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Lichen Sclerosus

Abstract
Lichen sclerosus (LS) is a chronic inflammatory disease. It was first described by Hallopeau in 1881. Since then, multiple names have been used to describe this condition such as leukoplakia, kraurosis vulvae, balanitis xerotica obliterans, and lichen sclerosis et atrophicus. In 1976, the International Society for the Study of Vulvovaginal Disease adopted the term of lichen sclerosus. LS is a mucocutaneous autoimmune disorder characterized by hypopigmentation and skin atrophy. It involves most commonly the genital skin, less often the extragenital sites. LS is more common in women than in men. It may cause phimosis or scarring of the vaginal introitus. The diagnosis is based on the clinical features, but it is often confirmed by biopsy. The lesions can evolve towards the destruction of anatomic structures, functional impairment and a potential risk for malignant evolution. Thus, treatment and long term follow-up are mandatory.

Publisher

StatPearls Publishing
Treasure Island (FL)

Language

eng

PubMed ID

30855834

Citation

Chamli A, Souissi A: Lichen Sclerosus.StatPearls. StatPearls Publishing, 2019, Treasure Island (FL).
Chamli A, Souissi A. Lichen Sclerosus. StatPearls. Treasure Island (FL): StatPearls Publishing; 2019.
Chamli A & Souissi A. (2019). Lichen Sclerosus. In StatPearls. Treasure Island (FL): StatPearls Publishing;
Chamli A, Souissi A. StatPearls. Treasure Island (FL): StatPearls Publishing; 2019.
* Article titles in AMA citation format should be in sentence-case
TY - CHAP T1 - Lichen Sclerosus BT - StatPearls A1 - Chamli,Amal, AU - Souissi,Asmahane, Y1 - 2019/01// PY - 2019/3/12/pubmed PY - 2019/3/12/medline PY - 2019/3/12/entrez N2 - Lichen sclerosus (LS) is a chronic inflammatory disease. It was first described by Hallopeau in 1881. Since then, multiple names have been used to describe this condition such as leukoplakia, kraurosis vulvae, balanitis xerotica obliterans, and lichen sclerosis et atrophicus. In 1976, the International Society for the Study of Vulvovaginal Disease adopted the term of lichen sclerosus. LS is a mucocutaneous autoimmune disorder characterized by hypopigmentation and skin atrophy. It involves most commonly the genital skin, less often the extragenital sites. LS is more common in women than in men. It may cause phimosis or scarring of the vaginal introitus. The diagnosis is based on the clinical features, but it is often confirmed by biopsy. The lesions can evolve towards the destruction of anatomic structures, functional impairment and a potential risk for malignant evolution. Thus, treatment and long term follow-up are mandatory. PB - StatPearls Publishing CY - Treasure Island (FL) UR - https://www.unboundmedicine.com/medline/citation/30855834/StatPearls:_Lichen_Sclerosus L2 - https://www.ncbi.nlm.nih.gov/books/NBK538246 DB - PRIME DP - Unbound Medicine ER -
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