patterns. During this chemotherapy trial, at the first survey, only a little more than half (57.47%) of the people recorded in the census was present. Five visits of the survey team were necessary to obtain a compliance rate of 80.51% of the entire population. The indifference of the local people to seek diagnosis and treatment increased with succeeding surveys. It is only, during a subsequent treatment survey, carried out during the season of low agricultural activity and following an official written convocation, that a compliance rate similar to that of the first survey was recorded. If treatment is not given immediately after diagnosis as many as a fifth of positive cases do not appear for treatment. Oltipraz and praziquantel were administered. Their effectiveness could not be truly compared as there was a time lag of six months separating the administration of the treatments. However, based on the results of this trial both drugs gave good results especially in egg output intensity. But, a decrease of this parameter was also observed in non treated people. Seasonal variations of egg output or decrease of transmission could be involved.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

fre

PubMed ID

3084903

Citation

Sellin, B, et al. "[Chemotherapy Trial in the Battle Against Schistosoma Haematobium in an Irrigated Sahelian Zone in Niger]." Medecine Tropicale : Revue Du Corps De Sante Colonial, vol. 46, no. 1, 1986, pp. 21-30.
Sellin B, Rey JL, Simonkovich E, et al. [Chemotherapy trial in the battle against Schistosoma haematobium in an irrigated sahelian zone in Niger]. Med Trop (Mars). 1986;46(1):21-30.
Sellin, B., Rey, J. L., Simonkovich, E., Sellin, E., & Mouchet, F. (1986). [Chemotherapy trial in the battle against Schistosoma haematobium in an irrigated sahelian zone in Niger]. Medecine Tropicale : Revue Du Corps De Sante Colonial, 46(1), 21-30.
Sellin B, et al. [Chemotherapy Trial in the Battle Against Schistosoma Haematobium in an Irrigated Sahelian Zone in Niger]. Med Trop (Mars). 1986 Jan-Mar;46(1):21-30. PubMed PMID: 3084903.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Chemotherapy trial in the battle against Schistosoma haematobium in an irrigated sahelian zone in Niger]. AU - Sellin,B, AU - Rey,J L, AU - Simonkovich,E, AU - Sellin,E, AU - Mouchet,F, PY - 1986/1/1/pubmed PY - 1986/1/1/medline PY - 1986/1/1/entrez SP - 21 EP - 30 JF - Medecine tropicale : revue du Corps de sante colonial JO - Med Trop (Mars) VL - 46 IS - 1 N2 - This study of S. haematobium infection in communities associated with irrigated schemes shows that prevalence rates are unusually high in adults, especially in men; and distribution disease is probably associated with at least the following three factors: (i) distance of the place of residence from the main transmission sites (ii) the dynamics of transmission in the waterbody and (iii) the human/water contact and contamination patterns. During this chemotherapy trial, at the first survey, only a little more than half (57.47%) of the people recorded in the census was present. Five visits of the survey team were necessary to obtain a compliance rate of 80.51% of the entire population. The indifference of the local people to seek diagnosis and treatment increased with succeeding surveys. It is only, during a subsequent treatment survey, carried out during the season of low agricultural activity and following an official written convocation, that a compliance rate similar to that of the first survey was recorded. If treatment is not given immediately after diagnosis as many as a fifth of positive cases do not appear for treatment. Oltipraz and praziquantel were administered. Their effectiveness could not be truly compared as there was a time lag of six months separating the administration of the treatments. However, based on the results of this trial both drugs gave good results especially in egg output intensity. But, a decrease of this parameter was also observed in non treated people. Seasonal variations of egg output or decrease of transmission could be involved. SN - 0025-682X UR - https://www.unboundmedicine.com/medline/citation/3084903/[Chemotherapy_trial_in_the_battle_against_Schistosoma_haematobium_in_an_irrigated_sahelian_zone_in_Niger]_ DB - PRIME DP - Unbound Medicine ER -